Publications

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Pulmonary research publications from the Meakins-Christie Laboratories and other members of the RI-MUHC RESP Program are shown.
Publications are organized by date that notification was received from PubMed.

For press releases and news articles about our publications, please go here: https://www.meakinsmcgill.com/category/publications/

September 2019

Janice Sánchez B, Tremblay AK, Leduc-Gaudet JP, Hall DT, Kovacs E, Ma JF, Mubaid S, Hallauer PL, Phillips BL, Vest KE, Corbett AH, Kontoyiannis DL, Hussain SNA, Hastings KEM, Di Marco S, Gallouzi IE. Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy. Nat Commun. 2019 Sep 13;10(1):4171. doi: 10.1038/s41467-019-12186-6. PMID: 31519904 [PubMed – in process]

Gagné M, Lauzier S, Babineau-Therrien J, Hamel C, Penney SE, Bourbeau J, Moisan J, Boulet LP. COPD-Specific Self-Management Support Provided by Trained Educators in Everyday Practice is Associated with Improved Quality of Life, Health-Directed Behaviors, and Skill and Technique Acquisition: A Convergent Embedded Mixed-Methods Study. Patient. 2019 Sep 10. doi: 10.1007/s40271-019-00386-7. [Epub ahead of print] PMID: 31502238 [PubMed – as supplied by publisher]

Lands LC, Stanojevic S. Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis. Cochrane Database Syst Rev. 2019 Sep 9;9:CD001505. doi: 10.1002/14651858.CD001505.pub5. [Epub ahead of print] Review.

Ramakrishnan RK, Al Heialy S, Hamid Q. Role of IL-17 in asthma pathogenesis and its implications for the clinic. Expert Rev Respir Med. 2019 Sep 9. doi: 10.1080/17476348.2019.1666002. [Epub ahead of print] PMID: 31498708 [PubMed – as supplied by publisher]

Jang JH, Panariti A, O’Sullivan MJ, Pyrch M, Wong C, Lauzon AM, Martin JG. Characterization of Cystic Fibrosis Airway Smooth Muscle Cell Proliferative and Contractile Activities. Am J Physiol Lung Cell Mol Physiol. 2019 Sep 11. doi: 10.1152/ajplung.00090.2019. [Epub ahead of print] PMID: 31508974 [PubMed – as supplied by publisher] PMID: 31499593 [PubMed – as supplied by publisher]

Lundblad LK, Siddiqui s, Bossé Y, Dandurand RJ, Applications of oscillometry in clinical research and practice. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 2019 Sep; DOI: 10.1080/24745332.2019.1649607

Janaudis-Ferreira T, Mathur S, Deliva R, Howes N, Patterson C, Räkel A, So S, Wickerson L, White M, Avitzur Y, Johnston O, Heywood N, Singh S, Holdsworth S. Exercise for Solid Organ Transplant Candidates and Recipients: A Joint Position Statement of the Canadian Society of Transplantation and CAN-RESTORE. Transplantation. 2019 Sep;103(9):e220-e238. doi: 10.1097/TP.0000000000002806. PMID: 31461743 [PubMed – in process]

August 2019

Marcolefas E, Leung T, Okshevsky M, McKay G, Hignett E, Hamel J, Aguirre G, Blenner-Hassett O, Boyle B, Lévesque RC, Nguyen D, Gruenheid S, Whyte L. Culture-Dependent Bioprospecting of Bacterial Isolates From the Canadian High Arctic Displaying Antibacterial Activity. Front Microbiol. 2019 Aug 9;10:1836. doi: 10.3389/fmicb.2019.01836. eCollection 2019. PMID: 31447822 [PubMed] Free PMC Article

Burks AC, Gould MK, Silvestri G, Yarmus LB, Sears CR, Arenberg DA, Gonzalez AV, Slatore CG, Tanner NT, Vachani A, Nana-Sinkam P, Fuster MM, Wahidi MM, Tanoue LT, Rivera MP. Ann Am Thorac Soc. 2019 Aug 22. doi: 10.1513/AnnalsATS.201905-389PS. [Epub ahead of print] No abstract available. PMID: 31437410 [PubMed – as supplied by publisher]

Wang M, Aaron CP, Madrigano J, Hoffman EA, Angelini E, Yang J, Laine A, Vetterli TM, Kinney PL, Sampson PD, Sheppard LE, Szpiro AA, Adar SD, Kirwa K, Smith B, Lederer DJ, Diez-Roux AV, Vedal S, Kaufman JD, Barr RG. Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function. JAMA. 2019 Aug 13;322(6):546-556. doi: 10.1001/jama.2019.10255. PMID: 31408135 [PubMed – indexed for MEDLINE]

Lundblad LKA, Miletic R, Piitulainen E, Wollmer P. Oscillometry in Chronic Obstructive Lung Disease: In vitro and in vivo evaluation of the impulse oscillometry and tremoflo devices. Sci Rep. 2019 Aug 12;9(1):11618. doi: 10.1038/s41598-019-48039-x.

Gagnon S, Ross B, Bourbeau J. Video Telehealth and Pulmonary Rehabilitation : Need for a Better Understanding. Am J Respir Crit Care Med. 2019 Aug 6. doi: 10.1164/rccm.201907-1394LE. [Epub ahead of print] No abstract available. PMID: 31386815 [PubMed – as supplied by publisher]

Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Goodwin-Wilson M, Jiang HY, Bourdeau F, Beauchamp A, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE. Gram-Negative Pneumonia Augments Non-Small Cell Lung Cancer Metastasis Through Host Toll-like Receptor 4 Activation. J Thorac Oncol. 2019 Aug 2. pii: S1556-0864(19)30653-7. doi: 10.1016/j.jtho.2019.07.023. [Epub ahead of print] PMID: 31382038 [PubMed – as supplied by publisher]

Mokhlesi B, Masa JF, Brozek JL, Gurubhagavatula I, Murphy PB, Piper AJ, Tulaimat A, Afshar M, Balachandran JS, Dweik RA, Grunstein RR, Hart N, Kaw R, Lorenzi-Filho G, Pamidi S, Patel BK, Patil SP, Pépin JL, Soghier I, Tamae Kakazu M, Teodorescu M. Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2019 Aug 1;200(3):e6-e24. doi: 10.1164/rccm.201905-1071ST. PMID: 31368798 [PubMed – in process]

July 2019

Trepanier M, Paradis T, Kouyoumdjian A, Dumitra T, Charlebois P, Stein BS, Liberman AS, Schwartzman K, Carli F, Fried GM, Feldman LS, Lee L. The Impact of Delays to Definitive Surgical Care on Survival in Colorectal Cancer Patients. J Gastrointest Surg. 2019 Jul 31. doi: 10.1007/s11605-019-04328-4. [Epub ahead of print] PMID: 31367895 [PubMed – as supplied by publisher]

Salmon C, Conus F, Parent MÉ, Benedetti A, Rousseau MC. Association between Bacillus Calmette-Guérin vaccination and lymphoma: a population-based birth cohort study. J Intern Med. 2019 Jul 30. doi: 10.1111/joim.12965. [Epub ahead of print] PMID: 31361936 [PubMed – as supplied by publisher]

Trajman A, Wakoff-Pereira MF, Ramos-Silva J, Cordeiro-Santos M, Militão de Albuquerque MF, Hill PC, Menzies D. Knowledge, attitudes and practices on tuberculosis transmission and prevention among auxiliary healthcare professionals in three Brazilian high-burden cities: a cross-sectional survey. BMC Health Serv Res. 2019 Jul 30;19(1):532. doi: 10.1186/s12913-019-4231-x. PMID: 31362728 [PubMed – in process] Free Article

Rayes RF, Mouhanna JG, Nicolau I, Bourdeau F, Giannias B, Rousseau S, Quail D, Walsh L, Sangwan V, Bertos N, Cools-Lartigue J, Ferri LE, Spicer JD. Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects. JCI Insight. 2019 Jul 25;5. pii: 128008. doi: 10.1172/jci.insight.128008. PMID: 31343990 [PubMed – in process] Free Article

Abdallah SJ, Jensen D, Lewthwaite H. Updates in opioid and nonopioid treatment for chronic breathlessness. Curr Opin Support Palliat Care. 2019 Jul 22. doi: 10.1097/SPC.0000000000000449. [Epub ahead of print] PMID: 31335450 [PubMed – as supplied by publisher]

Skopelja-Gardner S, Theprungsirikul J, Lewis KA, Hammond JH, Carlson KM, Hazlett HF, Nymon A, Nguyen D, Berwin BL, Hogan DA, Rigby WFC. Regulation of Pseudomonas aeruginosa-Mediated Neutrophil Extracellular Traps. Front Immunol. 2019 Jul 18;10:1670. doi: 10.3389/fimmu.2019.01670. eCollection 2019. PMID: 31379861 [PubMed – in process] Free PMC Article

Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD Jr, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O’Neal W, Paine R 3rd, Rennard SI, Smith BM, Woodruff PG, Lin CL. Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS). Respir Res. 2019 Jul 15;20(1):153. doi: 10.1186/s12931-019-1121-z. PMID: 31307479 [PubMed – in process]

Wu Y, Levis B, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Boruff J, Cuijpers P, Gilbody S, Ioannidis JPA, Kloda LA, McMillan D, Patten SB, Shrier I, Ziegelstein RC, Akena DH, Arroll B, Ayalon L, Baradaran HR, Baron M, Bombardier CH, Butterworth P, Carter G, Chagas MH, Chan JCN, Cholera R, Conwell Y, de Man-van Ginkel JM, Fann JR, Fischer FH, Fung D, Gelaye B, Goodyear-Smith F, Greeno CG, Hall BJ, Harrison PA, Härter M, Hegerl U, Hides L, Hobfoll SE, Hudson M, Hyphantis T, Inagaki MD, Jetté N, Khamseh ME, Kiely KM, Kwan Y, Lamers F, Liu SI, Lotrakul M, Loureiro SR, Löwe B, McGuire A, Mohd-Sidik S, Munhoz TN, Muramatsu K, Osório FL, Patel V, Pence BW, Persoons P, Picardi A, Reuter K, Rooney AG, Santos IS, Shaaban J, Sidebottom A, Simning A, Stafford MD, Sung S, Tan PLL, Turner A, van Weert HC, White J, Whooley MA, Winkley K, Yamada M, Benedetti A, Thombs BD. Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis. Psychol Med. 2019 Jul 12:1-13. doi: 10.1017/S0033291719001314. [Epub ahead of print]. PMID: 31298180 [PubMed – as supplied by publisher]

Kendzerska T, Aaron SD, To T, Licskai C, Stanbrook M, Vozoris N, Hogan ME, Tan WC, Bourbeau J, Gershon AS; Canadian Respiratory Research Network. Effectiveness and Safety of Inhaled Corticosteroids in Older Individuals with COPD and/or Asthma: A Population Study. Ann Am Thorac Soc. 2019 Jul 12. doi: 10.1513/AnnalsATS.201902-126OC. [Epub ahead of print]. PMID: 31298938 [PubMed – as supplied by publisher]

Kanbar LE, Shalish W, Latremouille S, Rao S, Brown KA, Kearney RE, Sant’Anna GM. Cardiorespiratory behavior of preterm infants receiving continuous positive airway pressure and high flow nasal cannula post extubation: randomized crossover study. Pediatr Res. 2019 Jul 5. doi: 10.1038/s41390-019-0494-5. [Epub ahead of print] PMID: 31277077 [PubMed – as supplied by publisher]

Abdel-Nour M, Carneiro LAM, Downey J, Tsalikis J, Outlioua A, Prescott D, Da Costa LS, Hovingh ES, Farahvash A, Gaudet RG, Molinaro R, van Dalen R, Lau CCY, Azimi FC, Escalante NK, Trotman-Grant A, Lee JE, Gray-Owen SD, Divangahi M, Chen JJ, Philpott DJ, Arnoult D, Girardin SE. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science. 2019 Jul 5;365(6448). pii: eaaw4144. doi: 10.1126/science.aaw4144. PMID: 31273097 [PubMed – in process]

Lewthwaite H, Koch EM, Tracey L, Jensen D. Standardized measurement of breathlessness during exercise. Curr Opin Support Palliat Care. 2019 Jul 1. doi: 10.1097/SPC.0000000000000443. [Epub ahead of print] PMID: 31268873 [PubMed – as supplied by publisher]

June 2019

Kristof AS, Ortega VE. The discovery of novel mechanisms for lymphangioleiomyomatosis pathogenesis through GWAS: a rarity in rare respiratory disorders. Eur Respir J. 2019 Jun 27;53(6). pii: 1900863. doi: 10.1183/13993003.00863-2019. Print 2019 Jun. No abstract available. PMID: 31249011 [PubMed – in process]

Martins D, Nguyen D, English AM. Ctt1 catalase activity potentiates antifungal azoles in the emerging opportunistic pathogen Saccharomyces cerevisiae. Sci Rep. 2019 Jun 24;9(1):9185. doi: 10.1038/s41598-019-45070-w. PMID: 31235707 [PubMed – in process] Free Article

Salahuddin S, Thomson E, Méziane O, Farnos O, Pagliuzza A, Chomont N, Olivenstein R, Costiniuk C, Jenabian MA. Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment. J Vis Exp. 2019 Jun 23;(148). doi: 10.3791/59427. PMID: 31282892 [PubMed – in process]

Wilder-Smith A, Wei Y, Araújo TVB, VanKerkhove M, Turchi Martelli CM, Turchi MD, Teixeira M, Tami A, Souza J, Sousa P, Soriano-Arandes A, Soria-Segarra C, Sanchez Clemente N, Rosenberger KD, Reveiz L, Prata-Barbosa A, Pomar L, Pelá Rosado LE, Perez F, Passos SD, Nogueira M, Noel TP, Moura da Silva A, Moreira ME, Morales I, Miranda Montoya MC, Miranda-Filho DB, Maxwell L, Macpherson CNL, Low N, Lan Z, LaBeaud AD, Koopmans M, Kim C, João E, Jaenisch T, Hofer CB, Gustafson P, Gérardin P, Ganz JS, Dias ACF, Elias V, Duarte G, Debray TPA, Cafferata ML, Buekens P, Broutet N, Brickley EB, Brasil P, Brant F, Bethencourt S, Benedetti A, Avelino-Silva VL, Ximenes RAA, Alves da Cunha A, Alger J; Zika Virus Individual Participant Data Consortium.  Understanding the relation between Zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual participant data meta-analysis of longitudinal studies of pregnant women and their infants and children. BMJ Open. 2019 Jun 18;9(6):e026092. doi: 10.1136/bmjopen-2018-026092. PMID: 31217315 [PubMed – in process] Free Article

Salem D, Subang R, Divangahi M, Pernet E, Pineau C, Cayrol R, Levine JS, Rauch J. Necroptotic cell binding of β2-glycoprotein I provides a potential autoantigenic stimulus in systemic lupus erythematosus. Immunol Cell Biol. 2019 Jun 12. doi: 10.1111/imcb.12279. [Epub ahead of print] PMID: 31187539 [PubMed – as supplied by publisher]

Memari B, Nguyen-Yamamoto L, Salehi-Tabar R, Zago M, Fritz JH, Baglole CJ, Goltzman D, White JH. Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light. Sci Rep. 2019 Jun 11;9(1):8486. doi: 10.1038/s41598-019-44862-4. PMID: 31186463 [PubMed – in process] Free Article

Farias R, Sedeno M, Beaucage D, Drouin I, Ouellet I, Joubert A, Abimaroun R, Patel M, Abou Rjeili M, Bourbeau J. Innovating the treatment of COPD exacerbations: a phone interactive telesystem to increase COPD Action Plan adherence. BMJ Open Respir Res. 2019 Apr 9;6(1):e000379. doi: 10.1136/bmjresp-2018-000379. eCollection 2019. PMID: 31178998 [PubMed] Free PMC Article

Hanrahan JW, Sato Y, Carlile GW, Jansen G, Young JC, Thomas DY. Cystic Fibrosis: Proteostatic correctors of CFTR trafficking and alternative therapeutic targets. Expert Opin Ther Targets. 2019 Jun 6. doi: 10.1080/14728222.2019.1628948. [Epub ahead of print]

Krishnan JA, Nibber A, Chisholm A, Price D, Bateman ED, Bjermer L, van Boven JF, Brusselle G, Costello RW, Dandurand RJ, Diamant Z, Van Ganse E, Gouder C, van Kampen SC, Kaplan A, Kocks J, Miravitlles M, Niimi A, Pizzichini E, Rhee CK, Soriano JB, Vogelmeier C, Román-Rodriguez M, Carter V, Roche N. Prevalence and Characteristics of Asthma-COPD Overlap in Routine Primary Care Practices. Ann Am Thorac Soc. 2019 Jun 4. doi: 10.1513/AnnalsATS.201809-607OC. [Epub ahead of print] PMID: 31162945 [PubMed – as supplied by publisher]

Campbell JR, Dowdy D, Schwartzman K. Treatment of latent infection to achieve tuberculosis elimination in low-incidence countries. PLoS Med. 2019 Jun 6;16(6):e1002824. doi: 10.1371/journal.pmed.1002824. eCollection 2019 Jun. PMID: 31170161 [PubMed – in process] Free Article

May 2019

Shorofsky M, Bourbeau J, Kimoff J, Jen R, Malhotra A, Ayas N, Tan WC, Aaron SD, Sin DD, Road J, Chapman KR, O’Donnell DE, Maltais F, Hernandez P, Walker BL, Marciniuk D, Kaminska M., Impaired Sleep Quality in COPD is Associated with Exacerbations: The CanCOLD cohort study. Respiratory Research Network and the CanCOLD Collaborative Research group. Chest. 2019 May 28. pii: S0012-3692(19)31121-3. doi: 10.1016/j.chest.2019.04.132. [Epub ahead of print]

Farahnak S, Simon L, McGovern TK, Chen M, Khazaei N, Martin JG. HB-EGF Synthesized by CD4 T Cells Modulates Allergic Airway Eosinophilia by Regulating IL-5 Synthesis. J Immunol. 2019 May 24. pii: ji1801686. doi: 10.4049/jimmunol.1801686. [Epub ahead of print] PMID: 31127030 [PubMed – as supplied by publisher]

McGovern TK, Farahnak S, Chen M, Larsson K, Martin JG, Adner M. Organic dust, causing both oxidative stress and Nrf2 activation, is phagocytized by bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2019 May 22. doi: 10.1152/ajplung.00377.2018. [Epub ahead of print]
PMID: 31116579 [PubMed – as supplied by publisher]

