The Meakins-Christie Laboratories is one of the premiere centres for pulmonary research in the world. It comprises the largest group of investigators within the Translational Research in Respiratory Diseases Program at the Research Institute of the McGill University Health Centre. Our overall mission is to better understand the pathobiology of respiratory disorders in order to drive innovations in respiratory disease prevention, diagnosis, and therapy.
According to the World Health Organization, respiratory disorders such as obstructive lung diseases and pulmonary infections are leading causes of death world-wide (second only to heart attack & stroke). Research is focused around four main themes: chronic airways disease, lung injury and infection, neuromuscular dysfunction in respiratory diseases, and sleep-disordered breathing. Within the above themes, a multidisciplinary approach is used to study the basic mechanisms of asthma, chronic obstructive pulmonary disease, pulmonary infections, cystic fibrosis, sleep apnea, respiratory muscle disorders, pulmonary fibrosis, lung injury, and rare respiratory diseases. The research involves the study of human physiology & tissues in parallel with relevant animal & cell culture models. Research is facilitated by the availability of a variety of core facilities for both clinical and fundamental studies.
Our Faculty Members are an equal mix of PhD and MD scientists, thus ensuring that basic science and patient-oriented research questions and techniques are brought together to help drive translational pulmonary research toward successful clinical applications. Longstanding strong collaborations with the Respiratory Epidemiology and Clinical Research Unit (RECRU), MUHC, Montreal Children’s Hospital, and Montreal Chest Institute further support fundamental, clinical, and translational research projects. Finally, one of the most important missions of the Meakins-Christie Laboratories is the training of graduate students and postdoctoral fellows from around the world. To this achieve this goal, there are weekly seminars, work-in-progress sessions, and a variety of mentoring activities as well as social functions organized by our students & fellows association (SPiRE). Numerous McGill courses and workshops are also given at the Meakins-Christie Laboratories.