Category Archives: Carolyn Baglole

View her faculty profile here: Carolyn Baglole, PhD
Associate Professor, Department of Medicine, McGill Universiy
Research Theme: Cellular and molecular signalling pathways which regulate chronic lung disease caused by cigarette smoke
Keywords: chronic obstructive pulmonary disease • toxicology • cigarette smoke • inflammation • lungs • cannabis
View Carolyn Baglole’s recent posts and news below.

Dr. Carolyn Baglole ensures that cannabis-related research continues during the pandemic

Cannabis-related research continues

Since the start of the pandemic, Dr. Carolyn Baglole, member of the Meakins-Christie Laboratories and Director of the McGill Research Centre for Cannabis, has ensured that cannabis-related research continues. Although research has been considerably ramped down, Dr. Baglole asserts:

“We still have so much to learn about cannabis,” “We need to keep this research on track so we can further the science and better inform policymakers and the public.”

Dr. Carolyn Baglole

Although Dr. Baglole did not begin her scientific career with cannabis-related research in mind, the legalization of cannabis in Canada and other countries around the world has led to a growing interest in and use of the product for medical purposes. Recognizing the need for more information, researchers like Dr. Baglole are focusing on the potentially positive effects of cannabidiol (CBD) on the human body. CBD is the compound found in cannabis that has medicinal uses as it does not have psychotropic side effects. Early research suggests it may have an effect on the immune system and anti-inflammatory properties.

The Association québécoise de l’industrie du cannabis (AQIC) has launched the CBD Research Partnership Fund, which Dr. Baglole hopes will help to increase interest and support for this field of research into CBD and its yet-to-be discovered medicinal benefits. Partnerships such as this one will ensure that cannabis-related research continues far into the future.

“I hope that the CBD Research Partnership Fund has a feed-forward effect for CBD research at McGill,” Baglole says. “I hope it shows the high-quality work that can come out of this kind of research partnership and attracts additional funding so that we’re able to support more cutting-edge research projects.”

Read the interview with Dr. Carolyn Baglole here:

McGill Research Centre for Cannabis, led by Dr. Carolyn Baglole, establishes a CBD Research Partnership Fund to mark the second anniversary of cannabis legalization in Canada

CBD Research Partnership Fund

A CBD Research Partnership Fund has been launched by the Association québécoise de l’industrie du cannabis (AQIC) and the McGill Research Centre for Cannabis. Dr. Carolyn Baglole, Director of the McGill Research Centre for Cannabis, believes this increased research funding will result in increased safety and effectiveness of medical CBD.

“We are pleased to partner with the AQIC in a project that provides much-needed financial support for CBD research, the results of which ultimately will give a better understanding of the safety and efficacy of CBD. A partnership between McGill and the private sector will allow us to combine resources, thereby raising the bar of scientific discovery, and the promise that medical cannabis holds.”

Dr. Carolyn Baglole

The launch of this CBD Research Partnership Fund marks the second anniversary of the legalization of the use of cannabis in Canada.

Read the full article:

Advancing the Safety and Efficacy of Cannabidiol (CBD) for Medical Use AQIC and the McGill Research Centre for Cannabis Establish a CBD Research Partnership Fund. McGill’s Health e-News. Oct 19, 2020. Photo credit: Association québécoise de l’industrie du cannabis (AQIC)

Dr. Carolyn Baglole on the impact of legalization on cannabis research in Canada

The Future of Cannabis Research

Dr. Carolyn Baglole of the Meakins-Christie Laboratories talks about the future of cannabis research in Canada, and how legalization has had a positive impact in this field. Funding opportunities have increased considerably and barriers to research, such as access to different cannabis products, have diminished. Stigmas surrounding medical cannabis continue to exist, but the future of cannabis research in Canada is evident.

Julie Quenneville, President of the McGill University Health Centre Foundation, recently spoke to Dr. Baglole on CJAD as part of the Health Matters series.

Where to listen:

Dr. Carolyn Baglole received a CIHR catalyst grant: Health Effects of Vaping for her grant entitled: Utility of a Preclinical Model to Study the Impact of Vaping Products on Cardiopulmonary Outcomes.

Impact of Vaping on Cardiopulmonary Outcomes

Dr. Carolyn Baglole, with Dr. Koren Kathleen Mann, received a CIHR Catalyst Grant: Health Effects of Vaping. The title of the grant is: “Utility of a Preclinical Model to Study the Impact of Vaping Products on Cardiopulmonary Outcomes.”.

The objective of the grant is to investigate the effects of vaping products on cardiopulmonary outcomes, alone and in conjunction with SARS-CoV-2 infection. They propose to develop a mouse model of vaping to understand the effects on the lung, as well as the heart, vessels, and immune system. They will further use a mouse model to test whether vaping can alter that infection of SARS-CoV-2, the virus responsible for COVID-19. This model could then be used to test new vaping products as they enter the market for toxicity and/or to test therapies to counter act the severe toxicities of vaping.

Congrats Carolyn and the rest of the team!

Read more:

2020-2021 Quebec respiratory health network results for Student supplementary grant program - Meakins-Christie recipients

Meakins and RESP trainees receive QRHN funding

Congratulations to the following students and fellows for receiving the 2020-2021 Supplementary grant program from the Quebec Respiratory Health Research Network.