Selvarajah B, Azuelos I, Platé M, Guillotin D, Forty EJ, Contento G, Woodcock HV, Redding M, Taylor A, Brunori G, Durrenberger PF, Ronzoni R, Blanchard AD, Mercer PF, Anastasiou D, Chambers RC. mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis. Sci Signal. 2019 May 21;12(582). pii: eaav3048. doi: 10.1126/scisignal.aav3048. PMID: 31113850 [PubMed – in process]

Pernet E, Downey J, Vinh DC, Powell WS, Divangahi M. Leukotriene B4-type I interferon axis regulates macrophage-mediated disease tolerance to influenza infection. Nat Microbiol. 2019 May 20. doi: 10.1038/s41564-019-0444-3. [Epub ahead of print] PMID: 31110361 [PubMed – as supplied by publisher]

Janaudis-Ferreira T, Tansey CM, Harrison SL, Beaurepaire CE, Goodridge D, Bourbeau J, Baltzan M. Setting the Stage for More Acceptable Pulmonary Rehabilitation Post-Acute Exacerbation of COPD. Ann Am Thorac Soc. 2019 May 15. doi: 10.1513/AnnalsATS.201812-854OC. [Epub ahead of print] PMID: 31091963 [PubMed – as supplied by publisher]

Walker IF, Shi O, Hicks J, Elsey H, Wei X, Menzies D, Lan Z, Falzon D, Migliori GB, Pérez-Guzmán C, Vargas MH, García-García L, Sifuentes Osornio J, Ponce-De-León A, van der Walt M, Newell JN. Analysis of loss to follow up in 4,099 multidrug-resistant pulmonary tuberculosis patients. Eur Respir J. 2019 May 9. pii: 1800353. doi: 10.1183/13993003.00353-2018. [Epub ahead of print] PMID: 31073080 [PubMed – as supplied by publisher]

Abdallah SJ, Faull OK, Wanigasekera V, Finnegan SL, Jensen D, Pattinson K. Opioids for breathlessness: Psychological and neural factors influencing response variability. Eur Respir J. 2019 May 9. pii: 1900275. doi: 10.1183/13993003.00275-2019. [Epub ahead of print] No abstract available. PMID: 31073088 [PubMed – as supplied by publisher]

Abu-Arish A, Pandžić E, Kim D, Tseng HW, Wiseman PW, Hanrahan JW. Agonists that stimulate secretion promote the recruitment of CFTR into membrane lipid microdomains. J Gen Physiol. 2019 May 2. pii: jgp.201812143. doi: 10.1085/jgp.201812143. [Epub ahead of print] PMID: 31048413 [PubMed – as supplied by publisher]

Zhao H, Moarbes V, Gaudreault V, Shan J, Aldossary H, Cyr L, Fixman ED. Sex Differences in IL-33-Induced STAT6-Dependent Type 2 Airway Inflammation. Front Immunol. 2019 May 1;10:859. doi: 10.3389/fimmu.2019.00859. eCollection 2019. PMID: 31118931 [PubMed – in process]

April 2019

Oga-Omenka C, Zarowsky C, Agbaje A, Kuye J, Menzies D.Rates and timeliness of treatment initiation among drug-resistant tuberculosis patients in Nigeria- A retrospective cohort study. PLoS One. 2019 Apr 25;14(4):e0215542. doi: 10.1371/journal.pone.0215542. eCollection 2019.
PMID: 31022228 [PubMed – in process]

Alghamdi SM, Janaudis-Ferreira T, Alhasani R, Ahmed S. Acceptance, adherence and dropout rates of individuals with COPD approached in telehealth interventions: a protocol for systematic review and meta-analysis. BMJ Open. 2019 Apr 25;9(4):e026794. doi: 10.1136/bmjopen-2018-026794. PMID: 31028042 [PubMed – in process]

Ke D, Kitamura Y, Lejtenyi D, Mazer B, Brouillette RT, Brown K. Enhanced interleukin-8 production in mononuclear cells in severe pediatric obstructive sleep apnea. Allergy Asthma Clin Immunol. 2019 Apr 16;15:23. doi: 10.1186/s13223-019-0338-1. eCollection 2019.
PMID: 31015845 [PubMed]

Moayedi-Nia S, Barss L, Oxlade O, Valiquette C, Ly MX, Campbell JR, Lan Z, Nsengiyumva P, Fregonese F, Lisboa Bastos M, Sampath D, Winters N, Menzies D.The mTST – An mHealth approach for training and quality assurance of tuberculin skin test administration and reading. PLoS One. 2019 Apr 17;14(4):e0215240. doi: 10.1371/journal.pone.0215240. eCollection 2019. PMID: 30995275 [PubMed – in process]

Liang F, Emeriaud G, Rassier DE, Shang D, Gusev E, Hussain SNA, Sage M, Crulli B, Fortin-Pellerin E, Praud JP, Petrof BJ. Mechanical ventilation causes diaphragm dysfunction in newborn lambs. Crit Care. 2019 Apr 16;23(1):123. doi: 10.1186/s13054-019-2409-6.
PMID: 30992039 [PubMed – in process]

Bossé Y, Lamontagne M, Gaudreault N, Racine C, Levesque MH, Smith BM, Auger D, Clemenceau A, Paré MÈ, Laviolette L, Tremblay V, Maranda B, Morissette MC, Maltais F. Early-onset emphysema in a large French-Canadian family: a genetic investigation. Lancet Respir Med. 2019 Apr 15. pii: S2213-2600(19)30056-6. doi: 10.1016/S2213-2600(19)30056-6. [Epub ahead of print] PMID: 31000475 [PubMed – as supplied by publisher]

Mukherjee M, Kjarsgaard M, Radford K, Huang C, Leigh R, Dorscheid DR, Lemiere C, Boulet LP, Waserman S, Martin J, Nair P. Omalizumab in patients with severe asthma and persistent sputum eosinophilia. Allergy Asthma Clin Immunol. 2019 Apr 3;15:21. doi: 10.1186/s13223-019-0337-2. eCollection 2019. PMID: 30988677 [PubMed]

Ojanguren I, Chaboillez S, Cloutier Y, Panariti A, McGovern TK, Martin JG, Lemiere C. Impact of low dose chlorine inhalation in healthy humans: a pilot study. J Investig Allergol Clin Immunol. 2019 Apr 8:0. doi: 10.18176/jiaci.0396. [Epub ahead of print] No abstract available. PMID: 30957763 [PubMed – as supplied by publisher]

Ichikawa T, Panariti A, Audusseau S, Mogas AK, Olivenstein R, Chakir J, Laviolette M, Allakhverdi Z, Al Heialy S, Martin JG, Hamid Q.Effect of bronchial thermoplasty on structural changes and inflammatory mediators in the airways of subjects with severe asthma. Respir Med. 2019 Apr;150:165-172. doi: 10.1016/j.rmed.2019.03.005. Epub 2019 Mar 20. PMID: 30961946 [PubMed – in process]

Ijpma G, Balassy Z, Lauzon AM. Rapid time-stamped analysis of filament motility. J Muscle Res Cell Motil. 2019 Apr 10. doi: 10.1007/s10974-019-09503-3. [Epub ahead of print] PMID: 30972524 [PubMed – as supplied by publisher]

Harty CE, Martins D, Doing G, Mould DL, Clay ME, Occhipinti P, Nguyen D, Hogan DA. Ethanol stimulates trehalose production through a SpoT-DksA-AlgU dependent pathway in Pseudomonas aeruginosa. J Bacteriol. 2019 Apr 1. pii: JB.00794-18. doi: 10.1128/JB.00794-18. [Epub ahead of print] PMID: 30936375 [PubMed – as supplied by publisher]

Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Allard C, Barbeau J, Cantin A, Charette SJ, Déziel E, Malouin F, Milot J, Nguyen D, Popa C, Boyle B, Levesque RC. The Pseudomonas aeruginosa population among Cystic Fibrosis patients in Quebec, Canada: a disease hotspot without known epidemic isolates. J Clin Microbiol. 2019 Apr 3. pii: JCM.02019-18. doi: 10.1128/JCM.02019-18. [Epub ahead of print] PMID: 30944192 [PubMed – as supplied by publisher]

March 2019

Bourbeau J, Granados D, Roze S, Durand-Zaleski I, Casan P, Köhler D, Tognella S, Viejo JL, Dal Negro RW, Kessler R. Cost-effectiveness of the COPD Patient Management European Trial home-based disease management program. Int J Chron Obstruct Pulmon Dis. 2019 Mar 14;14:645-657. doi: 10.2147/COPD.S173057. eCollection 2019. PMID: 30936689 [PubMed – in process]

Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine Iii R, Han MK, Cooper C, Dransfield MT, Criner G, Krishnan JA, Bowler R, Bleecker ER, Peters S, Rich SS, Meyers DA, Rotter JI, Barr RG. A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography. Am J Respir Crit Care Med. 2019 Mar 29. doi: 10.1164/rccm.201812-2355OC. [Epub ahead of print]

Farahnak S, Chronopoulos J, Martin JG. Nucleic Acid Sensing in Allergic Disorders. Int Rev Cell Mol Biol. 2019;345:1-33. doi: 10.1016/bs.ircmb.2018.11.001.

Oxlade O, Trajman A, Benedetti A, Adjobimey M, Cook VJ, Fisher D, Fox GJ, Fregonese F, Hadisoemarto P, Hill PC, Johnston J, Long R, Obeng J, Ruslami R, Valiquette C, Menzies D. Enhancing the public health impact of latent tuberculosis infection diagnosis and treatment (ACT4): protocol for a cluster randomised trial. BMJ Open. 2019 Mar 20;9(3):e025831. doi: 10.1136/bmjopen-2018-025831.

Alvarez F, Istomine R, Shourian M, Pavey N, Al-Aubodah TA, Qureshi S, Fritz JH, Piccirillo CA. The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3+ regulatory T cells during mucosal inflammation. Mucosal Immunol. 2019 Mar 11. doi: 10.1038/s41385-019-0153-5. [Epub ahead of print]

Ronald LA, Campbell JR, Rose C, Balshaw R, Romanowski K, Roth D, Marra F, Schwartzman K, Cook VJ, Johnston JC. Estimated impact of World Health Organization latent tuberculosis screening guidelines in a low TB incidence region: retrospective cohort study. Clin Infect Dis. 2019 Mar 11. pii: ciz188. doi: 10.1093/cid/ciz188. [Epub ahead of print]

Sonjak V, Jacob KJ, Spendiff S, Vuda M, Perez A, Miguez K, Minozzo FC, Spake C, Morais JA, Hepple RT. Reduced Mitochondrial Content, Elevated ROS, and Modulation by Denervation in Skeletal Muscle of Pre-frail/Frail Elderly Women. J Gerontol A Biol Sci Med Sci. 2019 Mar 11. pii: glz066. doi: 10.1093/gerona/glz066. [Epub ahead of print]

Long R, Asadi L, Heffernan C, Barrie J, Winter C, Egedahl ML, Paulsen C, Kunimoto B, Menzies D. Is there a fundamental flaw in Canada’s post-arrival immigrant surveillance system for tuberculosis? PLoS One. 2019 Mar 8;14(3):e0212706. doi: 10.1371/journal.pone.0212706. eCollection 2019.

Murugapoopathy V, McCusker C, Gupta IR. The pathogenesis and management of renal scarring in children with vesicoureteric reflux and pyelonephritis. Pediatr Nephrol. 2019 Mar 7. doi: 10.1007/s00467-018-4187-9. [Epub ahead of print] Review.

Singh D, Agusti A, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Criner GJ, Frith P, Halpin DMG, Han M, López Varela MV, Martinez F, Montes de Oca M, Papi A, Pavord ID, Roche N, Sin DD, Stockley R, Vestbo J, Wedzicha JA, Vogelmeier C. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The GOLD Science Committee Report 2019. Eur Respir J. 2019 Mar 7. pii: 1900164. doi: 10.1183/13993003.00164-2019. [Epub ahead of print] Review.

February 2019

Khan N, Mendonca L, Dhariwal A, Fontes G, Menzies D, Xia J, Divangahi M, King IL. Intestinal dysbiosis compromises alveolar macrophage immunity to Mycobacterium tuberculosis. Mucosal Immunol. 2019 Feb 19. doi: 10.1038/s41385-019-0147-3. [Epub ahead of print]

Apriani L, McAllister S, Sharples K, Alisjahbana B, Ruslami R, Hill PC, Menzies D. Latent tuberculosis infection in health care workers in low and middle-income countries: an updated systematic review. Eur Respir J. 2019 Feb 20. pii: 1801789. doi: 10.1183/13993003.01789-2018. [Epub ahead of print]

Latremouille S, Shalish W, Kanbar L, Lamer P, Rao S, Kearney RE, Sant’Anna GM. The effects of nasal continuous positive airway pressure and high flow nasal cannula on heart rate variability in extremely preterm infants after extubation: A randomized crossover trial. Pediatr Pulmonol. 2019 Feb 27. doi: 10.1002/ppul.24284. [Epub ahead of print]

De Schryver S, Mazer B, Clarke A, St Pierre Y, Lejtneyi D, Langlois A, Torabi B, Zhao WW, Chan ES, Baerg I, Ben-Shoshan M. Adverse events in oral immunotherapy for the desensitization of cow’s milk allergy in children: a randomized controlled trial. J Allergy Clin Immunol Pract. 2019 Feb 15. pii: S2213-2198(19)30171-0. doi: 10.1016/j.jaip.2019.02.007. [Epub ahead of print]

Abdallah SJ, Smith BM, Bourbeau J, Jensen DReply: Ethics of Health Research Supported by For-Profit Cannabis Companies: What Have We Learned from Big Tobacco? Ann Am Thorac Soc. 2019 Feb 2. doi: 10.1513/AnnalsATS.201812-850LE. [Epub ahead of print] No abstract available.

N’Diaye DS, Nsengiyumva NP, Uppal A, Oxlade O, Alvarez GG, Schwartzman KThe potential impact and cost-effectiveness of tobacco reduction strategies for tuberculosis prevention in Canadian Inuit communities. BMC Med. 2019 Feb 4;17(1):26. doi: 10.1186/s12916-019-1261-5.

Patil SP, Ayappa IA, Caples SM, Kimoff RJ, Patel SR, Harrod CG. Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment. J Clin Sleep Med. 2019 Feb 4. pii: jc-18-00760. [Epub ahead of print]

Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S. SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1.

Press VG, Au DH, Bourbeau J, Dransfield MT, Gershon AS, Krishnan JA, Mularski RA, Sciurba FC, Sullivan J, Feemster LC. Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report.Ann Am Thorac Soc. 2019 Feb;16(2):161-170. doi: 10.1513/AnnalsATS.201811-755WS.

January 2019

Milner SC, Bourbeau J, Ahmed S, Janaudis-Ferreira T. Improving acceptance and uptake of pulmonary rehabilitation after acute exacerbation of COPD: Acceptability, feasibility, and safety of a PR “taster” session delivered before hospital discharge. Chron Respir Dis. 2019 Jan-Dec;16:1479973119872517. doi: 10.1177/1479973119872517. PMID: 31505942 [PubMed – in process]

Shourian M, Qureshi STResistance and Tolerance to Cryptococcal Infection: An Intricate Balance That Controls the Development of Disease. Front Immunol. 2019 Jan 29;10:66. doi: 10.3389/fimmu.2019.00066. eCollection 2019. Review.

Shieh B, Beaudoin S, Gonzalez AVThe Pathway to Definitive Palliation of Malignant Pleural Effusions. Ann Am Thorac Soc. 2019 Jan 29. doi: 10.1513/AnnalsATS.201811-770RL. [Epub ahead of print] No abstract available. 

Mésidor M, Benedetti A, El-Zein M, Menzies D, Parent MÉ, Rousseau MC.  Asthma phenotypes based on health services use for allergic diseases in a province-wide birth cohort. Ann Allergy Asthma Immunol. 2019 Jan;122(1):50-57.e2. doi: 10.1016/j.anai.2018.09.453. Epub 2018 Sep 14.

Campbell JR, Menzies DWhat is Next for the Standard Short-Course Regimen for Treatment of Multidrug-Resistant Tuberculosis.Am J Trop Med Hyg. 2019 Jan 14. doi: 10.4269/ajtmh.18-0985. [Epub ahead of print]

Baril AA, Osorio RS, Carrier J, Kaminska M, Gosselin N. Reply to: Obstructive Sleep Apnea and Cognitive Decline in Older Adults.  Am J Respir Crit Care Med. 2019 Jan 16. doi: 10.1164/rccm.201812-2280LE. [Epub ahead of print] No abstract available.

Evans D, Shure D, Clark L, Criner GJ, Dres M, de Abreu MG, Laghi F, McDonagh D, Petrof B, Nelson T, Similowski T. Temporary transvenous diaphragm pacing vs. standard of care for weaning from mechanical ventilation: study protocol for a randomized trial. Trials. 2019 Jan 17;20(1):60. doi: 10.1186/s13063-018-3171-9.

Eddy RL, Westcott A, Maksym GN, Parraga G, Dandurand RJOscillometry and pulmonary magnetic resonance imaging in asthma and COPD. Physiol Rep. 2019 Jan;7(1):e13955. doi: 10.14814/phy2.13955.

Leung M, McCusker C, Ben-Shoshan M. Anaphylaxis to patent blue dye in a 17-year-old boy. BMJ Case Rep. 2019 Jan 22;12(1). pii: e226191. doi: 10.1136/bcr-2018-226191.

