Category Archives: News

Respiratory Research News from the Meakins-Christie Laboratories and the RESP program of the RI-MUHC. View our latest funding results, faculty and trainee awards, and our research featured in the media.

Human Airway Branch Variation and Chronic Obstructive Pulmonary Disease

Airway Branching Associated with COPD Risk

Dr. Benjamin Smith, in collaboration with Dr. Carolyn Baglole and Columbia University Irving Medical Center, published “Human Airway Branch Variation and Chronic Obstructive Pulmonary Disease” in the Proceedings of the National Academy of Sciences. Together, their study shows that the internal anatomy of our lungs is surprisingly variable. Furthermore, some of those variations are associated with a greater risk of chronic obstructive pulmonary disease (COPD). (January 2018)

View full publication: Human airway branch variation and chronic obstructive pulmonary disease. Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR Jr, Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG; MESA Lung and SPIROMICS investigators. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E974-E981. doi: 10.1073/pnas.1715564115. Epub 2018 Jan 16. PMID: 29339516

View articles and interviews about this research:

Cell 2018: BCG Educates hematopoietic stem cells to generate protective innate immunity against TB. M Divangahi

BCG-iv Induces Innate Immune Protection Against M. tuberculosis

Dr. Maziar Divangahi, his lab, and collaborators at McGill University and University of Montreal published a paper in Cell. Their work shows BCG-iv induces trained immunity through education of hematopoietic stem cells and offers long-term innate immune protection against M. tuberculosis infection. 

Up until now, efforts in generating a vaccine against TB have been mainly focused on T cells, with very disappointing outcomes in both pre-clinical as well as clinical trials. Now, Dr. Divangahi’s and Barreiro’s teams have shown for the first time that when BCG is administered to mice in a way that enables access to the bone marrow, it can reprogram stem cells. Dr. Eva Kaufmann, a postdoctoral fellow working on the project, was also interviewed by Radio-Canada. (January 2018) 

About the study

BCG educates hematopoietic stem cells to generate protective innate immunity against tuberculosis by Eva Kaufmann, Joaquin Sanz, Jonathan L. Dunn, Nargis Khan, Laura E. Mendonça, Alain Pacis, Fanny Tzelepis, Erwan Pernet, Anne Dumaine, Jean-Christophe Grenier, Florence Mailhot-Léonard, Eisha Ahmed, Jad Belle, Rickvinder Besla, Bruce Mazer, Irah L. King, Anastasia Nijnik, Clinton S. Robbins, Luis B. Barreiro, and Maziar Divangahi, was published Jan. 11, 2018, in Cell. DOI: 10.1016/j.cell.2017.12.031

This study was funded by the Canadian Institutes of Health Research.

View articles and interviews about this research:

Respiratory Research Canada: Meakins-Christie Laboratories of the RI-MUHC

2017 Respiratory Research News Meakins-Christie Labs

  • Dr. Elizabeth Fixman‘s research with Dr. Brian Ward (IDIGH program) was featured in the 2017 CDMRP Annual Report for her DoD funded research on “STAT6-Dependent Bridging of Innate and Th2 Adaptive Immunity in the Lung”. (December 2017)
  • Dr. Ilan Azuelos was awarded 1 year funding from the  Réseau en santé respiratoire du FRQS Programme de développement de jeunes chercheurs en mentorat for his grant entitled “The role of mTOR on mitochondrial function, structure and dynamics during TGFß-induced fibroblast differentiation”. (November 2017)
  • Dr. Jean Bourbeau was awarded funding from the Réseau en santé respiratoire du FRQS Concours projets équipes for his project entitled: De la clinique au laboratoire : mécanisme d’action de l’azithromycine pour la prévention des exacerbations pulmonaires MPOC. (November 2017)
  • Congratulations to Lisa Hennemann (MSc student with Dr. Dao Nguyen) for receiving the “Concours compléments de bourse” from the Réseau en santé respiratoire du FRQS. Her project title is: The role of intracellular Pseudomonas aeruginosa in the development of persistent infections. (November 2017)
  • The Réseau en santé respiratoire du FRQS awarded the renewal of a team grant entitled “Importance et prévention de la dysfonction diaphragmatique associée à la ventilation chez le nourrisson”. Team members include: Dr. Basil Petrof (Meakins and RESP Program), Dr. Guilherme Sant’Anna (RESP Program), Dr. Guillaume Emeriaud (St. Justine), Dr. Jean-Paul Praud (U Sherbrooke), Dr. Hugo Théôret (St. Justine), and Sylvain Morneau (St. Justine).  (November 2017)
  • A publication by Dr. Russell Hepple and Dr. Tanja Taivassalo was featured during the ATS Assembly of Pulmonary Rehabilitation Journal Club on November 29, 2017. To view the publication: ‘Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease’. To register for the webinar, click here. (November 2017)
  • Congratulations to Dr. Jean Bourbeau on receiving the 2017 Distinguished CHEST Educator Award. This distinction places the designees within the top 5% of CHEST’s international faculty and recognizes the achievements of members who have made significant and longterm contributions to CHEST education by serving as CHEST committee chairs, vice-chairs, faculty, members, for programs and activities at CHEST. (October 2017)
  • Ellen Zhou, a former trainee under the supervision of Dr. Simon Rousseau, and now a MD-PhD student at McGill, received the 2017 Canadian Medical Hall of Fame Award. (September 2017) 
  • The 2017 Joint Summer Student Research Day was held August 10, 2017. The participating RI-MUHC programs were: RESP, CHHD, CRP, MeDIC, and CHAL. There were 53 oral and poster presentations, 13 of which came from RESP summer students. Congratulations to all on their excellent presentations. The award for best oral went to Sean McGrath (supervisor: Andrea Benedetti). The award for best poster went to Michelle Liang (supervisor: Anne-Marie Lauzon). See photos here (August 2017)
  • Dr. Dorival Martins, postdoctoral fellow with Dr. Dao Nguyen was interviewed by CF Canada. He and Dr. Nguyen uncovered new mechanisms that P. aeruginosa uses to escape antibiotic killing that may be targeted to improve the effectiveness of currently used drugs. Read about his project and the interview here. (July 2017)
  • Dr. Christine McCusker’s research was featured on CIHR’s Celebrating Health Researchin honor of Canada’s 150 #Canada150: Developing a molecule to help people with allergies breathe easier. (June 2017)
  • Congratulations to all our trainees this summer for the following awardsEva Kaufmannand Nargis Khan (Dr. Maziar Divangahi): FRQS postdoctoral award. Eisha Ahmed (Dr. Bruce Mazer): CIHR Undergraduate Summer Studentship Award. We also congratulations RECRU trainees. Zhiyi Lan (Dr. Dick Menzies): Master’s Award: Frederick Banting and Charles Best Canada Graduate Scholarships and FRQS Masters award. (June 2017)
  • Congratulations to our RESP researchers! Dr. Simon Rousseau received the FRQS Chercheurs-Boursiers Senior award. Dr. Marta Kaminska received the FRQS Chercheurs-Boursiers Cliniciens award – Junior 2. (June 2017)
  • The 28th annual Respiratory Research Day featured 50 oral and poster presentations. The winners for best oral presentation were: Dorival Martins (supervisor: Dr. Dao Nguyen) and Adamo Donovan (supervisor: Dr. Ben Smith). The winners for best poster presentation were: Raquel Farias (supervisor: Dr. Jean Bourbeau), Fatmah Al-Habeeb(supervisor: Dr. Carolyn Baglole), Rola Hamed (supervisor: Dr. Larry Lands), and Vanessa Moarbes (supervisor: Dr. Becky Fixman). (June 2017)
  • Dr. Sabah Hussain received the Department of Medicine Award for Excellence in Research by a Staff Member. This award is in recognition of ongoing excellence in research by a senior member of the Department of Medicine at the McGill University Health Centre. The nominee’s research program is judged on its importance, the impact of the results, the ability to obtain funding, research mentoring and research productivity. (June 2017)
  • Congratulations to Necola Guerrina (PhD student with Dr. Carolyn Baglole) who won an award for best basic research poster at the Canadian Thoracic Society meeting being help in conjunction with the American Thoracic Society meeting in Washington, DC. (May 2017)
  • Congratulations to the following CIHR Project Grants from the Fall 2016 competition: Dr. Jean Bourbeau for his grant entitled “Chronic Obstructive Pulmonary Disease categorization using cardiovascular risk and levels of inflammatory mediators: a way toward more personalized care”. (May 2017)
  • Dr. Basil Petrof has been appointed Director of the Meakins-Christie Laboratorieseffective May 15th, 2017 for a five year term. As Director of the Meakins, Dr. Petrof will be responsible for the scientific leadership and all administrative matters within the Meakins. Dr. Petrof is an accomplished and an internationally recognized scientist for his work on respiratory muscle dysfunction and sleep disordered breathing. (May 2017)
  • Necola Guerrina (supervisor: Dr. Carolyn Baglole) was interviewed and featured on the RI-MUHC Focus on Our Trainees page. Read more here. (April 2017)
  • Congratulations Dr. Larry Lands for receiving the 2017 Lifetime Achievement Award in Pediatric Respirology from the Canadian Thoracic Society. This award recognizes his significant contributions to pediatric respirology in the domains of clinical and fundamental research and support for the education of trainees. It also recognizes his exceptional leadership and dedication to patient care. (April 2017)
  • Congratulations Dr. Jean Bourbeau for receiving the 2017 CTS Distinguished Achievement Award. This award recognizes the leadership and service of individuals who have furthered the work of the CTS in respiratory health. Dr. Bourbeau is most deserving of this honor for his leadership within the Executive and Board of the CTS and in the COPD Clinical Assembly, as well as for his impact in research, academia, and clinical practice. (April 2017)
  • Dr. Larry Lands received a 2 year grant from the CF Foundation (US) for his project entitled “Rhinovirus in CF bronchial epithelial cells”. (March 2017)
  • Congratulations Necola Guerrina (supervisor: Dr. Carolyn Baglole). She placed 2nd at the McGill University 3 Minute Thesis finals (March 2017). Read more here. The top three finalists are all trainees from the RI-MUHC!
  • Necola Guerrina (supervisor: Dr. Carolyn Baglole) has moved past the first round of Heats for the McGill University 3 Minute Thesis competition. Necola will be competing at the Finals on March 15th, 2017 from 1-3pm in the Thomson House Ballroom. Way to go Necola! (March 2017)
Dr. Elizabeth Fixman and Dr. Bahar Torabi were interviewd for International Day of Women and Girls in Science
  • To mark the International Day of Women and Girls in Science, our very own Dr. Elizabeth Fixman and Dr. Bahar Torabi were interviewed by the RI-MUHC. Way to go! Read the interview here. (February 2017)
  • Congratulations to Dr. Basil Petrof on receiving a 3 year grant from CF Canada for his project entitled “Addressing Muscle Wasting in Cystic Fibrosis”. (February 2017)
  • The Meakins welcomes its newest faculty member: Dr. Ilan Azuelos.  Ilan is an Assistant Professor at McGill University and Attending Staff at the MUHC. His research aims to elucidate the molecular basis for the development and progression of pulmonary fibrosis, by examining the metabolism of fibrotic lesions in the lung. His clinical work and teaching will be based primarily at the Glen site, on the inpatient and outpatient respiratory services of the Montreal Chest Institute. (January 2017)
Pulmonary research in Canada: the Meakins-Christie Laboratories

