New this year, we will be organizing a joint RESP JOURNAL CLUB with RECRU and Meakins members. This journal club is open to all clinical and research faculty, trainees, fellows, and residents. The goal of this journal club is to critically evaluate a research article (or topic) from both clinical and fundamental science perspectives. Publications will be jointly chosen by RECRU and Meakins faculty members, who will facilitate discussion of the article. The publications will cover the various research themes of the RESP program, with a focus on translational research. Presentations will be delivered by faculty and/or trainees/fellows and all discussions will be moderated. Articles will be distributed 1 week in advance of the Journal Club date.
Frequency: Monthly on Fridays at 12 noon via ZOOM
|Date||RECRU Moderator||Meakins moderator||topic & article|
|Friday September 18, 2020||Benjamin Smith||Simon Rousseau||Early-onset emphysema in a large French-Canadian family: a genetic investigation|
Lancet Respir Med. 2019 May;7(5):427-436.
|Friday October 16, 2020||Sushmita Pamidi||Basil Petrof||Sleep modulates haematopoiesis and protects against atherosclerosis|
Nature. 2019 Feb;566(7744):383-387
Symptom Subtypes of Obstructive Sleep Apnea Predict Incidence of Cardiovascular Outcomes
Am J Respir Crit Care Med. 2019 Aug 15;200(4):493-506.
|Friday November 20, 2020||John Kimoff||Carolyn Baglole||Factors associated with COVID-19-related death using OpenSAFELY|
Nature 584, 430–436 (2020)
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV2 Receptor ACE2 in the Respiratory Tract
Dev Cell 2020 Jun 8;53(5):514-529.e3
|Friday December 11, 2020||TBC|
|Friday January 15, 2021||DATE TBC|
|Friday February 12, 2021||TBC|
|Friday March 19, 2021||TBC|
|Friday April 16, 2021||TBC|
|Friday May 14, 2021||TBC|
|Friday June 11, 2021||TBC|
Checklist and questions for presenters to integrate into their presentation and to use for moderating the discussion:
|What is the stated rationale/motivation for this study?||Is this an important clinical/scientific problem?|
|What is the stated hypothesis (or objective)?||Does the hypothesis (or objective) address the stated rationale)?|
|What are the stated methods used to test the hypothesis (achieve the objective)?||Will the methods test the stated hypothesis?|
|What are the results?||Are the results presented appropriately?|
|What is the authors’ interpretation of the results?||Do you agree with their interpretation?|
Are they making inferences that go beyond what the data show?
(If a clinical study) Do the findings apply to our patient population?
(If an interventional clinical study) Is the effect size clinically meaningful?
|What are the stated limitations of the study?||Do you agree with the stated limitations? |
Are there other limitations?
|Does this study provide the definitive answer the original problem? |
Are other studies needed?
RECRU seminars: Fridays at 1pm
|October 2, 2020||Sushmita Pamidi|
|October 23, 2020||Benjamin Smith|
|November 6, 2020||Deborah Assayag|
|December 18, 2020||Tania Janaudis-Ferreira|
|January 29, 2021||Grant Presentations|
|February 19, 2021||Anne Gonzalez|
|March 26, 2021||John Kimoff|
|April 30, 2021||Marta Kaminska|
|May 28, 2021||Faiz Ahmad Khan|
|June 18, 2021||Kevin Schwartzman|