Costiniuk CT, Nitulescu R, Saneei Z, Wasef N, Salahuddin S, Wasef D, Young J, de Castro C, Routy JP, Lebouché B, Cox J, Smith BM, Ambroise S, Pexos C, Patel M, Szabo J, Haraoui LP, de Pokomandy A, Tsoukas C, Falutz J, LeBlanc R, Giannakis A, Frenette C, Jenabian MA, Bourbeau J, Klein MB.  Prevalence and predictors of airflow obstruction in an HIV tertiary care clinic in Montreal, Canada: a cross-sectional study.  HIV Med. 2019 Jan 8. doi: 10.1111/hiv.12699. [Epub ahead of print] 

Mancini M, Caignard G, Charbonneau B, Dumaine A, Wu N, Leiva-Torres GA, Gerondakis S, Pearson A, Qureshi ST, Sladek R, Vidal SM. Rel-Dependent Immune and Central Nervous System Mechanisms Control Viral Replication and Inflammation during Mouse Herpes Simplex Encephalitis.J Immunol. 2019 Jan 25. pii: ji1800063. doi: 10.4049/jimmunol.1800063. [Epub ahead of print]

Paine NJ, Bacon SL, Bourbeau J, Tan WC, Lavoie KL; CanCOLD Study Investigators, Aaron SD, Chapman KR, FitzGerald JM, Hernandez P, Marciniuk DD, Maltais F, O’Donnell DE, Sin D, Walker BL; Canadian Respiratory Research Network and teh CanCOLD Collaborative Research Group. Psychological distress is related to poor health behaviours in COPD and non-COPD patients: Evidence from the CanCOLD study. Respir Med. 2019 Jan;146:1-9. doi: 10.1016/j.rmed.2018.11.006. Epub 2018 Nov 15.

Romanowski K, Campbell JR, Oxlade O, Fregonese F, Menzies D, Johnston JC. The impact of improved detection and treatment of isoniazid resistant tuberculosis on prevalence of multi-drug resistant tuberculosis: A modelling study. PLoS One. 2019 Jan 24;14(1):e0211355. doi: 10.1371/journal.pone.0211355. eCollection 2019.

Leduc-Gaudet JP, Reynaud O, Hussain SN, Gouspillou G. Parkin overexpression protects from aging-related loss of muscle mass and strength.  J Physiol. 2019 Jan 7. doi: 10.1113/JP277157. [Epub ahead of print] PMID: 30614532 [PubMed – as supplied by publisher]

December 2018

Divangahi M, Khan N, Kaufmann E.  Beyond Killing Mycobacterium tuberculosis: Disease Tolerance.  Front Immunol. 2018 Dec 19;9:2976. doi: 10.3389/fimmu.2018.02976. eCollection 2018. Review.

Variane GF, Cunha LM, Pinto P, Brandao P, Mascaretti RS, Magalhães M, Sant’Anna GM. Therapeutic Hypothermia in Brazil: A MultiProfessional National Survey.  Am J Perinatol. 2018 Dec 15. doi: 10.1055/s-0038-1676052. [Epub ahead of print]

Desjardins M, Arjunaraja S, Stinson JR, Dorjbal B, Sundaresan J, Niemela J, Raffeld M, Matthews HF, Wang A, Angelus P, Su HC, Mazer BD, Snow AL.  A Unique Heterozygous CARD11 Mutation Combines Pathogenic Features of Both Gain- and Loss-of-Function Patients in a Four-Generation Family.  Front Immunol. 2018 Dec 12;9:2944. doi: 10.3389/fimmu.2018.02944. eCollection 2018.  

Front Endocrinol (Lausanne). 2018 Nov 16;9:659. doi: 10.3389/fendo.2018.00659. eCollection 2018. Depletion of BAFF cytokine exacerbates infection in Pseudomonas aeruginosa infected mice. J Cyst Fibros. 2018 Dec 7. pii: S1569-1993(18)30864-6. doi: 10.1016/j.jcf.2018.11.015. [Epub ahead of print]

Van Hulst  A, Paradis G, Benedetti A, Barnett TA, Henderson M.  Pathways Linking Birth Weight and Insulin Sensitivity in Early Adolescence: A Double Mediation Analysis.  J Clin Endocrinol  2018 Dec 1;103(12):4524-4532. doi: 10.1210/jc.2018-00525.

November 2018

Roussel L, Landekic M, Golizeh M, Gavino C, Zhong MC, Chen J, Faubert D, Blanchet-Cohen A, Dansereau L, Parent MA, Marin S, Luo J, Le C, Ford BR, Langelier M, King IL, Divangahi M, Foulkes WD, Veillette A, Vinh DC. Loss of human ICOSL results in combined immunodeficiency. J Exp Med. 2018 Nov 29. pii: jem.20180668. doi: 10.1084/jem.20180668. [Epub ahead of print]

Yazdchi SB, Witalis M, Meli AP, Leung J, Li X, Panneton V, Chang J, Li J, Nutt SL, Johnson RL, Lim DS, Gu H, King IL, Suh WK. Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity.  J Immunol. 2018 Nov 26. pii: ji1701407. doi: 10.4049/jimmunol.1701407. [Epub ahead of print]

Juban G, Saclier M, Yacoub-Youssef H, Kernou A, Arnold L, Boisson C, Ben Larbi S, Magnan M, Cuvellier S, Théret M, Petrof BJ, Desguerre I, Gondin J, Mounier R, Chazaud B. AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.  Cell Rep. 2018 Nov 20;25(8):2163-2176.e6. doi: 10.1016/j.celrep.2018.10.077.

McGrath S, Zhao X, Qin ZZ, Steele R, Benedetti A. One-sample aggregate data meta-analysis of medians. Stat Med. 2018 Nov 20. doi: 10.1002/sim.8013. [Epub ahead of print]

Pamidi S, Meltzer SJ, Garfield N, Lavigne L, Olha A, Khalyfa A, Benedetti A, Tremblay G, Gagnon R, Rey E, Dasgupta K, Kimoff RJ.  A Pilot Randomized-Controlled Trial on the Effect of CPAP Treatment on Glycemic Control in Gestational Diabetes: Study Design and Methods.  Front Endocrinol (Lausanne). 2018 Nov 16;9:659. doi: 10.3389/fendo.2018.00659. eCollection 2018.

Nsengiyumva NP, Mappin-Kasirer B, Oxlade O, Bastos M, Trajman A, Falzon D, Schwartzman K.  Evaluating the potential costs and impact of digital health technologies for tuberculosis treatment support.  Eur Respir J. 2018 Nov 1;52(5). pii: 1801363. doi: 10.1183/13993003.01363-2018. Print 2018 Nov.

Divangahi M. Are tolerance and training required to end TB?  Nat Rev Immunol. 2018 Nov;18(11):661-663. doi: 10.1038/s41577-018-0070-y.

Lee S, Shan J, Aldossary H, Gaudreault V, Bazett M, Fixman EDSTAT6 inhibitory peptide reduces dendritic cell migration to the lymph nodes to control Th2 adaptive immunity in the mouse lung. Eur J Immunol. 2018 Nov 14. doi: 10.1002/eji.201847534. [Epub ahead of print]

Martin P, Tamblyn R, Benedetti A, Ahmed S, Tannenbaum C. Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial. JAMA. 2018 Nov 13;320(18):1889-1898. doi: 10.1001/jama.2018.16131.

Romanowski K, Balshaw RF, Benedetti A, Campbell JR, Menzies D, Ahmad Khan F, Johnston JC. Predicting tuberculosis relapse in patients treated with the standard 6-month regimen: an individual patient data meta-analysis. Thorax. 2018 Nov 12. pii: thoraxjnl-2017-211120. doi: 10.1136/thoraxjnl-2017-211120. [Epub ahead of print]

Sanchez V, Golyardi F, Mayaki D, Echavarria R, Harel S, Xia J, Hussain SNANegative regulation of angiogenesis by novel micro RNAs. Pharmacol Res. 2018 Nov 8. pii: S1043-6618(18)30779-5. doi: 10.1016/j.phrs.2018.11.010. [Epub ahead of print]

Shalish W, Kanbar L, Kovacs L, Chawla S, Keszler M, Rao S, Panaitescu B, Laliberte A, Precup D, Brown K, Kearney RE, Sant’Anna GMThe Impact of Time Interval between Extubation and Reintubation on Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants. J Pediatr. 2018 Nov 5. pii: S0022-3476(18)31392-1. doi: 10.1016/j.jpeds.2018.09.062. [Epub ahead of print]

Van Hulst A, Paradis G, Harnois-Leblanc S, Benedetti A, Drapeau V, Henderson M.  Lowering Saturated Fat and Increasing Vegetable and Fruit Intake May Increase Insulin Sensitivity 2 Years Later in Children with a Family History of Obesity.  J Nutr. 2018 Nov 1;148(11):1838-1844. doi: 10.1093/jn/nxy189.

October 2018

Siddique AA, Schnitzer ME, Bahamyirou A, Wang G, Holtz TH, Migliori GB, Sotgiu G, Gandhi NR, Vargas MH, Menzies D, Benedetti A.  Causal inference with multiple concurrent medications: A comparison of methods and an application in multidrug-resistant tuberculosis.  Med Res. 2018 Oct 31:962280218808817. doi: 10.1177/0962280218808817. [Epub ahead of print]

Matusovsky OS, Kachmar L, Ijpma G, Panariti A, Benedetti A, Martin JG, Lauzon AM.  Contractile Properties of Intrapulmonary Airway Smooth Muscle in Cystic Fibrosis.  Am J Respir Cell Mol Biol. 2018 Oct 25.  doi: 10.1165/rcmb.2018-0005OC. [Epub ahead of print]

Smith BM, Jensen D, Brosseau M, Benedetti A, Coxson HO, Bourbeau JImpact of pulmonary emphysema on exercise capacity and its physiological determinants in chronic obstructive pulmonary disease.  Sci Rep. 2018 Oct 24;8(1):15745. doi: 10.1038/s41598-018-34014-5.

Roberge JB, Van Hulst A, Barnett TA, Drapeau V, Benedetti A, Tremblay A, Henderson M. Lifestyle Habits, Dietary Factors, and the Metabolically Unhealthy Obese Phenotype in Youth. J Pediatr. 2018 Oct 23.  doi: 10.1016/j.jpeds.2018.08.063. [Epub ahead of print]

Costiniuk CT, Salahuddin S, Farnos O, Olivenstein R, Pagliuzza A, Orlova M, Schurr E, De Castro C, Bourbeau J, Routy JP, Ancuta P, Chomont N, Jenabian MA.  HIV persistence in mucosal CD4+ T cells within the lungs of adults receiving long-term suppressive antiretroviral therapy.  AIDS. 2018 Oct 23;32(16):2279-2289. doi: 10.1097/QAD.0000000000001962.

Faure E, Kwong K, Nguyen DPseudomonas aeruginosa in Chronic Lung Infections: How to Adapt Within the Host? Front Immunol. 2018 Oct 22;9:2416. doi: 10.3389/fimmu.2018.02416. eCollection 2018. Review.

Juge PA, Lee JS, Ebstein E, Furukawa H, Dobrinskikh E, Gazal S, Kannengiesser C, Ottaviani S, Oka S, Tohma S, Tsuchiya N, Rojas-Serrano J, González-Pérez MI, Mejía M, Buendía-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou K, van Moorsel CHM, van der Vis J, de Man YA, Grutters JC, Wang Y, Borie R, Wemeau-Stervinou L, Wallaert B, Flipo RM, Nunes H, Valeyre D, Saidenberg-Kermanac’h N, Boissier MC, Marchand-Adam S, Frazier A, Richette P, Allanore Y, Sibilia J, Dromer C, Richez C, Schaeverbeke T, Lioté H, Thabut G, Nathan N, Amselem S, Soubrier M, Cottin V, Clément A, Deane K, Walts AD, Fingerlin T, Fischer A, Ryu JH, Matteson EL, Niewold TB, Assayag D, Gross A, Wolters P, Schwarz MI, Holers M, Solomon JJ, Doyle T, Rosas IO, Blauwendraat C, Nalls MA, Debray MP, Boileau C, Crestani B, Schwartz DA, Dieudé P. MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease. N Engl J Med. 2018 Oct 20.   doi: 10.1056/NEJMoa1801562. [Epub ahead of print]

Paulin LM, Smith BM, Koch A, Han M, Hoffman EA, Martinez C, Ejike C, Blanc PD, Rous J, Barr RG, Peters SP, Paine R 3rd, Pirozzi C, Cooper CB, Dransfield MT, Comellas AP, Kanner RE, Drummond MB, Putcha N, Hansel NN. Occupational Exposures Influence CT Imaging Characteristics in the SPIROMICS Cohort.  Ann Am Thorac Soc. 2018 Oct 19.  doi: 10.1513/AnnalsATS.201802-150OC. [Epub ahead of print]

Barss L, Menzies D.  Using a quality improvement approach to improve care for latent tuberculosis infection.  Expert Rev Anti Infect Ther. 2018 Oct;16(10):737-747. doi: 10.1080/14787210.2018.1521269.

Troosters T, Maltais F, Leidy N, Lavoie KL, Sedeno M, Janssens W, Garcia-Aymerich J, Erzen D, De Sousa D, Korducki L, Hamilton A, Bourbeau J.  Effect of Bronchodilation, Exercise Training, and Behavior Modification on Symptoms and Physical Activity in Chronic Obstructive Pulmonary Disease.  Am J Respir Crit Care Med 2018 Oct 15;198(8):1021-1032. doi: 10.1164/rccm.201706-1288OC.

Abdallah SJ, Smith BM, Ware MA, Moore M, Li PZ, Bourbeau J, Jensen D.  Effect of Vaporized Cannabis on Exertional Breathlessness and Exercise Endurance in Advanced Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial.  Ann Am Thorac Soc. 2018 Oct;15(10):1146-1158. doi: 10.1513/AnnalsATS.201803-198OC.

Coats V, Després JP, Alméras N, Martin M, Sin DD, Rabasa-Lhoret R, Larose É, Tan WC, Bourbeau J, Maltais F; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network. Ectopic adiposity and cardiometabolic health in COPD.  Int J Chron Obstruct Pulmon Dis. 2018 Oct 15;13:3331-3340. doi: 10.2147/COPD.S168963. eCollection 2018.

Hebestreit H, Hulzebos EH, Schneiderman JE, Karila C, Boas SR, Kriemler S, Dwyer T, Sahlberg M, Urquhart DS, Lands LC, Ratjen F, Takken T, Varanistkaya L, Rücker V, Hebestreit A, Usemann J, Radtke T. Cardiopulmonary exercise testing provides additional prognostic information in cystic fibrosis.  Am J Respir Crit Care Med. 2018 Oct 15. doi: 10.1164/rccm.201806-1110OC. [Epub ahead of print]

Law S, Daftary A, O’Donnell M, Padayatchi N, Calzavara L, Menzies DInterventions to improve Fretention-in-care and treatment adherence among patients with drug-resistant tuberculosis: a systematic review. Eur Respir J. 2018 Oct 11. pii: 1801030. doi: 10.1183/13993003.01030-2018. [Epub ahead of print]

Magder S. The meaning of blood pressure.Crit Care. 2018 Oct 11;22(1):257. Review. doi: 10.1186/s13054-018-2171-1.  doi: 10.1186/s13054-018-2171-1.

Veit G, Xu H, Dreano E, Avramescu RG, Bagdany M, Beitel LK, Roldan A, Hancock MA, Lay C, Li W, Morin K, Gao S, Mak PA, Ainscow E, Orth AP, McNamara P, Edelman A, Frenkiel S, Matouk E, Sermet-Gaudelus I, Barnes WG, Lukacs GL. Structure-guided combination therapy to potently improve the function of mutant CFTRs. Nat Med. 2018 Oct 8. [Epub ahead of print]

Henderson M, Van Hulst A, Von Oettingenn JE, Benedetti A, Paradis G. Normal weight metabolically unhealthy phenotype in youth: do definitions matter? Pediatr Diabetes. 2018 Oct 8. doi: 10.1111/pedi.12785. [Epub ahead of print]

Bond S, Léguillette R, Richard EA, Couetil L, Lavoie JP, Martin JG, Pirie RS.  Equine asthma: Integrative biologic relevance of a recently proposed nomenclature. J Vet Intern Med. 2018 Oct 7.  doi: 10.1111/jvim.15302. [Epub ahead of print]

Lima VP, Velloso M, Almeida FD, Carmona B, Ribeiro-Samora GA, Janaudis-Ferreira T.  Test-retest reliability of the unsupported upper-limb exercise test (UULEX) and 6-min peg board ring test (6PBRT) in healthy adult individuals.  Physiother Theory Pract. 2018 Oct;34(10):806-812

Lemay AM, Haston CKA Chromosome 6, not Natural Killer Cell, Contribution to Radiation- and Bleomycin-Induced Lung Disease in Mice. Radiat Res. 2018 Oct 2. doi: 10.1667/RR15144.1. [Epub ahead of print]

Schiff GD, Martin SA, Eidelman DH, Volk LA, Ruan E, Cassel C, Galanter W, Johnson M, Jutel A, Kroenke K, Lambert BL, Lexchin J, Myers S, Miller A, Mushlin S, Sanders L, Sheikh A. Ten Principles for More Conservative, Care-Full Diagnosis. Ann Intern Med. 2018 Oct 2. [Epub ahead of print] No abstract available.

September 2018

Jensen D, Schaeffer MR, Guenette JA.  Pathophysiological mechanisms of exertional breathlessness in chronic obstructive pulmonary disease and interstitial lung disease.  Curr Opin Support Palliat Care. 2018 Sep.12(3):237-245. doi: 10.1097/SPC.0000000000000377.

Ware MA, Jensen D, Barrette A, Vernec A, Derman W.  Cannabis and the Health and Performance of the Elite Athlete.  Clin J Sport Med. 2018 Sep;28(5):480-484. doi: 10.1097/JSM.0000000000000650.

Martins D, McKay G, Sampathkumar G, Khakimova M, English AM, Nguyen DSuperoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosaProc Natl Acad Sci USA 2018 Sep 25;115(39):9797-9802

King IL, Li Y. Host-Parasite Interactions Promote Disease Tolerance to Intestinal Helminth Infection. Front Immunol. 2018 Sep 20;9:2128. Review.  doi: 10.1186/s13054-018-2171-1.