Dr. Basil Petrof appointed Director of the Meakins-Christie Laboratories

Dr. Basil Petrof, Professor of Medicine, has been appointed Director of the Meakins-Christie Laboratories effective May 15, 2017, for a five-year term. As Director, Dr. Petrof will be responsible for the scientific leadership and administration of the Meakins-Christie Laboratories. Dr. Petrof is an accomplished and internationally recognized scientist for his work on respiratory muscle dysfunction and sleep-disordered breathing.

funding news for the Meakins-Christie Laboratories

Prognostic and therapeutic utility of human antigen R (HUR) in idiopathic pulmonary fibrosis

Dr. Carolyn Baglole was interviewed about her recent grant entitled “Prognostic and therapeutic utility of human antigen R (HUR) in idiopathic pulmonary fibrosis”. Her project received 2 year funding from Boehringer-Ingleheim’s Innovation in Understanding ILD (BUILD) program. (April 2017)

Read more here: BUILD grant breathes life into lung disease research. Supported by funding from Boehringer Ingelheim (Canada) Ltd, Carolyn Baglole hopes to unravel the mystery of idiopathic pulmonary fibrosis, a fatal lung disease that affects some 15,000 Canadians.

Pulmonary research group in Canada: the Meakins-Christie Laboratories

STAT6-IP reduces the development of allergic-type lung inflammation and airway hyperresponsiveness

Dr. Elizabeth Fixman and Dr. Brian Ward (IDIGH Program at RI-MUHC) co-authored a study in the Journal of Leukocyte Biology demonstrating that STAT6-IP reduces the development of allergic-type lung inflammation and airway hyperresponsiveness in mice re-challenged with respiratory syncytial virus (RSV). (February 2017)

Read the full press release here

Scientists discover peptide that could reduce the incidence of RSV-related asthma

New research published in the Journal of Leukocyte Biology suggests that a peptide developed to inhibit a key regulator of asthma responses reduces development of inflammation and ‘twitchy’ airways in mice

For Details: Bharat T. Srinivasa, Katherine H. Restori, Jichuan Shan, Louis Cyr, Li Xing, Soojin Lee, Brian J. Ward, and Elizabeth D. Fixman. STAT6 inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection. doi:10.1189/jlb.4A0215-062RR ; http://www.jleukbio.org/content/101/2/519.abstract

