The focus of our research is to understand how immune cells communicate with their local environment to promote protective immune responses relevant to human disease. We are particularly interested in immunity at barrier sites such as the gut, skin and lung as these tissues face the complex task of maintaining homeostasis while directly interacting with the outside world.
Ongoing studies include:
- The molecular mechanisms of CD4+ T cell differentiation following intestinal helminth infection.
- The gut-lung axis in the context of infectious disease
- Innate immune mechanisms of disease tolerance during intestinal helminth infection.
- Regulation of skin-resident IL-17-producing T cells in the context of psoriatic-like inflammation.
- The impact of bacteriophages on innate immunity and inflammatory bowel diseases.
Check out this link to find out why parasites may be critical for human evolution!
This link describes how helminths can affect human fertility.
Vulnerability of the host to Mycobacterium tuberculosis infection is due to a compromised gut microbiota
RI-MUHC, Block E
1001 Decarie Blvd.
Montreal QC H4A 3J1
Tel: 514-934-1934 Ext. 35260 (lab)
Tel: 514-934-1934 Ext. 76185 (office)
Tel: 514-934-1934 Ext. 76172 (admin)
Education & Training
BA (Psychology), Ohio University, 2000
MSc (Physical Therapy), U Pittsburgh, 2002
PhD (Immunology), U Rochester, 2008
PDF Trudeau Institute, 2012