Ishihara M, Harel D, Levis B, Levis AW, Riehm KE, Saadat N, Azar M, Rice DB, Sanchez TA, Chiovitti MJ, Cuijpers P, Gilbody S, Ioannidis JPA, Kloda LA, McMillan D, Patten SB, Shrier I, Arroll B, Bombardier CH, Butterworth P, Carter G, Clover K, Conwell Y, Goodyear-Smith F, Greeno CG, Hambridge J, Harrison PA, Hudson M, Jetté N, Kiely KM, McGuire A, Pence BW, Rooney AG, Sidebottom A, Simning A, Turner A White J, Whooley MA, Winkley K, Benedetti A, Thombs BD.  Shortening self-report mental health symptom measures through optimal test assembly methods: Development and validation of the Patient Health Questionnaire-Depression-4. Depress Anxiety. 2018 Sep 20 doi: 10.1002/da.22841. [Epub ahead of print]

Chen PG, Bassiouni A, Taylor CB, Psaltis AJ, Alrasheed A, Wrobel B, Tewfik MA, McMains KC.  Teaching Residents Frontal Sinus Anatomy Using a Novel 3-Dimensional Conceptualization Planning Software-Based Module.  Am J Rhinol Allergy. 2018 Sep 19:1945892418801264

Chalak LF, Nguyen KA, Prempunpong C, Heyne R, Thayyil S, Shankaran S, Laptook AR, Rollins N, Pappas A, Koclas L, Shah B, Montaldo P, Techasaensiri B, Sánchez PJ, Sant’Anna GProspective research in infants with mild encephalopathy identified in the first six hours of life: neurodevelopmental outcomes at 18-22 months. Pediatr Res. 2018 Sep 13. doi: 10.1038/s41390-018-0174-x. [Epub ahead of print]

McCusker C, Upton J, Warrington R. Primary immunodeficiency. Allergy Asthma Clin Immunol. 2018 Sep 12. ;14(Suppl 2):61. doi: 10.1186/s13223-018-0290-5. eCollection 2018.

Rose L, McKim D, Leasa D, Nonoyama M, Tandon A, Kaminska M, O’Connell C, Loewen A, Connolly B, Murphy P, Hart N, Road J.  Monitoring Cough Effectiveness and Use of Airway Clearance Strategies: A Canadian and UK Survey. Respir Care. 2018 Sep 11. pii: respcare.06321. doi: 10.4187/respcare.06321. [Epub ahead of print]

Martins D, McKay G, Sampathkumar G, Khakimova M, English AM, Nguyen DSuperoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2018 Sep 10. pii: 201804525. doi: 10.1073/pnas.1804525115. [Epub ahead of print] PMID: 30201715 [PubMed – as supplied by publisher]Free Article

Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017, Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D’Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fréchet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Laborín R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ11, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O’Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K77, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.  Lancet. 2018 Sep 8;392(10150):821-834. doi: 10.1016/S0140-6736(18)31644-1.

Schwartzman K. You pay for what you get: the true cost of tuberculosis.  Int J Tuberc Lung Dis. 2018 Sep 1;22(9):969. doi: 10.5588/ijtld.18.0416.

Bergeron ME, Stefanov A, Haston CK., Fine mapping of the major bleomycin-induced pulmonary fibrosis susceptibility locus in mice., Mamm Genome. 2018 Oct;29(9-10):670-679. doi: 10.1007/s00335-018-9774-3. Epub 2018 Sep 1.  

August 2018

Kaminska M, Bourbeau J, Kimoff RJ. Bariatric Surgery and the Risk of Acute Exacerbation of COPD: Possible Role of OSA?  Chest. 2018 Aug;154(2):456-457. doi: 10.1016/j.chest.2018.04.012.

Thombs BD, Levis B, Rice DB, Wu Y, Benedetti A. Reducing Waste and Increasing the Usability of Psychiatry Research: The Family of EQUATOR Reporting Guidelines and One of Its Newest Members: The PRISMA-DTA Statement. Can J Psychiatry. 2018 Aug 63(8):509-512. doi: 10.1177/0706743718773705. Epub 2018 Apr 25.

Petrof BJ., Diaphragm Weakness in the Critically Ill: Basic Mechanisms Reveal Therapeutic Opportunities.Chest. 2018 Aug 23.  pii: S0012-3692(18)32242-6. doi: 10.1016/j.chest.2018.08.1028. [Epub ahead of print] 

Kesimer M, Smith BM, Ceppe A, Ford AA, Anderson WH, Barr RG, O’Neal W, Boucher RC., Mucin Concentrations and Peripheral Airways Obstruction in COPD.Am J Respir Crit Care Med. 2018 Aug 21. doi: 10.1164/rccm.201806-1016LE. [Epub ahead of print] No abstract available., 

Gosselin N, Baril AA, Osorio RS, Kaminska M, Carrier J.  Obstructive Sleep Apnea and the Risk of Cognitive Decline in Older Adults.  Am J Respir Crit Care Med. 2018 Aug 16. doi: 10.1164/rccm.201801-0204PP. [Epub ahead of print]

Lachapelle P, Cascon J, Pamidi S, Kimoff RJ., Accuracy of portable devices in sleep apnea using oximetry-derived heart rate increases as a surrogate arousal marker., Sleep Breath. 2018 Aug 15. 

Petrof BJ, Sassoon CS. Diaphragm Remodeling during Application of Positive End-Expiratory Pressure. A Case of Normal Physiologic Adaptation Gone Awry.  Am J Respir Crit Care Med. 2018 Aug 15;198(4):416-418. doi: 10.1164/rccm.201803-0518ED.

Martin JG. Airway smooth muscle may drive mucus hypersecretion in asthma. Eur Respir J. 2018 Aug 9;52(2). pii: 1801166. doi: 10.1183/13993003.01166-2018. Print 2018 Aug.

Ijpma G, Qiao LC, Kachmar L, Panariti A, Benedetti A, Lavoie JP, Lauzon AMMaintenance of Contractile function of isolated airway smooth muscle after cryopreservation.  Am J Physiol Lung Cell Mol Physiol. 2018 Aug 9

Vincent AE, Rosa HS, Pabis K, Lawless C, Chen C, Grünewald A, Rygiel KA, Rocha MC, Reeve AK, Falkous G, Perissi V, White K, Davey T, Petrof BJ, Sayer AA, Cooper C, Deehan D, Taylor RW, Turnbull DM, Picard M. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann Neurol. 2018 Aug;8

Johnson KM, Tan WC, Bourbeau J, Sin DD, Sadatsafavi M.  Canadian Cohort of Obstructive Lung Disease (CanCOLD) study and the Canadian Respiratory Research Network. The diagnostic performance of patient symptoms in screening for COPD. Respir Res. 2018 Aug 3;19(1):147

Diallo T, Adjobimey M, Ruslami R, Trajman A, Sow O, Obeng Baah J, Marks GB, Long R, Elwood K, Zielinski D, Gninafon M, Wulandari DA, Apriani L, Valiquette C, Fregonese F, Hornby K, Li PZ, Hill PC, Schwartzman K, Benedetti A, Menzies D. Safety and Side Effects of Rifampin versus Isoniazid in Children. N Engl J Med. 2018 Aug 2

Guinhouya BC, Bisson M, Dubois L, Sériès F, Kimoff JR, Fraser WD, Marc I. Body Weight Status and Sleep Disturbances During Pregnancy: Does Adherence to Gestational Weight Gain Guidelines Matter? J Womens Health (Larchmt). 2018 Aug 1. 

Menzies D, Adjobimey M, Ruslami R, Trajman A, Sow O, Kim H, Obeng Baah J, Marks GB, Long R, Hoeppner V, Elwood K, Al-Jahdali H, Gninafon M, Apriani L, Koesoemadinata RC, Kritski A, Rolla V, Bah B, Camara A, Boakye I, Cook VJ, Goldberg H, Valiquette C, Hornby K, Dion MJ, Li PZ, Hill PC, Schwartzman K, Benedetti A.  Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults. N Engl J Med. 2018 Aug 2.

Rousseau MC, El-Zein M, Conus F, Parent ME, Benedetti A. Cohort Profile: The Québec Birth Cohort on Immunity and Health (QBCIH). Int J Epidemiol. 2018 Aug 1;47(4):1040-1041h. doi: 10.1093/ije/dyy011.

Carlile GW, Yang Q, Matthes E, Liao J, Radinovic S, Miyamoto C, Robert R, Hanrahan JW, Thomas DY.  A novel triple combination of pharmacological chaperones improves F508del-CFTR correction.  Sci Rep. 2018 Jul 30;8(1):11404. doi: 10.1038/s41598-018-29276-y.

July 2018

Kanbar LJ, Onu CC, Shalish W, Brown KA, SantrAnna GM, Precup D, Kearney RE. Undersampling and Bagging of Decision Trees in the Analysis of Cardiorespiratory Behavior for the Prediction of Extubation Readiness in Extremely Preterm Infants. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4940-4944. doi: 10.1109/EMBC.2018.8513194.

Matthes E, Hanrahan JW, Cantin AM.  F508del-CFTR is not corrected by thymosin α1.  Nat Med. 2018 Jul;24(7):890-891. doi: 10.1038/s41591-018-0079-6.

Hassan GS, Jacques D, D’Orléans-Juste P, Magder S, Bkaily G. Physical contact between human vascular endothelial and smooth muscle cells modulates cytosolic and nuclear calcium homeostasis. Can J Physiol Pharmacol. 2018 Jul.

Allard B, Panariti A, Martin JG., Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection.Front Immunol. 2018 Jul 31;9:1777. doi: 10.3389/fimmu.2018.01777. eCollection 2018. Review., PMID: 30108592 [PubMed – in process] Free PMC Article

Gentile ME, King IL., Blood and guts: The intestinal vasculature during health and helminth infection. PLoS Pathog. 2018 Jul 19;14(7):e1007045. doi: 10.1371/journal.ppat.1007045. eCollection 2018 Jul. No abstract available., PMID: 30024980 [PubMed – in process]

Abdallah SJ, Smith BM, Ware MA, Moore M, Li PZ, Bourbeau J, Jensen D. Effect of Vaporized Cannabis on Exertional Breathlessness and Exercise Endurance in Advanced COPD: A Randomized Controlled Trial. Ann Am Thorac Soc. 2018 Jul 27. doi: 10.1513/AnnalsATS.201803-198OC. [Epub ahead of print]

Vincent AE, Rosa HS, Pabis K, Lawless C, Chen C, Grünewald A, Rygiel KA, Rocha MC, Reeve AK, Falkous G, Perissi V, White K, Davey T, Petrof BJ, Sayer AA, Cooper C, Deehan D, Taylor RW, Turnbull DM, Picard M. Sub-cellular origin of mtDNA deletions in human skeletal muscle.  Ann Neurol. 2018 Jul 16. doi: 10.1002/ana.25288. [Epub ahead of print]  

Blackstock FC, Lareau SC, Nici L, ZuWallack R, Bourbeau J, Buckley M, Durning SJ, Effing TW, Egbert E, Goldstein RS, Kelly W, Lee A, Meek PM, Singh S; American Thoracic Society, Thoracic Society of Australia and New Zealand, Canadian Thoracic Society, and British Thoracic Society.  Chronic Obstructive Pulmonary Disease Education in Pulmonary Rehabilitation. An Official American Thoracic Society/Thoracic Society of Australia and New Zealand/Canadian Thoracic Society/British Thoracic Society Workshop Report.  Ann Am Thorac Soc. 2018 Jul;15(7):769-784. doi: 10.1513/AnnalsATS.201804-253WS.

Miller AC, Livchits V, Ahmad Khan F, Atwood S, Kornienko S, Kononenko Y, Vasilyeva I, Keshavjee S.  Turning Off the Tap: Using the FAST Approach to Stop the Spread of Drug-Resistant Tuberculosis in the Russian FederationJ Infect Dis 2018 Jul 13;218(4):654-658

Cottrell J, Yip J, Chan Y, Chin CJ, Damji A, de Almeida JR, Desrosiers M, Janjua A, Kilty S, Lee JM, Macdonald KI, Meen EK, Rudmik L Sommer DD, Sowerby L, Tewfik MA, Vescan AD, Witterick IJ, Wright E, Monteiro E.  Quality indicators for the diagnosis and management of chronic rhinosinusitis.  Int Forum Allergy Rhinol. 2018 Jul 12.

Harausz EP, Garcia-Prats A, Law S, Schaaf HS, Kredo T, Seddon JA, Menzies D, Turkova A, Achar J, Amanullah F, Barry P, Becerra M, Chan ED, Chan PC, Ioana Chiotan D, Crossa A, Drobac PC, Fairlie L, Falzon D, Flood J, Gegia M, Hicks RM, Isaakidis P, Kadri SM, Kampmann B, Madhi SA, Marais E, Mariandyshev A, Méndez-Echevarría A, Moore BK, Nargiza P, Ozere I, Padayatchi N, Ur-Rehman S, Rybak N, Santiago-Garcia B, Shah NS, Sharma S, Shim TS, Skrahina A, Soriano-Arandes A, van den Boom M, van der Werf MJ, van der Werf TS, Williams B, Yablokova E, Yim JJ, Furin J, Hesseling AC, Collaborative Group for Meta-Analysis of Paediatric Individual Patient Data in MDR-TB.  Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis.  PLoS Med. 2018 Jul 11;15(7):e1002591

Diab N, Gershon AS, Sin DD, Tan WC, Bourbeau J, Boulet LP, Aaron SD. Under-diagnosis and Over-diagnosis of Chronic Obstructive Pulmonary Disease.  Am J Respir Crit Care Med. 2018 Jul 6.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T7, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.  Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial. Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.

Chourey S, Ye Q, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS.  Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE).  J Med Chem. 2018 Jul 4. doi: 0.1021/acs.jmedchem.8b00154. [Epub ahead of print] 

Chennakrishnaiah S, Meehan B, D’Asti E, Montermini L, Lee TH, Karatzas N, Buchanan M, Tawil N, Choi D, Divangahi M, Basik M, Rak J.  Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor-derived extracellular vesicles. J Thromb Haemost2018 Jul 3. doi: 10.1111/jth.14222. 

June 2018

Baglole CJ, Liang F, Traboulsi H, Rico de Souza A, Giordano C, Tauer JT, Rauch F, Petrof BJ.  Pulmonary and diaphragmatic pathology in collagen type I α1 mutant mice with osteogenesis imperfecta. Pediatr Res. 2018 Jun

Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti MJ, Sanchez TA, Cuijpers P, Gilbody S, Ioannidis JPA, Kloda LA, McMillan D, Patten SB, Shrier I, Steele RJ, Ziegelstein RC, Akena DH, Arroll B, Ayalon L, Baradaran HR, Baron M, Beraldi A, Bombardier CH, Butterworth P, Carter G, Chagas MH, Chan JCN, Cholera R, Chowdhary N, Clover K, Conwell Y, de Man-van Ginkel JM, Delgadillo J, Fann JR, Fischer FH, Fischler B, Fung D, Gelaye B, Goodyear-Smith F, Greeno CG, Hall BJ, Hambridge J, Harrison PA, Hegerl U, Hides L, Hobfoll SE, Hudson M, Hyphantis T, Inagaki M, Ismail K, Jetté N, Khamseh ME. Kiely KM, Lamers F, Liu SI, Lotrakul M, Loureiro SR, Löwe B, Marsh L, McGuire A, Mohd Sidik S, Munhoz TN, Muramatsu K, Osório FL, Patel V5 Pence BW, Persoons P, Picardi A, Rooney AG, Santos IS, Shaaban J, Sidebottom A, Simning A, Stafford L, Sung S, Tan PLL, Turner A, van der Feltz-Cornelis CM, van Weert HC, Vöhringer PA, White J, Whooley MA, Winkley K, Yamada M, Zhang Y, Thombs BD.  Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. Br J Psychiatry. 2018 Jun

Guak H, Al Habyan S, Ma EH, Aldossary H, Al-Masri M, Won SY, Ying T, Fixman ED, Jones RG, McCaffrey LM, Krawczyk CM. Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration. Nat Commun. 2018 Jun 25;9(1):2463. doi: 10.1038/s41467-018-04804-6.

Valera FCP, Ruffin M, Adam D, Maillé É, Ibrahim B, Berube J, Rousseau S, Brochiero E, Desrosiers MY.  Staphylococcus aureus impairs sinonasal epithelial repair: Effects in patients with chronic rhinosinusitis with nasal polyps and control subjects.  J Allergy Clin Immunol. 2018 Jun 20

Gagné M, Moisan J, Lauzier S, Hamel C, Côté P, Bourbeau J, Boulet LP. Comparative impact of two continuing education activities targeted at COPD educators on educational outcomes: protocol for a non-randomized controlled study using mixed methods. BMC Health Serv Res. 2018 Jun 18;18(1):460. doi: 10.1186/s12913-018-3284-6.

Gershon AS, Thiruchelvam D, Chapman KR, Aaron SD, Stanbrook MB, Bourbeau J, Tan W, To T; Canadian Respiratory Research Network.  Health Services Burden of Undiagnosed and Overdiagnosed COPD.  Chest. 2018 Jun15.

Oelsner EC, Smith BM, Hoffman EA, Kalhan R, Donohue KM, Kaufman JD, Nguyen JN, Manichaikul AW, Rotter JI, Michos ED, Jacobs DR Jr, Burke GL, Folsom AR, Schwartz JE, Watson K, Barr RG. Prognostic Significance of Large Airway Dimensions on Computed Tomography in the General Population. The Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study. Ann Am Thorac Soc. 2018 Jun;15(6):718-727.

Restori KH, Srinivasa BT, Ward BJ, Fixman EDNeonatal Immunity, Respiratory Virus Infections, and the Development of Asthma. Front Immunol. 2018 Jun 4;9:1249. doi: 10.3389/fimmu.2018.01249. eCollection 2018. Review.

Valera FC, Ruffin M, Adam D, Maillé É, Ibrahim B, Berube J, Rousseau S, Brochiero E, Desrosiers MY. Staphylococcus aureus impairs sinonasal epithelial repair: effects in CRSwNP and control subjects.  J Allergy Clin Immunol. 2018 Jun 20. pii: S0091-6749(18)30894-7. doi: 10.1016/j.jaci.2018.05.035. [Epub ahead of print]

Jomphe V, Lands LC, Mailhot G. Nutritional Requirements of Lung Transplant Recipients: Challenges and Considerations. Nutrients. 2018 Jun 19;10(6). pii: E790. doi: 10.3390/nu10060790. Review.

Janaudis-Ferreira T, Carr SJ, Harrison SL, Gershon AS, Milner SC, Carr S, Fishbein D, Goldstein R.  Can Patients With COPD Assimilate Disease-Specific Information During an Acute Exacerbation?: Results of a Pilot Randomized Controlled Trial.  Chest. 2018 Sep;154(3):588-596. doi: 10.1016/j.chest.2018.05.028. Epub 2018 Jun 4.