Respiratory Research Canada: Meakins-Christie Laboratories of the RI-MUHC

2016 Respiratory Research News Meakins-Christie Laboratories

  • Congratulations to Dr. Dao Nguyen for receiving the 2016 Cystic Fibrosis Research Innovation Award (junior investigator) for her research project entitled: The impact of Pseudomonas aeruginosa lasR variants on airway inflammation and CF lung disease. (November 2016)
  • Congratulations to Dr. Carolyn Baglole on receiving 2 year funding from the Boehringer-Ingleheim’s Innovation in Understanding ILD (BUILD) program for her project entitled “Prognostic and therapeutic utility of human antigen R (HUR) in idiopathic pulmonary fibrosis”. (November 2016)
  • Dr. Benoit Allard (PDF with Dr. James Martin) received a prize for best oral communicationduring the 2016 Congrès québecois en santé respiratoire (November 2016)
  • The Réseau en santé respiratoire du FRQS awarded a team grant entitled “Importance et prévention de la dysfonction diaphragmatique associée à la ventilation chez le nourrisson”. Team members include: Dr. Basil Petrof (Meakins and RESP Program), Dr. Guilherme Sant’Anna (RESP Program), Dr. Guillaume Emeriaud (St. Justine), Dr. Jean-Paul Praud (U Sherbrooke), Dr. Hugo Théôret (St. Justine), and Sylvain Morneau (St. Justine).  (November 2016)
  • Congratulations Dr. Maziar Divangahi! Together with an international consortium, he published the first Primer on Tuberculosis in Nature Reviews Disease Primers(October 2016)
  • Dr. Christine McCusker was honoured as the inaugural recipient of the Canadian Society of Allergy and Clinical Immunology’s (CSACI) F. Estelle R. Simons Award for Research (October 2016).
  • Dr. Christine McCusker spoke during the launch of the MUHC Foundation’s Discovery Club. Together with Drs. Phil Gold, Jacques Genest, Nitika Pant Pai, and the Honourable Marc Garneau, we heard about how our very own researchers are defining the future of research (October 2016).
  • Watch the video from our May 2016 Café Scientifique on Rare Respiratory Diseases. Thank you again to Michel Rochon who moderated the event flawlessly, Sarah Dettmers who shared her courageous story as a CF patient, and our experts: Dr. Jennifer Landry, Dr. Larry Lands, Dr. André Cantin, Dr. Arnold Kristof, and Dr. Simon Rousseau (October 2016).
  • Dr. Bruce Mazer was appointed Interim Executive Director and Chief Scientific Officer, RI-MUHC (October 2016).
  • The 1st Summer Student Research Day was fantastic! Congratulations to all theMeakins/RESP summer students who presented: Joyce Jang (James Martin lab), Oliver Schneider (Bruce Mazer and Christine McCusker labs), Andrea Wang(Dao Nguyen lab), Kashmira Prasade(Carolyn Baglole lab), Brandon Stopnicki (Bruce Mazer lab). (August 2016)
  • The Meakins would like to say thank youand farewell to Dr. Christina Haston. Dr. Haston joined McGill and the Meakins in 2002. She is now moving across Canada and will continue her research at the Irving K. Barber School of Arts and Sciences at UBC Okanagan. We wish you all the best! (August 2016)
  • Drs. Carolyn Baglole and Dao Nguyen have been promoted to Associate Professors with tenure at McGill University (July 2016)
  • Congratulations to all successful CIHR Project Scheme applicants. From the Meakins: Anne-Marie Lauzon for her grant entitled “Establishing the role of airway smooth muscle in human asthma and its potential as a target for therapy”. James Martin for his grant entitled “EGFR; a key pathway in immune effector responses and asthmatic airway remodeling”. Basil Petrof for his grant entitled “Novel strategies for treating respiratorymuscle failure in muscular dystrophy”. Dao Nguyen for her grant entitled “Genetic adaptation of Pseudomonas aeruginosa and lung inflammation”. Arnold Kristof for his grant (bridge funding) entitled “Targeted Therapies for Lymphangioleiomyomatosis”. We would also like to congratulate the following RECRU members on their successful grants. Faiz Ahmad Khan for his grant entitled “Computer-aided detection of pulmonary tuberculosis on digital chest x-rays: its role in the detection of active tuberculosis in a high burden setting of low HIV prevalence. John Kimoff for his grant entitled “Effects of positive airway pressure treatment of obstructive sleep-disordered breathing on maternal and fetal outcomes in hypertensive disorders of pregnancy: a pilot randomized controlled trial”. And Jean Bourbeau for his bridge funding grant with Sara Ahmed and Jacques Ricard entitled “Maximizing the effects of self-management interventions on chronic disease outcomes: implementation of a chronic disease patient health portal in primary care”. (July 2016)