  • Dr. Inès levade. PDF with Dr. Dao Nguyen. Title: Identification of genetic variants of Pseudomonas aeruginosa involved in the progression of lung disease in patients with cystic fibrosis
  • Dr. Daniella Massierer. PDF with Dr. Tania Janaudis-Ferreira. Title: Predictive validity of the handgrip strength and 1-minute sit to-stand tests for 30-day readmissions after acute exacerbation of COPD: a feasibility study.
  • Dr. Hussein Traboulsi. PDF with Dr. Carolyn Baglole. Title: Establishing the role of the aryl hydrocarbon receptor (AhR) in pulmonary fibrosis
  • Wided Akik. PhD student with Dr. Larry Lands. Title: Mechanisms Underlying Corticosteroid Insensitivity Induction by Interleukin-17A in Bronchial Epithelial Cells.
  • Saad Razzaq. MSc student with Dr. Dennis Jensen. Title: Components of the COPD Assessment Test associated with cardiopulmonary exercise test outcomes in the Canadian Cohort Obstructive Lung Disease (CanCOLD) study.
  • Emily Wilson. MSc student with Dr. Carolyn Baglole. Title: AhR Activation by Cannabinoids Protects Against Lung Inflammation

More about the Quebec Respiratory Health Research Network (QRHN).

FRQS Salary awards to meakins-christie, RECRU, and respiratory research members for 2020

2020-2021 FRQS Salary Awards

Congratulations to the following Meakins-Christie faculty, RECRU faculty, and RESP program members who received funding from the 2020-2021 FRQS Research Scholars and Clinical Research Scholars Salary Award Competition!

  • Carolyn Baglole – Programme de bourses de chercheur-boursier Senior – for her project entitled: Pathogenèse des maladies pulmonires environnementales : de mechanisms aux traitements. (4 year funding)
  • Sushmita Pamidi – Programme de bourses de chercheur-boursier Clinicien – Junior 2

funding news for the Meakins-Christie Laboratories

Five CIHR Project Grants awarded!

Five CIHR Project grants were awarded to Meakins and RECRU members in the Fall 2019 competition. Congratulations to ALL!

Basil Petrof. Co-Applicant: Sabah Hussain. Title: Understanding the basis of diaphragmatic weakness in critical illness. Ranked 1st in the Respiratory System Peer Review Committee!

Maziar Divangahi. Title: Reprogramming HSCs to generate protective trained immunity against TB. Ranked 2nd in the Immunology & Transplantation Peer Review Committee!

Maziar Divangahi. Title: Targeting the eicosanoid/macrophage axis to enhance host defense against influenza virus infection.

Carolyn Baglole. Co-Principal Investigator: Ilan Azuelos. Co-Applicants: Andrea Benedetti, Imed Gallouzi. Title: Prognostic and Therapeutic Utility of Human Antigen R (HuR) in Fibrosis.

Faiz Ahmad Khan. Co-Principal Investigators: Glenda Sandy, Christopher Fletcher, Neil Andersson. Co-Applicants: Marie Rochette, Carmen Sicilia, Dick Menzies, Stephanie Law, Richard Long, Alison Doucet. Title: Community Health Workers in Tuberculosis Prevention & Care Services in Nunavik.

Quebec Respiratory health network logo

Epigenetics of vaping project funded by QRHN

Congratulations Carolyn Baglole! The Quebec Respiratory Health Network (QRHN) awarded one (1) year funding for her collaborative project entitled “Evaluate the Epigenetic Lung Effects of Vaping“. The project was funded through the Priority Projects Grants Program (2019-2020).

The Mentorship program of the QRHN also funded Tania Janaudis-Ferreira. Title: Improving ACCEPTance and uptake of Pulmonary Rehabilitation after acute exacerbation of chronic obstructive pulmonary disease – The ACCEPT PR STUDY. Dr. Janaudis-Ferreira is an Associate Member of the Meakins-Christie Laboratories and an investigator at the RI-MUHC Respiratory Program.

The Quebec Respiratory Health research Network (QRHN) is one of 20 thematic networks funded by the Fonds de recherche du Québec – Santé. It brings together more than 490 researchers, pulmologists, health professionals and students. The goal of the Network is to provide a provincial structure in respiratory health based on the participation of researchers in this field, to promote the integration of the different research components, namely clinical, evaluative, epidemiological and fundamental research.

Cannabis-Centre-Launch-Dean-Eidelman-Baglole-Quenneville-Thompson

McGill Research Centre for Cannabis

The new McGill Research Centre for Cannabis held its inaugural Science and Research Day on Thursday, October 17, 2019, at the RI-MUHC. The event took place one year following the federal government’s 2018 legalization of cannabis for medicinal and recreational use.

During the event, opening remarks were provided by Dr. Baglole, Dr. David Eidelman (Vice-Principal (Health Affairs) and Dean of Medicine) and Julie Quenneville (MUHC Foundation President).

Canada is uniquely positioned to establish international precedents to inform on cannabis use and policy for countries around the world. The mission of the McGill Research Centre for Cannabis is to offer a hub for integrated cannabis-related research activities. These activities span agriculture/plant sciences, chemistry, biomedical and socioeconomics. The outcomes of this research will provide evidence based knowledge and greatly impact cannabis-related decisions/policies surrounding health, society and law.

Dr. Carolyn Baglole is the Centre’s Director. Read more about how the centre will focus its research efforts on increasing our evidence-based knowledge about the biomedical, horticultural and legal aspects of cannabis use. Specifically, the RI-MUHC and Faculty of Medicine team will look at the biomedical potential of cannabis, including cannabis-based immune therapy; product safety; customized delivery methods; and precision medicine. 

Read the complete article here:

The McGill Research Centre for Cannabis holds inaugural Science and Research Day. McGill Health e-News. Oct 24, 2019.

About the McGill Research Centre for Cannabis: https://www.mcgill.ca/cannabis/