May 2018

Naderi N, Assayag D, Mostafavi-Pour-Manshadi SM, Kaddaha Z, Joubert A, Ouellet I, Drouin I, Li PZ, Bourbeau J.  Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease. Respir Med. 2018 May;

Shalish W, Kanbar L, Keszler M, Chawla S, Kovacs L, Rao S, Panaitescu BA, Laliberte A, Precup D, Brown K, Kearney RE, Sant’Anna GM.  Patterns of reintubation in extremely preterm infants: a longitudinal cohort study. Pediatr Res. 2018 May

Lima VP, Almeida FD, Janaudis-Ferreira T, Carmona B, Ribeiro-Samora GA, Velloso M. Reference values for the six-minute pegboard and ring test in healthy adults in Brazil.  J Bras Pneumol. 2018 May-Jun,

Valdés CJ, Tewfik MARhinosinusitis and Allergies in Elderly Patients.  Clin Geriatr Med. 2018 May.

Bourbeau J, Farias R.  Making sense of telemedicine in the management of COPD. Eur Respir J. 2018 May 30

Hill K, Cavalheri V, Mathur S, Roig M, Janaudis-Ferreira T, Robles P, Dolmage TE, Goldstein R.  Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease.  Cochrane Database Syst Rev. 2018 May 29

Al-Rajhi A, Shahin J.  Non-invasive ventilation in patients with community acquired pneumonia in the emergency department: Author’s response.  Am J Emerg Med. 2018 May 26

Pang A, Lingham S, Zhao W, Leduc S, Räkel A, Sapir-Pichhadze R, Mathur S, Janaudis-Ferreira TPhysician Practice Patterns and Barriers to Counselling on Physical Activity in Solid Organ Transplant Recipients. Ann Transplant. 2018 May 22;23

Moro RN, Scott NA, Vernon A, Tepper NK, Goldberg SV, Schwartzman K, Leung CC, Schluger NW, Belknap RW, Chaisson RE, Narita M, Machado ES, Lopez M, Sanchez J, Villarino ME, Sterling TR.  Exposure to Latent Tuberculosis Treatment during Pregnancy. The PREVENT TB and the iAdhere Trials. Ann Am Thorac Soc. 2018 May;15(5):570-580. doi: 10.1513/AnnalsATS.201704-326OC.

Caron M, Hoa S, Hudson M, Schwartzman K, Steele R. Pulmonary function tests as outcomes for systemic sclerosis interstitial lung disease.  Eur Respir Rev. 2018 May 15

Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WSCorrigendum to “In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys” [Biochem. Pharmacol. 138 (2017) 107-118].   2018 Aug;154:174. doi: 10.1016/j.bcp.2018.04.025. Epub 2018 May 10.

Kishta OA, Sabourin A, Simon L, McGovern T, Raymond M, Galbas T, Majdoubi A, Ishido S, Martin JG, Thibodeau J. March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation.  J Immunol Res. 2018 May 3;2018:3823910. doi: 10.1155/2018/3823910. eCollection 2018.  in process] Free Article

Tzelepis F, Blagih J, Khan N, Gillard J, Mendonca L, Roy DG, Ma EH, Joubert P, Jones RG, Divangahi M.  Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis.  Sci Immunol. 2018 May 11;3(23). pii: eaar4135. doi: 10.1126/sciimmunol.aar4135.

Pandžić E, Abu-Arish A, Whan RM, Hanrahan JW, Wiseman PW.  Velocity landscape correlation resolves multiple flowing protein populations from fluorescence image time series.  Methods. 2018 May 1;140-141:126-139

April 2018

Panariti A, Baglole CJ, Sanchez V, Eidelman DH, Hussain S, Olivenstein R, Martin JG, Hamid Q.  Interleukin-17A and vascular remodelling in severe asthma; lack of evidence for a direct role.  Clin Exp Allergy. 2018 Apr.

Ramos J, Wakoff-Pereira MF, Cordeiro-Santos M, Albuquerque MFM, Hill PC, Menzies D, Trajman A. Knowledge and perceptions of tuberculosis transmission and prevention among physicians and nurses in three Brazilian capitals with high incidence of tuberculosis. J Bras Pneumol. 2018 Apr.

Milner SC, Boruff JT, Beaurepaire C, Ahmed S, Janaudis-Ferreira TRate of, and barriers and enablers to, pulmonary rehabilitation referral in COPD: A systematic scoping review. Respir Med. 2018 Apr.

Kaminska M, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Gros P, Kimoff RJ.  Change in Cognition and Other Non-Motor Symptoms With Obstructive Sleep Apnea Treatment in Parkinson Disease.  J Clin Sleep Med. 2018 Apr 30. pii: jc-17-00563. [Epub ahead of print] PMID: 29734988 [PubMed – as supplied by publisher]

Gouspillou G, Godin R, Piquereau J, Picard M, Mofarrahi M, Mathew J, Purves-Smith FM, Sgarioto N, Hepple RT, Burelle Y, Hussain SN.  Protective role of Parkin in skeletal muscle contractile and mitochondrial function.  J Physiol. 2018 Apr 22. doi: 10.1113/JP275604. [Epub ahead of print]. PMID: 29682760 [PubMed – as supplied by publisher]

Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza AR, Baglole CJ, Aare S, MacMillan NJ, Baril J, Rozakis P, Sonjak V, Pion C, Aubertin-Leheudre M, Morais JA, Jagoe RT, Bourbeau J, Taivassalo T, Hepple RT.  Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in COPD.  J Physiol. 2018 Apr 16. doi: 10.1113/JP275558. [Epub ahead of print]

Downey J, Pernet E, Coulombe F, Divangahi M.  Dissecting host cell death programs in the pathogenesis of influenza. Microbes Infect. 2018 Apr 18. pii: S1286-4579(18)30093-5. doi: 10.1016/j.micinf.2018.03.005. [Epub ahead of print]  PMID: 29679740 [PubMed – as supplied by publisher]

Fregonese F, Ahuja SD, Akkerman OW, Arakaki-Sanchez D, Ayakaka I, Baghaei P, Bang D, Bastos M, Benedetti A, Bonnet M, Cattamanchi A, Cegielski P, Chien JY, Cox H, Dedicoat M, Erkens C, Escalante P, Falzon D, Garcia-Prats AJ, Gegia M, Gillespie SH, Glynn JR, Goldberg S, Griffith D, Jacobson KR, Johnston JC, Jones-López EC, Khan A, Koh WJ, Kritski A, Lan ZY, Lee JH, Li PZ, Maciel EL, Galliez RM, Merle CSC, Munang M15, Narendran G, Nguyen VN, Nunn A, Ohkado A, Park JS, Phillips PPJ, Ponnuraja C, Reves R, Romanowski K, Seung K, Schaaf HS, Skrahina A, Soolingen DV42, Tabarsi P, Trajman A, Trieu L, Banurekha VV, Viiklepp P, Wang JY, Yoshiyama T, Menzies D.  Comparison of different treatments for isoniazid-resistant tuberculosis: an individual patient data meta-analysis.  Lancet Respir Med. 2018 Apr;6(4):265-275. doi: 10.1016/S2213-2600(18)30078-X.

March 2018

Samuels JP, Sood A, Campbell JR, Ahmad Khan F, Johnston JC8.  Comorbidities and treatment outcomes in multidrug resistant tuberculosis: a systematic review and meta-analysis.  Sci Rep. 2018 Mar 21;8(1):4980. doi: 10.1038/s41598-018-23344-z.

Huang J, Kim D, Shan J, Abu-Arish A, Luo Y, Hanrahan JW.  Most bicarbonate secretion by Calu-3 cells is mediated by CFTR and independent of pendrin.  Physiol Rep. 2018 Mar 16

Yu B, Khan K, Hamid Q, Mardini A, Siddique A, Aguilar-Gonzalez LP, Makhoul G, Alaws H, Genest J, Thanassoulis G, Cecere R, Schwertani A.  Pathological significance of lipoprotein(a) in aortic valve stenosis.  Atherosclerosis. 2018 Mar 15.

Petrof BJ, Sassoon CS. Diaphragm Remodeling during Application of PEEP: A Case of Normal Physiologic Adaptation Gone Awry?  Am J Respir Crit Care Med. 2018 Mar 28. doi: 10.1164/rccm.201803-0518ED. [Epub ahead of print] No abstract available.  

Liang F, Giordano C, Shang D, Li Q, Petrof BJ.  The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmdmdx-4Cv) mice.  PLoS One. 2018 Mar 21;13(3):e0194421. doi: 10.1371/journal.pone.0194421. eCollection 2018.  

Baglole CJ, Liang F, Traboulsi H, de Souza AR, Giordano C, Tauer JT, Rauch F, Petrof BJ.  Pulmonary and diaphragmatic pathology in collagen alpha1 type I (COL1A1) mutant mice with osteogenesis imperfect.  Pediatr Res. 2018 Mar 14. doi: 10.1038/pr.2018.36. [Epub ahead of print] PMID: 29538357 [PubMed – as supplied by publisher]

Shalish W, Latremouille S, Papenburg J, Sant’Anna GM.  Predictors of extubation readiness in preterm infants: a systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed. 2018 Mar 8.

Chalak L, Latremouille S, Mir I, Sánchez PJ, Sant’Anna G.  A review of the conundrum of mild hypoxic-ischemic encephalopathy: Current challenges and moving forward. Early Hum Dev. 2018 May;120:88-94. doi: 10.1016/j.earlhumdev.2018.02.008. Epub 2018 Mar 3.

February 2018

Rocker G, Bourbeau J, Downar J. The New “Opioid Crisis”: Scientific Bias, Media Attention, and Potential Harms for Patients with Refractory Dyspnea.  J Palliat Med. 2018 Feb;21(2):120-122

Frykholm E, Lima VP, Janaudis-Ferreira T, Nyberg A.  Physiological responses to arm versus leg activity in patients with chronic obstructive pulmonary disease: a systematic review protocol. BMJ Open. 2018 Feb 21

Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, Staschke KA, Ghosh A, Gandin V, Topisirovic I, Kristof AS, Hatzoglou M, Simos G, Koromilas AE. Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.  Cell Death Dis. 2018 Feb 15;9(3):254. doi: 10.1038/s41419-018-0326-2.

Dehghani K, Lan Z, Li P, Michelsen SW, Waites S, Benedetti A. Lejeune P, Torrie J, Robinson E, Vejvoda B, Mullah M, Redwood D, Cooper M, Fanning A, Yacoub W, Alvarez GG, Søborg B, Long R, Menzies DDeterminants of tuberculosis trends in six Indigenous populations of the USA, Canada, and Greenland from 1960 to 2014: a population-based study.   2018 Mar;3(3):e133-e142. doi: 10.1016/S2468-2667(18)30002-1. Epub 2018 Feb 14.

Waskiw-Ford M, Wu A, Mainra A, Marchand N, Alhuzaim A, Bourbeau J, Smith BM, Jensen D. Effect of Inhaled Nebulized Furosemide (40 and 120 mg) on Breathlessness during Exercise in the Presence of External Thoracic Restriction in Healthy MenFront Physiol. 2018 Feb 12;9:86. doi: 10.3389/fphys.2018.00086. eCollection 2018.

Hebestreit H, Lands LC, Alarie N, Schaeff J, Karila C, Orenstein DM, Urquhart DS, Hulzebos EHJ, Stein L, Schindler C, Kriemler S, Radtke T; ACTIVATE-CF Study Working Group.  Effects of a partially supervised conditioning programme in cystic fibrosis: an international multi-centre randomised controlled trial (ACTIVATE-CF): study protocol.  BMC Pulm Med. 2018 Feb 8;18(1):31. doi: 10.1186/s12890-018-0596-6.  PMID: 29422091 [PubMed – in process].

Khan N, Divangahi M.  Mycobacterium tuberculosis and HIV Coinfection Brings Fire and Fury to Macrophages.  J Infect Dis. 2018 Feb 8. 

January 2018

Ospina MB, Michas M, Deuchar L, Leigh R, Bhutani M, Rowe BH, Marciniuk D, Goodridge D, Dechman G, Bourbeau J, Balter M, Camp P, Hernandez P, Goldstein RS, Stickland MK.  Development of a patient-centred, evidence-based and consensus-based discharge care bundle for patients with acute exacerbation of chronic obstructive pulmonary disease. BMJ Open Respir Res. 2018 Jan 30;5(1):e000265. doi: 10.1136/bmjresp-2017-000265. eCollection 2018.

Polese B, Gridelet V, Perrier d’Hauterive S, Renard C, Munaut C, Martens H, Vermijlen D, King IL, Jacobs N, Geenen V. Accumulation of IL-17+ Vγ6+ γδ T cells in pregnant mice is not associated with spontaneous abortion. Clin Transl Immunology. 2018 Jan 29;7(1):e1008. doi: 10.1002/cti2.1008. eCollection 2018.

Sehmi R, Lim HF, Mukherjee M, Huang C, Radford K, Newbold P, Boulet LP, Dorscheid D, Martin JG, Nair P. Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma. J Allergy Clin Immunol. 2018 Jan 27. pii: S0091-6749(18)30129-5. doi: 10.1016/j.jaci.2018.01.008. [Epub ahead of print] No abstract available.

Shourian M, Ralph B, Angers I, Sheppard DC, Qureshi ST. Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection. Front Immunol. 2018 Jan 19;8:1987. doi: 10.3389/fimmu.2017.01987. eCollection 2017. PMID: 29403476 [PubMed] Free PMC Article

Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR Jr., Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG; MESA Lung and SPIROMICS investigators. Human airway branch variation and chronic obstructive pulmonary disease.  Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 201715564. doi: 10.1073/pnas.1715564115. [Epub ahead of print]

Panariti A, Baglole CJ, Sanchez V, Eidelman DH, Hussain S, Olivenstein R, Martin JG, Hamid QInterleukin-17A and vascular remodeling in severe asthma; lack of evidence for a direct role. Clin Exp Allergy. 2018 Jan 16. doi: 10.1111/cea.13093. [Epub ahead of print]

Kim JH, Podstawka J, Lou Y, Li L, Lee EKS, Divangahi M, Petri B, Jirik FR, Kelly MM, Yipp BG. Aged polymorphonuclear leukocytes cause fibrotic interstitial lung disease in the absence of regulation by B cells. Nat Immunol. 2018 Jan 15. doi: 10.1038/s41590-017-0030-x. [Epub ahead of print] PMID: 29335647 [PubMed – as supplied by publisher]

Maxwell L, Nandi A, Benedetti A, Devries K, Wagman J, García-Moreno C.  Intimate partner violence and pregnancy spacing: results from a meta-analysis of individual participant time-to-event data from 29 low-and-middle-income countries.  BMJ Glob Health. 2018 Jan 13

Reddy CN, Alhamza H, Chourey S, Ye Q, Gore V, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WSMetabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys. Eur J Pharm Sci. 2018 Jan 12. pii: S0928-0987(18)30028-9. doi: 10.1016/j.ejps.2018.01.021. [Epub ahead of print]

Kessler R, Casan-Clara P, Koehler D, Tognella S, Viejo JL, Dal Negro RW, Díaz-Lobato S, Reissig K, Rodríguez González-Moro JM, Devouassoux G, Chavaillon JM, Botrus P, Arnal JM, Ancochea J, Bergeron-Lafaurie A, De Abajo C, Randerath WJ, Bastian A, Cornelissen CG, Nilius G, Texereau JB, Bourbeau J. COMET: a multicomponent home-based disease-management programme versus routine care in severe COPD.  Eur Respir J. 2018 Jan 11;51(1). pii: 1701612. doi: 10.1183/13993003.01612-2017. Print 2018 Jan.

Kaufmann E, Sanz J, Dunn JL, Khan N, Mendonça LE, Pacis A, Tzelepis F, Pernet E, Dumaine A, Grenier JC, Mailhot-Léonard F, Ahmed E, Belle J, Besla R, Mazer B, King IL, Nijnik A, Robbins CS, Barreiro LB, Divangahi MBCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell. 2018 Jan 11;172(1-2):176-190

Ngwatu BK, Nsengiyumva NP, Oxlade O, Mappin-Kasirer B, Nguyen NL, Jaramillo E, Falzon D, Schwartzman K; Collaborative group on the impact of digital technologies on TB.  The impact of digital health technologies on tuberculosis treatment: a systematic review.  Eur Respir J. 2018 Jan 11;51(1). pii: 1701596

Costiniuk CT, Mehraj V, Routy JP, de Castro C, Wasef N, Jenabian MA, Salahuddin S, Lebouché B, Cox J, Szabo J, Klein M, Lands L, Shapiro AJ.  Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.  AIDS Res Treat. 2018 Jan 9;2018:7645125. doi: 10.1155/2018/7645125. eCollection 2018. PMID: 29552357 [PubMed]

Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Yin D, Ellis G, Ben-Shoshan M, Marenholz I, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk R, Dubois AEJ, Grosche S, Ashley S, Rüschendorf F, Kalb B, Beyer K, Nöthen MM, Lee YA, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D. Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma. J Allergy Clin Immunol. 2018 Jan 8. pii: S0091-6749(18)30025-3. doi: 10.1016/j.jaci.2017.10.047. [Epub ahead of print] No abstract available.

December 2017

Ruffin M, Roussel L, Maillé É, Rousseau S, Brochiero E. Vx-809/Vx-770 treatment reduces inflammatory response to Pseudomonas aeruginosa in primary differentiated cystic fibrosis bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 20. doi: 10.1152/ajplung.00198.2017. [Epub ahead of print]

November 2017

Mazi A, Lands LC, Zielinski D. Methacholine challenge test: Comparison of tidal breathing and dosimeter methods in children. Pediatr Pulmonol. 2017 Nov 27. doi: 10.1002/ppul.23890. [Epub ahead of print]

Radtke T, Hebestreit H, Gallati S, Schneiderman JE, Braun J, Stevens D, Hulzebos EH, Takken T, Boas SR, Urquhart DS, Lands LC, Tejero S, Sovtic A, Dwyer T, Petrovic M, Harris RA, Karila C, Savi D, Usemann J, Mei-Zahav M, Hatziagorou E, Ratjen F, Kriemler S; CFTR-Exercise study group. CFTR Genotype and Maximal Exercise Capacity in Cystic Fibrosis: A Cross-sectional Study.  Ann Am Thorac Soc. 2017 Nov 15. doi: 10.1513/AnnalsATS.201707-570OC. [Epub ahead of print]

Tekwa EW, Nguyen D, Loreau M, Gonzalez A. Defector clustering is linked to cooperation in a pathogenic bacterium. Proc Biol Sci. 2017 Nov 15;284(1866). pii: 20172001. doi: 10.1098/rspb.2017.2001.

Maillé É, Ruffin M, Adam D, Messaoud H, Lafayette SL, McKay G, Nguyen D, Brochiero E. Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells. Front Cell Infect Microbiol. 2017 Nov 10;7:470. doi: 10.3389/fcimb.2017.00470. eCollection 2017.