  • The 27th Annual Respiratory Research Day was a success. Thank you to all the presenters for attending and presenting their research. The best poster presentation winners were: Di Xue (PhD Trainee, Supervisor: Bruce Mazer), Alice Panariti (PDF, Supervisor: James Martin & Qutayba Hamid), Guillaume Mullie (Medical Trainee, Supervisor: Kevin Schwartzman), Yukiko Sato (MSc Trainee, Supervisor: John Hanrahan). (May 2016) For pictures: Meakins Facebook (May 2016)
  • A new study by Dr. Larry Lands reinforces the importanceof implementing newborn screening for Cystic Fibrosis in Quebec (May 2016).
  • Dr. Alejandro GRASSINO 1938-2016 It is with profound sadness that we announce the passing of Dr. Alejandro Grassino on May 3, 2016. Born on April 5, 1938 in Manuel Galvez, Argentina to Luisa Rossini and Alejandro Grassino, Dr. Grassino completed his medical degree at Rosario Medical School and a fellowship at Harvard University before becoming Head of the Respiratory Division at Notre Dame Hospital, Professor of Medicine at McGill University and Université de Montreal, and Research Director at the Meakins-Christie Laboratories. Deeply dedicated to his calling as a pneumologist, Dr. Grassino was held in high esteem by colleagues, students, and patients alike while receiving many accolades for his research contributions to the specialty. He will be forever cherished by his devoted spouse of 42 years, Ilze Kraulis, his daughter Marie- Anne, his son Alexander (Renée Figlarz), and his grandchildren, Anya and Mark. He will also be fondly remembered by family in Argentina and close friends. In lieu of flowers, donations may be made to the Alzheimer Society of Montreal or to a charity held dear. (May 2016)
  • Congratulations to Jean-Philippe Leduc-Gaudet (sup: Sabah Hussain) for receiving a CIHR Doctoral Award – Frederick Banting and Charles Best Canada Graduate Scholarship (declined) and for receiving the Vanier Graduate Scholarship for three years (accepted). Congratulations to Dorival Martins (sup: Dao Nguyen) for receiving a CIHR Fellowship (April 2016)
  • Congratulations to all who received 2016/2017 FRQS Salary AwardsCarolyn Baglole (Chercheurs-Boursiers Junior 2), Sushmita Pamidi (Chercheurs-Boursiers Cliniciens Junior 1), Jason Shahin(Chercheurs-Boursiers Cliniciens Junior 1), Ilan Azuelos (Formation pour les médecins residents visant une carrière en recherche). (April 2016)
  • The 2016/2017 FRQS Awards Results are out! Congratulations to all our trainees who received funding for their projects. Masters AwardsZsombor Balassy (sup: Anne-Marie Lauzon), Bahar Torabi (sup: Bruce Mazer); Doctoral AwardsManyan Fung (sup: Arnold Kristof), Jean-Philippe Leduc-Gaudet (award declined) (sup: Sabah Hussain); PDF AwardsIsabelle Meunier (sup: Maziar Divangahi), Erwan Pernet (sup: Maziar Divangahi). (April 2016)
  • Congratulations to Drs. Carolyn Baglole and Benjamin Smith who received 2 year funding from the RI-MUHC Merck Sharp & Dohme Corp Grant Opportunities for Applications in Biomedical Research for their grant entitled “Airway Branch Patterns and Chronic Obstructive Pulmonary Disease”. This junior team is being mentored by Dr. Aimée Ryan (CHHD program). (April 2016)
  • Congratulations to Dr. Maziar Divangahi who received 2 year funding with Dr. Donald Vinh (IDIGH program) from the RI-MUHC Merck Sharp & Dohme Corp Grant Opportunities for Applications in Biomedical Research for their grant entitled “The role of CARD9 in monocyte/macrophage immunity to fungal infections”. This junior team is being mentored by Drs. Donald Sheppard, Marcel Behr, Salman Qureshi, and Irah King. (April 2016)
  • Congratulations to Dr. Simon Rousseau on receiving 3 year (2016-2019) funding from Cystic Fibrosis Canada for his grant proposal entitled “Unravelling the complexity of IL-6 signaling in CF lung disease“. (March 2016)
  • Congratulations to Jeffrey Downey (Sup: Maziar Divangahi) and Necola Guerrina (Sup: Carolyn Baglole) who tied for first place for best oral presentation at the 16th Annual McGill Biomedical Graduate Conference (AMBGC). Congratulations to Swati Pareek (Sup: Carolyn Baglole) for winning a prize for best poster presentation at the 16th AMBGC. We are proud that Meakins trainees did so well! (March 2016)
  • Congratulations to Dao Nguyen on receiving an 18 month Discovery Award from the Department of Defence entitled “Bacteria-derived small molecules as novel antimicrobial adjuvents for the treatment of nosocomial and drug-resistant bacterial infections.” (January 2016)
  • Congratulations to Dr. Christine McCuscker and her team: their work was recognized by Québec Science magazine as one of the Top 10 Discoveries of 2015. Vote for them here! (January 2016)
RI-MUHC researchers lead the first oral desensitization program in Canada