Desjardins M, Béland M, Dembele M, Lejtenyi D, Drolet JP, Lemire M, Tsoukas C, Ben-Shoshan M, Noya FJD, Alizadehfar R, McCusker CT, Mazer BDModulation of the Interleukin-21 Pathway with Interleukin-4 Distinguishes Common Variable Immunodeficiency Patients with More Non-infectious Clinical Complications.  J Clin Immunol. 2017 Nov 4. doi: 10.1007/s10875-017-0452-0. [Epub ahead of print]

Farahnak S, McGovern TK, Kim R, O’Sullivan M, Chen B, Lee M, Yoshie H, Wang A, Jang J, Al Heialy S, Lauzon AM, Martin JGBasic Fibroblast Growth Factor 2 Is a Determinant of CD4 T Cell-Airway Smooth Muscle Cell Communication through Membrane Conduits. J Immunol. 2017 Nov 1;199(9):3086-3093. doi: 10.4049/jimmunol.1700164. Epub 2017 Sep 18.

October 2017

Pamidi S, Kimoff RJ. Sleep-Disordered Breathing in Pregnancy. Chest. 2017 Oct 21. pii: S0012-3692(17)32906-9. doi: 10.1016/j.chest.2017.10.011. [Epub ahead of print] Review.

Perger E, Inami T, Lyons OD, Alshaer H, Smith S, Floras JS, Logan AG, Arzt M, Cantolla JD, Delgado D, Fitzpatrick M, Fleetham J, Kasai T, Kimoff RJ, Leung RST, Filho GL, Mayer P, Mielniczuk L, Morrison DL, Parati G, Parthasarathy S, Redolfi S, Ryan CM, Series F, Tomlinson GA, Woo A, Bradley TD; ADVENT-HF Investigators. Distinct Patterns of Hyperpnea During Cheyne-Stokes Respiration: Implication for Cardiac Function in Patients With Heart Failure. J Clin Sleep Med. 2017 Oct 18. pii: jc-17-00150. [Epub ahead of print]

Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Ellis G, Ben-Shoshan M, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk RN, Dubois AEJ, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D. Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes c11orf30/EMSY as a genetic risk factor for food allergy. J Allergy Clin Immunol. 2017 Oct 10. pii: S0091-6749(17)31574-9. doi: 10.1016/j.jaci.2017.09.015. [Epub ahead of print]

Divangahi M, Behr MA. Cracking the Vaccine Code in Tuberculosis. Am J Respir Crit Care Med. 2017 Oct 18. doi: 10.1164/rccm.201707-1489PP. [Epub ahead of print]

Ye Q, Chourey S, Wang R, Chintam NR, Gravel S, Powell WS, Rokach J. Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4770-4776. doi: 10.1016/j.bmcl.2017.08.034. Epub 2017 Aug 19.

September 2017

Farahnak S, McGovern TK, Kim R, O’Sullivan M, Chen B, Lee M, Yoshie H, Wang A, Jang J, Al Heialy S, Lauzon AM, Martin JGBasic Fibroblast Growth Factor 2 Is a Determinant of CD4 T Cell-Airway Smooth Muscle Cell Communication through Membrane Conduits. J Immunol. 2017 Sep 18. pii: ji1700164. doi: 10.4049/jimmunol.1700164. [Epub ahead of print]

Paun A, Bergeron ME, Haston CKThe Th1/Th17 balance dictates the fibrosis response in murine radiation-induced lung disease.  Sci Rep. 2017 Sep 14;7(1):11586. doi: 10.1038/s41598-017-11656-5. 

Stana F, Vujovic M, Mayaki D, Leduc-Gaudet JP, Leblanc P, Huck L, Hussain SNADifferential Regulation of the Autophagy and Proteasome Pathways in Skeletal Muscles in Sepsis. Crit Care Med. 2017 Sep;45(9):e971-e979. doi: 10.1097/CCM.0000000000002520.

August 2017

Snarr BD, Qureshi ST, Sheppard DC.  Immune Recognition of Fungal Polysaccharides.  J Fungi (Basel). 2017 Aug 28;3(3). pii: E47. doi: 10.3390/jof3030047. Review.

Julian LM, Delaney SP, Wang Y, Goldberg AA, Doré C, Yockell-Lelièvre J, Tam RY, Giannikou K, McMurray F, Shoichet MS, Harper ME, Henske EP, Kwiatkowski DJ, Darling TN, Moss J, Kristof AS, Stanford WL. Human pluripotent stem cell-derived TSC2-haploinsufficient smooth muscle cells recapitulate features of Lymphangioleiomyomatosis. Cancer Res. 2017 Aug 22. pii: canres.0925.2017. doi: 10.1158/0008-5472.CAN-17-0925. [Epub ahead of print]

Bullone M, Vargas A, Elce Y, Martin JG, Lavoie JP. Fluticasone/salmeterol reduces remodelling and neutrophilic inflammation in severe equine asthma. Sci Rep. 2017 Aug 18;7(1):8843. doi: 10.1038/s41598-017-09414-8.

Salter B, Pray C, Radford K, Martin JG, Nair P. Regulation of human airway smooth muscle cell migration and relevance to asthma. Respir Res. 2017 Aug 16;18(1):156. doi: 10.1186/s12931-017-0640-8. Review.

Liang F, Li T, Azuelos I, Giordano C, Liang H, Hussain SN, Matecki S, Petrof BJVentilator-induced diaphragmatic dysfunction in mdx mice. Muscle Nerve. 2017 Aug 8. doi: 10.1002/mus.25760.

Kristof AS, Petrof BJ, Hamid Q, Kolb M, Landry JS, MacKenzie A, McCormack FX, Murawski IJ, Moss J, Rauch F, Rosas IO, Shapiro AJ, Smith BM, Thomas DY, Trapnell BC, Young LR, Zariwala MA; ATS Assembly on Respiratory Cell and Molecular Biology. An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases. Ann Am Thorac Soc. 2017 Aug;14(8):1239-1247. doi: 10.1513/AnnalsATS.201705-406WS.

July 2017

Boikos C, Joseph L, Scheifele D, Lands LC, De Serres G, Papenburg J, Winters N, Chilvers M, Quach C. Adverse events following live-attenuated intranasal influenza vaccination of children with cystic fibrosis: Results from two influenza seasons. Vaccine. 2017 Jul 31. pii: S0264-410X(17)30976-3. doi: 10.1016/j.vaccine.2017.07.068.

Robichaud A, Fereydoonzad L, Limjunyawong N, Rabold R, Allard B, Benedetti A, Martin JG, Mitzner W. Automated Full-Range Pressure-Volume Curves in Mice and Rats. J Appl Physiol (1985). 2017 Jul 27:jap.00856.2016. doi: 10.1152/japplphysiol.00856.2016.

Zago M, Sheridan JA, Traboulsi H, Hecht E, Zhang Y, Guerrina N, Matthews J, Nair P, Eidelman DH, Hamid Q, Baglole CJLow levels of the AhR in chronic obstructive pulmonary disease (COPD)-derived lung cells increases COX-2 protein by altering mRNA stability. PLoS One. 2017 Jul 27;12(7):e0180881. doi: 10.1371/journal.pone.0180881.

Hamamoto Y, Ano S, Allard B, O’Sullivan M, McGovern TK, Martin JGMK reduces inhaled chlorine triggered AHR and airway inflammation in the mouse. Br J Pharmacol. 2017 Jul 18. doi: 10.1111/bph.13953. [Epub ahead of print]

O’Sullivan MJ, Gabriel E, Panariti A, Park CY, Ijpma G, Fredberg JJ, Lauzon AM, Martin JGEpithelial Cells Induce a Cyclooxygenase-1-dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype. Am J Respir Cell Mol Biol. 2017 Jul 14. doi: 10.1165/rcmb.2016-0427OC. Am J Respir Cell Mol Biol. 2017 Jul 14. doi: 10.1165/rcmb.2016-0427OC.

Pamidi S, Redline S, Rapoport D, Ayappa I, Palombini L, Farre R, Kirkness J, Pépin JL, Polo O, Wellman A, Kimoff RJAn Official American Thoracic Society Workshop Report: Noninvasive Identification of Inspiratory Flow Limitation in Sleep Studies. American Thoracic Society Ad Hoc Committee on Inspiratory Flow Limitation. Ann Am Thorac Soc. 2017 Jul;14(7):1076-1085. doi: 10.1513/AnnalsATS.201704-318WS.

June 2017

Mizutani M, Bérubé J, Ahlgren HG, Bernier J, Matouk E, Nguyen D, Rousseau SCorticosteroid-resistant inflammatory signalling in Pseudomonas infected bronchial cells. ERJ Open Res. 2017 Jun 19;3(2). pii: 00144-2016. doi: 10.1183/23120541.00144-2016.

Ojanguren I, Martin JG, Lemiere C. Thymic Stromal Lymphopoietin: A Promising Target in the Treatment of Asthma? Arch Bronconeumol. 2017 Jun 20. pii: S0300-2896(17)30157-6. doi: 10.1016/j.arbres.2017.05.015. [Epub ahead of print] English, Spanish. No abstract available.

Bin Dhuban K, d’Hennezel E, Nagai Y, Xiao Y, Shao S, Istomine R, Alvarez F, Ben-Shoshan M, Ochs H, Mazer B, Li B, Sekine C, Berezov A, Hancock W, Torgerson TR, Greene MI, Piccirillo CA. Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions. Sci Immunol. 2017 Jun 16;2(12). pii: eaai9297. doi: 10.1126/sciimmunol.aai9297.

Cartee GD, Hepple RT, Bamman MM, Zierath JR. Exercise Promotes Healthy Aging of Skeletal Muscle. Cell Metab. 2016 Jun 14;23(6):1034-47. doi: 10.1016/j.cmet.2016.05.007. Review. PMID: 27304505 [PubMed – indexed for MEDLINE]

Stoppe C, Goetzenich A, Whitman G, Ohkuma R, Brown T, Hatzakorzian R, Kristof A, Meybohm P, Mechanick J, Evans A, Yeh D, McDonald B, Chourdakis M, Jones P, Barton R, Tripathi R, Elke G, Liakopoulos O, Agarwala R, Lomivorotov V, Nesterova E, Marx G, Benstoem C, Lemieux M, Heyland DK. Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery. Crit Care. 2017 Jun 5;21(1):131. doi: 10.1186/s13054-017-1690-5.

Kishta OA, Guo Y, Mofarrahi M, Stana F, Lands LC, Hussain SNA. Pulmonary Pseudomonas aeruginosa infection induces autophagy and proteasome proteolytic pathways in skeletal muscles: effects of a pressurized whey protein-based diet in mice.  Food Nutr Res. 2017 Jun 1;61(1):1325309. doi: 10.1080/16546628.2017.1325309. 

May 2017

Mebert AM, Baglole CJ, Desimone MF, Maysinger D. Nanoengineered silica: Properties, applications and toxicity. Food Chem Toxicol. 2017 May 31. pii: S0278-6915(17)30288-0. doi: 10.1016/j.fct.2017.05.054. [Epub ahead of print].

Stana F, Vujovic M, Mayaki D, Leduc-Gaudet JP, Leblanc P, Huck L, Hussain SNADifferential Regulation of the Autophagy and Proteasome Pathways in Skeletal Muscles in Sepsis. Crit Care Med. 2017 May 22. doi: 10.1097/CCM.0000000000002520. [Epub ahead of print]

Mery VP, Gros P, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea. Neurology. 2017 Mar 21;88(12):1120-1128. doi: 10.1212/WNL.0000000000003738. Epub 2017 Feb 22.

Kaminska M, Noel F, Petrof BJOptimal method for assessment of respiratory muscle strength in neuromuscular disorders using sniff nasal inspiratory pressure (SNIP). PLoS One. 2017 May 16;12(5):e0177723. doi: 10.1371/journal.pone.0177723. eCollection 2017.

Shalaby KH, Al-Heialy S, Tsuchiya K, Farahnak S, McGovern TK, Risse PA, Suh WK, Qureshi ST, Martin JGThe TLR4-TRIF pathway can protect against the development of experimental allergic asthma. Immunology. 2017 May 14. doi: 10.1111/imm.12755. [Epub ahead of print]

Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WSIn vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys. Biochem Pharmacol. 2017 May 2. pii: S0006-2952(17)30248-4. doi: 10.1016/j.bcp.2017.04.031. [Epub ahead of print]

April 2017

Wang W, Qu X, Dang X, Shang D, Yang L, Li Y, Xu D, Martin JG, Hamid Q, Liu J, Chang Y. Human β-defensin-3 Induces IL-8 Release and Apoptosis in Airway Smooth Muscle Cells. Clin Exp Allergy. 2017 Apr 24. doi: 10.1111/cea.12943. [Epub ahead of print]

Summerhill EM, Hoyle GW, Jordt SE, Jugg BJ, Martin JG, Matalon S, Patterson SE, Prezant DJ, Sciuto AM, Svendsen ER, White CW, Veress LA; ATS Terrorism and Inhalational Disasters Section of the Environmental, Occupational, and Population Health Assembly. An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters: Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness. Ann Am Thorac Soc. 2017 Apr 18. doi: 10.1513/AnnalsATS.201704-297WS. [Epub ahead of print]

Sterling M, Al-Ismaili Z, McMahon KR, Piccioni M, Pizzi M, Mottes T, Lands LC, Abish S, Fleming AJ, Bennett MR, Palijan A, Devarajan P, Goldstein SL, O’Brien MM, Zappitelli M. Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy. Pediatr Blood Cancer. 2017 Apr 18. doi: 10.1002/pbc.26538. [Epub ahead of print]

Zhao X, Khan N, Gan H, Tzelepis F, Nishimura T, Park SY, Divangahi M, Remold HG. Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages. Mucosal Immunol. 2017 Apr 12. doi: 10.1038/mi.2017.12. [Epub ahead of print]

Downey J, Pernet E, Coulombe F, Allard B, Meunier I, Jaworska J, Qureshi S, Vinh DC, Martin JG, Joubert P, Divangahi MRIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection. PLoS Pathog. 2017 Apr 14;13(4):e1006326. doi: 10.1371/journal.ppat.1006326. [Epub ahead of print]

Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Jiang HY, Bourdeau F, Beauchamp A, Mancini U, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE. Gram-Positive Pneumonia Augments Non-Small Cell Lung Cancer Metastasis Via Host Toll-like Receptor 2 Activation. Int J Cancer. 2017 Apr 12. doi: 10.1002/ijc.30734. [Epub ahead of print]

Heyland DK, Weijs PJ, Coss-Bu JA, Taylor B, Kristof AS, O’Keefe GE, Martindale RG. Protein Delivery in the Intensive Care Unit: Optimal or Suboptimal? Nutr Clin Pract. 2017 Apr;32(1_suppl):58S-71S. doi: 10.1177/0884533617691245. Epub 2017 Mar 1.

March 2017

Poon AH, Choy DF, Chouiali F, Ramakrishnan RK, Mahboub B, Audusseau S, Mogas A, Harris JM, Arron JR, Laprise C, Hamid QIncreased Autophagy-Related 5 Gene Expression Is Associated with Collagen Expression in the Airways of Refractory Asthmatics. Front Immunol. 2017 Mar 29;8:355. doi: 10.3389/fimmu.2017.00355. eCollection 2017.

Lands LCDyspnea in Children: What is driving it and how to approach it. Paediatr Respir Rev. 2017 Mar 31. pii: S1526-0542(17)30036-2. doi: 10.1016/j.prrv.2017.03.013. [Epub ahead of print] Review.

Ijpma G, Panariti A, Lauzon AM, Martin JGDirectional preference of airway smooth muscle mass increase in human asthmatic airways. Am J Physiol Lung Cell Mol Physiol. 2017 Mar 30:ajplung.00353.2016. doi: 10.1152/ajplung.00353.2016. [Epub ahead of print]

Harel S, Mayaki D, Sanchez V, Hussain SNNOX2, NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells. Vascul Pharmacol. 2017 Mar 25. pii: S1537-1891(16)30194-X. doi: 10.1016/j.vph.2017.03.002. [Epub ahead of print]

MacMillan NJ, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe RT, Baril J, Carver TE, Andersen RE, Richard R, Perrault H, Bourbeau J, Hepple RT, Taivassalo T. Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease. Front Physiol. 2017 Mar 3;8:114. doi: 10.3389/fphys.2017.00114. eCollection 2017 Mar 3.

Boikos C, Papenburg J, Martineau C, Joseph L, Scheifele D, Chilvers M, Lands LC, De Serres G, Quach C. Viral Interference and the Live-attenuated Intranasal Influenza Vaccine: Results from a Pediatric Cohort with Cystic Fibrosis. Hum Vaccin Immunother. 2017 Mar 8:0. doi: 10.1080/21645515.2017.1287641. [Epub ahead of print]

Siddiqui S, Lustig A, Carter A, Sankar M, Daimon CM, Premont RT, Etienne H, van Gastel J, Azmi A, Janssens J, Becker KG, Zhang Y, Wood W, Lehrmann E, Martin JG, Martin B, Taub DD, Maudsley S. Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption. Aging (Albany NY). 2017 Mar 4. doi: 10.18632/aging.101185. [Epub ahead of print]

February 2017

Moussette S, Al Tuwaijri A, Kohan-Ghadr HR, Elzein S, Farias R, Bérubé J, Ho B, Laprise C, Goodyer CG, Rousseau S, Naumova AK. Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells. PLoS One. 2017 Feb 27;12(2):e0172707. doi: 10.1371/journal.pone.0172707. eCollection 2017.

Iu M, Zago M, de Souza AR, Bouttier M, Pareek S, White JH, Hamid Q, Eidelman DH, Baglole CJRelB attenuates cigarette smoke extract-induced apoptosis in association with transcriptional regulation of the aryl hydrocarbon receptor. Free Radic Biol Med. 2017 Feb 27. pii: S0891-5849(17)30117-X. doi: 10.1016/j.freeradbiomed.2017.02.045. [Epub ahead of print]

Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC. Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A. 2017 Feb 21. pii: 201700997. doi: 10.1073/pnas.1700997114. [Epub ahead of print]

Massoud AH, Kaufman GN, Xue D, Béland M, Dembele M, Piccirillo CA, Mourad W, Mazer BDPeripherally Generated Foxp3+ Regulatory T Cells Mediate the Immunomodulatory Effects of IVIg in Allergic Airways Disease. J Immunol. 2017 Feb 20. pii: 1502361. doi: 10.4049/jimmunol.1502361. [Epub ahead of print]

Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong MC, Cohen-Blanchet A, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC. Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency. J Allergy Clin Immunol. 2017 Feb 16. pii: S0091-6749(17)30240-3. doi: 10.1016/j.jaci.2017.02.002. [Epub ahead of print]

Mery VP, Gros P, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea. Neurology. 2017 Feb 22. pii: 10.1212/WNL.0000000000003738. doi: 10.1212/WNL.0000000000003738. [Epub ahead of print]

Martins D, Nguyen DStimulating Central Carbon Metabolism to Re-sensitize Pseudomonas aeruginosa to Aminoglycosides. Cell Chem Biol. 2017 Feb 16;24(2):122-124. doi: 10.1016/j.chembiol.2017.02.004.

Hildebrand KJ, Abrams EM, Vander Leek TK, Upton JE, Mack DP, Kirste L, McCusker C, Kapur S. Primum non nocere – first do no harm. And then feed peanut. Allergy Asthma Clin Immunol. 2017 Feb 8;13:7. doi: 10.1186/s13223-017-0180-2.

Nair P, Martin JG, Cockcroft DC, Dolovich M, Lemiere C, Boulet LP, O’Byrne PM. Airway Hyperresponsiveness in Asthma: Measurement and Clinical Relevance. J Allergy Clin Immunol Pract. 2017 Feb 2. pii: S2213-2198(16)30623-7. doi: 10.1016/j.jaip.2016.11.030. [Epub ahead of print] Review.

Najmeh S, Cools-Lartigue J, Rayes RF, Gowing S, Vourtzoumis P, Bourdeau F, Giannias B, Berube J, Rousseau S, Ferri LE, Spicer JD. Neutrophil Extracellular Traps sequester circulating tumor cells via β1-integrin mediated interactions. Int J Cancer. 2017 Feb 8. doi: 10.1002/ijc.30635. [Epub ahead of print]

Meunier I, Kaufmann E, Downey J, Divangahi MUnravelling the networks dictating host resistance versus tolerance during pulmonary infections. Cell Tissue Res. 2017 Feb 6. doi: 10.1007/s00441-017-2572-5. [Epub ahead of print] Review.

Vassilakopoulos T, Petrof BJA Stimulating Approach to Ventilator-induced Diaphragmatic Dysfunction. Am J Respir Crit Care Med. 2017 Feb 1;195(3):281-282. doi: 10.1164/rccm.201608-1619ED.

January 2017

King IL, Mohrs K, Meli AP, Downey J, Lanthier P, Tzelepis F, Fritz JH, Tumanov AV, Divangahi M, Leadbetter EA, Mohrs M. Intestinal helminth infection impacts the systemic distribution and function of the naive lymphocyte pool. Mucosal Immunol. 2017 Jan 25. doi: 10.1038/mi.2016.127. [Epub ahead of print]

Traboulsi H, Guerrina N, Iu M, Maysinger D, Ariya P, Baglole CJInhaled Pollutants: The Molecular Scene behind Respiratory and Systemic Diseases Associated with Ultrafine Particulate Matter. Int J Mol Sci. 2017 Jan 24;18(2). pii: E243. doi: 10.3390/ijms18020243. Review.

Martin JG, Panariti A. Asthma Phenotypes; Do They Matter? Arch Bronconeumol. 2017 Jan 23. pii: S0300-2896(16)30344-1. doi: 10.1016/j.arbres.2016.11.016. [Epub ahead of print]

Rammal A, Tewfik M, Rousseau SDifferences in RANTES and IL-6 levels among chronic rhinosinusitis patients with predominant gram-negative and gram-positive infection. J Otolaryngol Head Neck Surg. 2017 Jan 17;46(1):7. doi: 10.1186/s40463-016-0183-x.

Rogers S, de Souza AR, Zago M, Iu M, Guerrina N, Gomez A, Matthews J, Baglole CJAryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure. Sci Rep. 2017 Jan 12;7:40539. doi: 10.1038/srep40539.

Dang X, Qu X, Wang W, Liao C, Li Y, Zhang X, Xu D, Baglole CJ, Shang D, Chang Y. Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease. Respir Res. 2017 Jan 5;18(1):4. doi: 10.1186/s12931-016-0486-5.

Roussel L, Rousseau SExposure of airway epithelial cells to Pseudomonas aeruginosa biofilm-derived quorum sensing molecules decrease the activity of the anti-oxidant response element bound by NRF2. Biochem Biophys Res Commun. 2017 Jan 3. pii: S0006-291X(17)30009-8. doi: 10.1016/j.bbrc.2017.01.009. [Epub ahead of print]

Anekwe DE, Koo KK, de Marchie M, Goldberg P, Jayaraman D, Spahija J. Interprofessional Survey of Perceived Barriers and Facilitators to Early Mobilization of Critically Ill Patients in Montreal, Canada. J Intensive Care Med. 2017 Jan 1:885066617696846. doi: 10.1177/0885066617696846. [Epub ahead of print]

Nagendra Reddy C, Ye Q, Patel P, Sivendran S, Chourey S, Wang R, Anumolu JR, Grant GE, Powell WS, Rokach J. Design and synthesis of affinity chromatography ligands for the purification of 5-hydroxyeicosanoid dehydrogenase. Bioorg Med Chem. 2017 Jan 1;25(1):116-125. doi: 10.1016/j.bmc.2016.10.017. Epub 2016 Oct 15.

December 2016

Perez EE, Orange JS, Bonilla F, Chinen J, Chinn IK, Dorsey M, El-Gamal Y, Harville TO, Hossny E, Mazer B, Nelson R, Secord E, Jordan SC, Stiehm ER, Vo AA, Ballow M. Update on the use of immunoglobulin in human disease: A review of evidence. J Allergy Clin Immunol. 2016 Dec 24. pii: S0091-6749(16)31141-1. doi: 10.1016/j.jaci.2016.09.023. [Epub ahead of print]

Goldberg AA, Nkengfac B, Sanchez AM, Moroz N, Qureshi ST, Koromilas AE, Wang S, Burelle Y, Hussain SN, Kristof ASRegulation of ULK1 expression and autophagy by STAT1. J Biol Chem. 2016 Dec 23. pii: jbc.M116.771584. doi: 10.1074/jbc.M116.771584. [Epub ahead of print]

Roussel L, LaFayette S, Nguyen D, Baglole CJ, Rousseau SDifferential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to Pseudomonas aeruginosa. Front Cell Dev Biol. 2016 Dec 22;4:148. doi: 10.3389/fcell.2016.00148.

Pothoven KL, Norton JE, Suh LA, Carter RG, Harris KE, Biyasheva A, Welch K, Shintani-Smith S, Conley DB, Liu MC, Kato A, Avila PC, Hamid Q, Grammer LC 3rd, Peters AT, Kern RC, Tan BK, Schleimer RP. Neutrophils are a major source of the epithelial barrier disrupting cytokine Oncostatin M in mucosal airways disease. J Allergy Clin Immunol. 2016 Dec 16. pii: S0091-6749(16)31462-2. doi: 10.1016/j.jaci.2016.10.039. [Epub ahead of print]

Falegan OS, Vogel HJ, Hittel DS, Koch LG, Britton SL, Hepple RT, Shearer J. High aerobic capacity mitigates changes in the plasma metabolic profile associated with aging. J Proteome Res. 2016 Dec 12. [Epub ahead of print]

Xue D, Desjardins M, Kaufman GN, Béland M, Al-Tamemi S, Ahmed E, Tao S, Friedel RH, Mourad W, Mazer BDSemaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses. Front Immunol. 2016 Dec 7;7:558. doi: 10.3389/fimmu.2016.00558.

November 2016

Xue D, Kaufman GN, Dembele M, Beland M, Massoud AH, Mindt BC, Fiter R, Fixman ED, Martin JG, Friedel RH, Divangahi M, Fritz JH, Mazer BDSemaphorin 4C Protects against Allergic Inflammation: Requirement of Regulatory CD138+ Plasma Cells. J Immunol. 2016 Nov 23. pii: 1600831. [Epub ahead of print]

Magder S, Serri K, Verscheure S, Chauvin R, Goldberg PActive Expiration and the Measurement of Central Venous Pressure. J Intensive Care Med. 2016 Nov 20. pii: 0885066616678578. [Epub ahead of print]

Ano S, Panariti A, Allard B, O’Sullivan M, McGovern TK, Hamamoto Y, Ishii Y, Yamamoto M, Powell WS, Martin JGInflammation and airway hyperresponsiveness after chlorine exposure are prolonged by Nrf2 deficiency in mice. Free Radic Biol Med. 2016 Nov 12. pii: S0891-5849(16)31040-1. doi: 10.1016/j.freeradbiomed.2016.11.017. [Epub ahead of print]

MacFadden-Murphy E, Roussel L, Martel G, Bérubé J, Rousseau SDecreasing SMPD1 activity in BEAS-2B bronchial airway epithelial cells results in increased NRF2 activity, cytokine synthesis and neutrophil recruitment. Biochem Biophys Res Commun. 2016 Nov 16. pii: S0006-291X(16)31950-7. doi: 10.1016/j.bbrc.2016.11.087. [Epub ahead of print]

Altit G, Dancea A, Renaud C, Perreault T, Lands LC, Sant’Anna G. Pathophysiology, screening and diagnosis of pulmonary hypertension in infants with bronchopulmonary dysplasia – A review of the literature. Paediatr Respir Rev. 2016 Nov 9. pii: S1526-0542(16)30125-7. doi: 10.1016/j.prrv.2016.11.002. [Epub ahead of print]

October 2016

Fitzgerald DA, Eber E, Lands LCSecondary Pulmonary Hypertension: Who to consider, how to confirm and when to follow-up. Paediatr Respir Rev. 2016 Oct 31. pii: S1526-0542(16)30122-1. doi: 10.1016/j.prrv.2016.10.008. [Epub ahead of print]

Das S, Miller M, Beppu AK, Mueller J, McGeough MD, Vuong C, Karta MR, Rosenthal P, Chouiali F, Doherty TA, Kurten RC, Hamid Q, Hoffman HM, Broide DH. GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation. Proc Natl Acad Sci U S A. 2016 Oct 31. pii: 201610433. [Epub ahead of print]

Pai M, Behr MA, Dowdy D, Dheda K, Divangahi M, Boehme CC, Ginsberg A, Swaminathan S, Spigelman M, Getahun H, Menzies D, Raviglione M. Tuberculosis. Nat Rev Dis Primers. 2016 Oct 27;2:16076. doi: 10.1038/nrdp.2016.76.

Cossette C, Chourey S, Ye Q, Nagendra Reddy C, Gore V, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WSPharmacokinetics and metabolism of selective oxoeicosanoid (OXE) receptor antagonists and their effects on 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE)-induced granulocyte activation in monkeys. J Med Chem. 2016 Oct 21. PMID: 27766872. DOI:10.1021/acs.jmedchem.6b00895

Matouk E, Nguyen D, Benedetti A, Bernier J, Gruber J, Landry J, Rousseau S, Ahlgren HG, Lands LC, Wojewodka G, Radzioch D. C-Reactive Protein in Stable Cystic Fibrosis: An Additional Indicator of Clinical Disease Activity and Risk of Future Pulmonary Exacerbations. J Pulm Respir Med. 2016 Oct 14;6(5):1000375. doi: 10.4172/2161-105X.1000375.

Gouspillou G, Hepple RTEditorial: Mitochondria in Skeletal Muscle Health, Aging and Diseases. Front Physiol. 2016 Oct 6;7:446. No abstract available.

Lau L, Al-Ismaili Z, Harel-Sterling M, Pizzi M, Caldwell JS, Piccioni M, Lands LC, Mottes T, Devarajan P, Goldstein SL, Bennett MR, Zappitelli M. Serum cystatin C for acute kidney injury evaluation in children treated with aminoglycosides. Pediatr Nephrol. 2016 Oct 14.

Genest J, Hébert TE, Martin JThe Louis and Artur Lucian Award in Cardiovascular Diseases at McGill University. Circ Res. 2016 Oct 14;119(9):975-977.

Narayanapillai SC, Lin SH, Leitzman P, Upadhyaya P, Baglole CJ, Xing C. Dihydromethysticin (DHM) blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced O6-methylguanine independent of aryl hydrocarbon receptor (AhR) in C57BL/6 female mice. Chem Res Toxicol. 2016 Oct 11. PMID: 27728767 [PubMed]

Codere-Maruyama T, Schricker T, Shum-Tim D, Wykes L, Nitschmann E, Guichon C, Kristof AS, Hatzakorzian R. Hyperinsulinemic-normoglycemic clamp administered together with amino acids induces anabolism after cardiac surgery. Am J Physiol Regul Integr Comp Physiol. 2016 Oct 5:ajpregu.00334.2016.

September 2016

Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan N, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RTDenervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol. 2016 Sep 13. doi: 10.1113/JP272487. [Epub ahead of print]

Al-Kufaidy R, Vazquez-Tello A, BaHammam AS, Hamid Q, Al-Muhsen S, Halwani R. IL-17 enhances the migration of B cells during asthma by inducing CXCL13 chemokine production in structural lung cells. J Allergy Clin Immunol. 2016 Sep 14. pii: S0091-6749(16)30958-7. doi: 10.1016/j.jaci.2016.07.037. [Epub ahead of print]

Aare S, Spendiff S, Vuda M, Elkrief D, Perez A, Wu Q, Mayaki D, Hussain SN, Hettwer S, Hepple RTFailed reinnervation in aging skeletal muscle. Skelet Muscle. 2016 Sep 1;6(1):29. doi: 10.1186/s13395-016-0101-y. eCollection 2016.

St-Jean-Pelletier F, Pion CH, Leduc-Gaudet JP, Sgarioto N, Zovilé I, Barbat-Artigas S, Reynaud O, Alkaterji F, Lemieux FC, Grenon A, Gaudreau P, Hepple RT, Chevalier S, Belanger M, Morais JA, Aubertin-Leheudre M, Gouspillou G. The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men. J Cachexia Sarcopenia Muscle. 2016 Sep 2. doi: 10.1002/jcsm.12139. [Epub ahead of print]

August 2016

Boikos C, Joseph L, Martineau C, Papenburg J, Scheifele D, Lands LC, De Serres G, Chilvers M, Quach C. Influenza Virus Detection Following Administration of Live-Attenuated Intranasal Influenza Vaccine in Children With Cystic Fibrosis and Their Healthy Siblings. Open Forum Infect Dis. 2016 Aug 30;3(4):ofw187.

Srinivasa BT, Restori KH, Shan J, Cyr L, Xing L, Lee S, Ward BJ, Fixman EDSTAT6 inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection. J Leukoc Biol. 2016 Aug 26. pii: jlb.4A0215-062RR. [Epub ahead of print]

July 2016

Matecki S, Dridi H, Jung B, Saint N, Reiken SR, Scheuermann V, Mrozek S, Santulli G, Umanskaya A, Petrof BJ, Jaber S, Marks AR, Lacampagne A. Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation. Proc Natl Acad Sci U S A. 2016 Jul 25. pii: 201609707. [Epub ahead of print]

Goldberg AA, Joung KB, Mansuri A, Kang Y, Echavarria R, Nikolajev L, Sun Y, Yu JJ, Laporte SA, Schwertani A, Kristof ASOncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2. Oncotarget. 2016 Jul 21. doi: 10.18632/oncotarget.10748. [Epub ahead of print]

Hebestreit H, Arets HG, Aurora P, Boas S, Cerny F, Hulzebos EH, Karila C, Lands LC, Lowman JD, Swisher A, Urquhart DS; Cystic Fibrosis Exercise Working Group. Authors’ Reply: Statement on Exercise testing in Cystic Fibrosis. Respiration. 2016 Jul 1;92(1):63-64. [Epub ahead of print]

June 2016

Schnúr A, Hegyi P, Rousseau S, Lukacs GL, Veit G. Epithelial Anion Transport as Modulator of Chemokine Signaling. Mediators Inflamm. 2016;2016:7596531. Epub 2016 Jun 12. Review.

Boisvert AA, Cheng MP, Sheppard DC, Nguyen D. Microbial Biofilms in Pulmonary and Critical Care Diseases. Ann Am Thorac Soc. 2016 Jun 27. [Epub ahead of print]

Chan W, Ismail H, Mayaki D, Sanchez V, Tiedemann K, Davis EC, Hussain SNFibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells. PLoS One. 2016 Jun 15;11(6):e0156994. doi: 10.1371/journal.pone.0156994. eCollection 2016.

Cartee GD, Hepple RT, Bamman MM, Zierath JR. Exercise Promotes Healthy Aging of Skeletal Muscle. Cell Metab. 2016 Jun 14;23(6):1034-47. doi: 10.1016/j.cmet.2016.05.007. Review.

Gershon AS, Maclagan LC, Luo J, To T, Kendzerska T, Stanbrook MB, Bourbeau J, Etches J, Aaron SD.  End of Life Strategies Among Patients with Advanced Chronic Obstructive Pulmonary Disease (COPD) Am J Respir Crit Care Med. 2018 Jun 11. doi: 10.1164/rccm.201803-0592OC. [Epub ahead of print]

May 2016

Taivassalo T, Hussain SNContribution of the Mitochondria to Locomotor Muscle Dysfunction in Patients With COPD. Chest. 2016 May;149(5):1302-12. doi: 10.1016/j.chest.2015.11.021. Epub 2015 Dec 12. Review.

Silva-Barrios S, Smans M, Duerr CU, Qureshi ST, Fritz JH, Descoteaux A, Stäger S. Innate Immune B Cell Activation by Leishmania donovani Exacerbates Disease and Mediates Hypergammaglobulinemia. Cell Rep. 2016 May 31. pii: S2211-1247(16)30611-8. doi: 10.1016/j.celrep.2016.05.028.

Hathroubi S, Mekni MA, Domenico P, Nguyen D, Jacques M. Biofilms: Microbial Shelters Against Antibiotics. Microb Drug Resist. 2016 May 23. [Epub ahead of print]

McGovern T, Goldberger M, Chen M, Allard B, Hamamoto Y, Kanaoka Y, Austen KF, Powell WSMartin JGCysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma. J Immunol. 2016 May 25. pii: 1501084. [Epub ahead of print]

Walsh CJ, Zaihra T, Benedetti A, Fugère C, Olivenstein R, Lemière C, Hamid QMartin JGExacerbation risk in severe asthma is stratified by inflammatory phenotype using longitudinal measures of sputum eosinophils. Clin Exp Allergy. 2016 May 23. doi: 10.1111/cea.12762.