Desensitization program helps kids with milk allergies

New milk allergy research being led at the RI-MUHC. Pediatric allergy and immunology specialists Dr. Bruce Mazer and Dr. Moshe Ben-Shoshan (Montreal Children’s Hospital) started the GET-FACTS (Genetics, Environment and Therapies: Food Allergy Clinical Tolerance Studies) study in 2012.

The program is having good success with helping children with milk allergies build up tolerance to milk protein by introducing the allergen very slowly into the diet. They were interviewed by CTV, La Presse, Radio-Canada, 98,5 fm, the Gazette, CJAD and Le Devoir (September 2016).

More about the study at GET-FACTS: https://www.getfactsmilk.com/ https://www.getfactsmilk.com/

View articles and interviews about this research:

Pulmonary research group in Canada: the Meakins-Christie Laboratories

Newborn screening for Cystic Fibrosis patients

A new study led by Dr. Larry Lands was recently published in the Journal of Cystic Fibrosis 2016. The study, led by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) and Cystic Fibrosis Canada, reinforces the benefits of newborn screening for Cystic Fibrosis patients. Children with Cystic Fibrosis who are diagnosed through newborn screening are healthier and benefit more from new treatments.

About the study

The study, “The benefits of newborn screening for cystic fibrosis: The Canadian experience” was co-written by D.Y.F. Mak (Cystic Fibrosis Canada, Toronto, Canada), J. Sykes (Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Canada), A.L. Stephenson (Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Canada), and L.C. Lands (Research Institute of the McGill University Health Centre, Montreal, Canada).

This work was made possible through the in-kind support from Cystic Fibrosis Canada.

View articles and interviews about this research:

Exercise can lower the risk of muscle wasting associated with aging

Dr. Russell Hepple was interviewed by the New York Times about his work with octogenerian athlete Ed Whitlock. Dr. Hepple performed tests on Whitlock at McGill and found Whitlock has an exceptional VO2 max (54 at age 81) and a largely preserved number of motor muscle units. A study by Dr. Russell Hepple and Dr. Tanja Taivassalo that showed exercise can lower the risk of muscle wasting associated with aging was also featured in the New York Times (Dec and Mar 2016).