Ruffin M, Bilodeau C, Maillé É, LaFayette SL, McKay GA, Trinh NT, Beaudoin T, Desrosiers MY, Rousseau SNguyen D, Brochiero E. Quorum-sensing inhibition abrogates the deleterious impact of Pseudomonas aeruginosa on airway epithelial repair. FASEB J. 2016 May 13. pii: fj.201500166R. [Epub ahead of print]

Zaihra T, Walsh CJ, Ahmed S, Fugère C, Hamid QA, Olivenstein R, Martin JG, Benedetti A. Phenotyping of difficult asthma using longitudinal physiological and biomarker measurements reveals significant differences in stability between clusters. BMC Pulm Med. 2016 May 10;16(1):74. doi: 10.1186/s12890-016-0232-2.

Withington DE, Fontela PS, Harrington KP, Lands LCPerioperative Steroids in Pediatric Cardiopulmonary Bypass: We Still Do Not Have All the Answers. Pediatr Crit Care Med. 2016 May;17(5):475. doi: 10.1097/PCC.0000000000000679.

April 2016

Mak DY, Sykes J, Stephenson AL, Lands LCThe benefits of newborn screening for cystic fibrosis: The Canadian experience. J Cyst Fibros. 2016 Apr 21. pii: S1569-1993(16)30018-2. doi: 10.1016/j.jcf.2016.04.001. [Epub ahead of print]

Dessalle K, Narayanan V, Kyoh S, Mogas A, Halayko AJ, Nair P, Baglole CJEidelman DH, Ludwig MSHamid QHuman bronchial and parenchymal fibroblasts display differences in basal inflammatory phenotype and response to IL-17A. Clin Exp Allergy. 2016 Apr 15. doi: 10.1111/cea.12744. [Epub ahead of print]

Pamidi S, Marc I, Simoneau G, Lavigne L, Olha A, Benedetti A, Sériès F, Fraser W, Audibert F, Bujold E, Gagnon R, Schwartzman K,  Kimoff RJMaternal sleep-disordered breathing and the risk of delivering small for gestational age infants: a prospective cohort study. Thorax. 2016 Apr 15. pii: thoraxjnl-2015-208038. doi: 10.1136/thoraxjnl-2015-208038. [Epub ahead of print]

Dauletbaev N, Lands LCCould relative abundance of airway lipoxins be the clue to restore corticosteroid sensitivity in severe asthma? J Allergy Clin Immunol. 2016 Apr 12. pii: S0091-6749(16)00377-8. doi: 10.1016/j.jaci.2016.02.012. [Epub ahead of print] No abstract available.

Dos Santos C, Hussain SN, Mathur S, Picard M, Herridge M, Correa J, Bain A, Guo Y, Advani A, Advani SL, Tomlinson G, Katzberg H, Streutker CJ, Cameron JI, Schols A, Gosker H, Batt J; MEND ICU group, the RECOVER Program investigators and the Canadian Critical Care Translational Biology Group. Mechanisms of Chronic Muscle Wasting and Dysfunction After an Intensive Care Unit Stay: A Pilot Study. Am J Respir Crit Care Med. 2016 Apr 8. [Epub ahead of print]

Tarnopolsky M, Katzberg H, Petrof BJ, Sirrs S, Sarnat HB, Myers K, Dupré N, Dodig D, Genge A, Venance SL, Korngut L, Raiman J, Khan A. Pompe Disease: Diagnosis and Management. Evidence-Based Guidelines from a Canadian Expert Panel. Can J Neurol Sci. 2016 Apr 8:1-14. [Epub ahead of print]

Lands LC, Stanojevic S. Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis. Cochrane Database Syst Rev. 2016 Apr 7;4:CD001505. [Epub ahead of print] Review.

March 2016

Hussain SN, Cornachione AS, Guichon C, Al Khunaizi A, de Souza Leite F, Petrof BJ, Mofarrahi M, Moroz N, de Varennes B,  Goldberg P, Rassier DE. Prolonged controlled mechanical ventilation in humans triggers myofibrillar contractile dysfunction and myofilament protein loss in the diaphragm. Thorax. 2016 Mar 31. pii: thoraxjnl-2015-207559. doi: 10.1136/thoraxjnl-2015-207559. [Epub ahead of print]

O’Keefe AW, Halbrich M, Ben-Shoshan M, McCusker CPrimary immunodeficiency for the primary care provider. Paediatr Child Health. 2016 Mar;21(2):e10-4. Review.

Poon AH, Hamid QSevere Asthma: Have We Made Progress? Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S68-77. doi: 10.1513/AnnalsATS.201508-514MG.

Hepple RTImpact of Aging on Mitochondrial Function in Cardiac and Skeletal Muscle. Free Radic Biol Med. 2016 Mar 23. pii: S0891-5849(16)00123-4. doi: 10.1016/j.freeradbiomed.2016.03.017. [Epub ahead of print]

Power GA, Allen MD, Gilmore KJ, Stashuk DW, Doherty TJ, Hepple RT, Taivassalo T, Rice CL. Motor unit number and transmission stability in octogenarian world class athletes: Can age-related deficits be outrun?  J Appl Physiol (1985). 2016 Mar 24:jap.00149.2016. doi: 10.1152/japplphysiol.00149.2016.

Miller M, Esnault S, Kurten RC, Kelly EA, Beppu A, Das S, Rosenthal P, Ramsdell J, Croft M, Zuraw B, Jarjour N, Hamid Q, Broide DH. Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma.  J Allergy Clin Immunol. 2016 Mar 18. pii: S0091-6749(16)00256-6. doi: 10.1016/j.jaci.2016.01.019.

Lauzon AMMartin JGAirway hyperresponsiveness; smooth muscle as the principal actor. F1000Res. 2016 Mar 9;5. pii: F1000 Faculty Rev-306. doi: 10.12688/f1000research.7422.1. eCollection 2016.

Gohal G, McCusker CMazer B, Alizadehfar R, Lejtenyi D, Ben-Shoshan M.  T-cell receptor phenotype pattern in atopic children using commercial fluorescently labeled antibodies against 21 human class-specific v segments for the tcrβ chain (vβ) of peripheral blood: a cross sectional study. Allergy Asthma Clin Immunol. 2016 Mar 2;12:10. doi: 10.1186/s13223-016-0115-3. eCollection 2016.

February 2016

Labonté LE, Bourbeau J, Daskalopoulou SS, Zhang M, Coulombe P, Garland K, Baglole CJClub Cell-16 and RelB as Novel Determinants of Arterial Stiffness in Exacerbating COPD Patients. PLoS One. 2016 Feb 25;11(2):e0149974. doi: 10.1371/journal.pone.0149974.

Konokhova Y, Spendiff S, Jagoe RT, Aare S, Kapchinsky S, MacMillan NJ, Rozakis P, Picard M, Aubertin-Leheudre M, Pion CH, Bourbeau J, Hepple RT, Taivassalo T. Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle. Skelet Muscle. 2016 Feb 18;6:10.

January 2016

Mojumdar K, Giordano C, Lemaire C, Liang F,  Divangahi MQureshi STPetrof BJDivergent impact of Toll-like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy. J Pathol. 2016 Jan 21. doi: 10.1002/path.4689. [Epub ahead of print].

Bazett M, Bergeron ME, Haston CKStreptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model. Sci Rep. 2016 Jan 12;6:19189. doi: 10.1038/srep19189.

Farias R, Rousseau S. The TAK1→IKKβ→TPL2→MKK1/MKK2 Signaling Cascade Regulates IL-33 Expression in Cystic Fibrosis Airway Epithelial Cells Following Infection by Pseudomonas aeruginosa. Front Cell Dev Biol. 2016 Jan 11;3:87. doi: 10.3389/fcell.2015.00087.

Klionsky DJ, Hamid Q, Hussain SNPetrof BJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016 Jan 2;12(1):1-222.

 

 

 

pulmonary research publications by Meakins-Christie Laboratories faculty

Publications are organized by date that notification was received from PubMed

View most recent publications

December 2015

Polese B, Gridelet V, Perrier d’Hauterive S, Renard C, Munaut C, Martens H, Vermijlen D, King IL, Jacobs N, Geenen V. Accumulation of IL-17+ Vγ6+ γδ T cells in pregnant mice is not associated with spontaneous abortion.  Clin Transl Immunology. 2018 Jan 29;7(1):e1008. doi: 10.1002/cti2.1008. eCollection 2018.

Shilo NR, Alawadi A, Allard-Coutu A, Robitaille N, Pastore Y, Bérubé D, Jacob SV, Abish S, Dauletbaev N,Lands LCAirway hyperreactivity is frequent in non-asthmatic children with sickle cell disease. Pediatr Pulmonol. 2015 Dec 30. doi: 10.1002/ppul.23374. [Epub ahead of print]

Sehmi R, Smith SG, Kjarsgaard M, Radford K, Boulet LP, Lemiere C, Prazma CM, Ortega H, Martin JG, Nair P. Role of Local Eosinophilopoietic Processes in the Development of Airway Eosinophilia in Prednisone-dependent Severe Asthma. Clin Exp Allergy. 2015 Dec 18. doi: 10.1111/cea.12695. [Epub ahead of print]

Zysman-Colman Z, Lands LCWhole Body Plethysmography: Practical Considerations. Paediatr Respir Rev. 2015 Dec 8.

Power GA, Minozzo FC, Spendiff S, Filion ME, Konokhova Y, Purves-Smith M, Pion C, Aubertln-Leheudre M, Morais JA, Herzog W, Hepple RT, Taivassalo T, Rassier DE. Reduction in single muscle fiber rate of force development with aging is not attenuated in world class older masters athletes. Am J Physiol Cell Physiol. 2015 Dec 2:ajpcell.00289.2015

November 2015

Petrof BJHussain SNVentilator-induced diaphragmatic dysfunction: what have we learned?Curr Opin Crit Care. 2015 Nov 30.  [Epub ahead of print]

Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J, Eva MM, Gauchat JF, Qureshi STMazer BD, Mossman KL, Malo D, Gamero AM, Vidal SM, King IL, Sarfati M, Fritz JH. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nat Immunol. 2015 Nov 23. doi: 10.1038/ni.3308.

Dauletbaev N, Das M, Cammisano M, Chen H, Singh S, Kooi C, Leigh R, Beaudoin T, Rousseau SLands LCRhinovirus Load Is High despite Preserved Interferon-β Response in Cystic Fibrosis Bronchial Epithelial Cells. PLoS One. 2015 Nov 23;10(11):e0143129. doi: 10.1371/journal.pone.0143129.

Depner M, Fuchs S, Raabe J, Frede N, Glocker C, Doffinger R, Gkrania-Klotsas E, Kumararatne D, Atkinson TP, Schroeder HW Jr, Niehues T, Dückers G, Stray-Pedersen A, Baumann U, Schmidt R, Franco JL, Orrego J, Ben-Shoshan M, McCusker C, Jacob CM, Carneiro-Sampaio M, Devlin LA, Edgar JD, Henderson P, Russell RK, Skytte AB, Seneviratne SL, Wanders J, Stauss H, Meyts I, Moens L, Jesenak M, Kobbe R, Borte S, Borte M, Wright DA, Hagin D, Torgerson TR, Grimbacher B. The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1. J Clin Immunol. 2015 Nov 25. [Epub ahead of print]

McGovern TK, Chen M, Allard B, Larsson K, Martin JG, Adner M. Neutrophilic oxidative stress mediates organic dust-induced pulmonary inflammation and airway hyperresponsiveness. Am J Physiol Lung Cell Mol Physiol. 2015 Nov 6:ajplung.00172.2015. doi: 10.1152/ajplung.00172.2015. [Epub ahead of print]

October 2015

Gros P, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Diagnosis of Obstructive Sleep Apnea in Parkinson’s Disease Patients: Is Unattended Portable Monitoring a Suitable Tool? Parkinsons Dis. 2015;2015:258418. doi: 10.1155/2015/258418. Epub 2015 Oct 13.

Matusovsky OS, Kachmar L, Ijpma G, Bates G, Zitouni N, Benedetti A, Lavoie JP, Lauzon AMPeripheral Airway Smooth Muscle but not the Trachealis is Hypercontractile in an Equine Model of Asthma. Am J Respir Cell Mol Biol. 2015 Oct 16.

Hepple RT, Rice CL. Innervation and neuromuscular control in ageing skeletal muscle. J Physiol. 2015 Oct 6. doi: 10.1113/JP270561.

Flegel K, Martin JGArtificial scents have no place in our hospitals. CMAJ. 2015 Oct 5. pii: cmaj.151097.

Magder SUnderstanding central venous pressure: not a preload index? Curr Opin Crit Care. 2015 Oct;21(5):369-75. doi: 10.1097/MCC.0000000000000238.

September 2015

Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel É, Grimwood K, Hancock RE, Harrison JJ, Heeb S, Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S, Loman N, Malouin F, Manos J, McArthur AG, McKeown J, Milot J, Naghra H, Nguyen D, Pereira SK, Perron GG, Pirnay JP, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Front Microbiol. 2015 Sep 29;6:1036. doi: 10.3389/fmicb.2015.01036.

Laplante P, Fuentes R, Salem D, Subang R, Gillis MA, Hachem A, Farhat N, Qureshi ST, Fletcher CA, Roubey RA, Merhi Y, Thorin É, Levine JS, Mackman N, Rauch J. Antiphospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4. Lupus. 2015 Sep 21. pii: 0961203315603146. [Epub ahead of print]

Venkatesan N, Lavigne P, Lavigne F, Hamid QEffects of Fluticasone Furoate on Clinical and Immunological Outcomes (IL-17) for Patients With Nasal Polyposis Naive to Steroid Treatment. Ann Otol Rhinol Laryngol. 2015 Sep 24. pii: 0003489415606449. [Epub ahead of print]

Sarill M, Zago M, Sheridan JA, Nair P, Matthews J, Gomez A, Roussel L, Rousseau SHamid QEidelman DHBaglole CJ.  The aryl Hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1.  Free Radic Biol Med. 2015 Sep 22. pii: S0891-5849(15)00521-3.

Shourian M, Flaczyk A, Angers I, Mindt BC, Fritz JH, Qureshi STThe Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity. Infect Immun. 2015 Sep 14. pii: IAI.00697-15. [Epub ahead of print]

Marton J, Albert D, Wiltshire SA, Park R, Bergen A, Qureshi S, Malo D, Burelle Y, Vidal SM. Cyclosporine A Treatment Inhibits Abcc6-Dependent Cardiac Necrosis and Calcification following Coxsackievirus B3 Infection in Mice. PLoS One. 2015 Sep 16;10(9):e0138222. doi: 10.1371/journal.pone.0138222.

Kaufman GN, Massoud AH, Dembele M, Yona M, Piccirillo CA, Mazer BDInduction of Regulatory T Cells by Intravenous Immunoglobulin: A Bridge between Adaptive and Innate Immunity. Front Immunol. 2015 Sep 11;6:469. doi: 10.3389/fimmu.2015.00469.

Bonilla FA, Khan DA, Ballas ZK, Mazer B, Nelson RP Jr, Orange JS, Routes JM, Shearer WT, Sorensen RU, Verbsky JW, et al. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol. 2015 Sep 11. pii: S0091-6749(15)00883-0. doi: 10.1016/j.jaci.2015.04.049.

Chekabab SM, Silverman RJ, Lafayette SL, Luo Y, Rousseau S,  Nguyen DStaphylococcus aureus Inhibits IL-8 Responses Induced by Pseudomonas aeruginosa in Airway Epithelial Cells. PLoS One. 2015 Sep 11;10(9):e0137753. doi: 10.1371/journal.pone.0137753.

Bullone M, Beauchamp G, Godbout M, Martin JG, Lavoie JP. Endobronchial Ultrasound Reliably Quantifies Airway Smooth Muscle Remodeling in an Equine Asthma Model. PLoS One. 2015 Sep 8;10(9):e0136284. doi: 10.1371/journal.pone.0136284.

Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Sep 9. pii: 1501105. [Epub ahead of print]

July 2015

LaFayette SL, Houle D, Beaudoin T, Wojewodka G, Radzioch D, Hoffman LR, Burns JL, Dandekar AA, Smalley NE, Chandler JR, Zlosnik JE, Speert DP, Bernier J, Matouk E, Brochiero E, Rousseau SNguyen D.  Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses. Sci Adv. 2015 Jul;1(6). pii: e1500199.

Jeukens J, Freschi L, Kukavica-Ibrulj I, Nguyen D, Levesque RC. Draft Genome Sequence of Triclosan-Resistant Cystic Fibrosis Isolate Achromobacter xylosoxidans CF304. Genome Announc. 2015 Jul 30;3(4). pii: e00865-15. doi: 10.1128/genomeA.00865-15.

Tekwa EW, Nguyen D, Juncker D, Loreau M, Gonzalez A. Patchiness in a microhabitat chip affects evolutionary dynamics of bacterial cooperation. Lab Chip. 2015 Jul 30. [Epub ahead of print]

Novali M, Shalaby KH, Robichaud A, Benedetti A, Fereydoonzad L, McGovern TK, Schuessler TF, Martin JGMechanical consequences of allergic induced remodeling on mice airway resistance and compressibility. Respir Physiol Neurobiol. 2015 Jul 23. pii: S1569-9048(15)30020-3. doi: 10.1016/j.resp.2015.07.007. [Epub ahead of print]

Nguyen D, Nguyen TK, Rice SA, Boyer C. CO-releasing polymers exert antimicrobial activity.Biomacromolecules. 2015 Jul 22. [Epub ahead of print]

Dauletbaev N, Herscovitch K, Das M, Chen H, Bernier J, Matouk E, Bérubé J, Rousseau S, Lands LC. Down-regulation of IL-8 by high-dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up-regulation of DUSP1. Br J Pharmacol. 2015 Jul 14. doi: 10.1111/bph.13249. [Epub ahead of print]

Kimoff RJWhen to Suspect Sleep Apnea and What to Do About It. Can J Cardiol. 2015 Jul;31(7):945-8.

June 2015

Tenkerian C, Krishnamoorthy J, Mounir Z, Kazimierczak U, Khoutorsky A, Staschke KA, Kristof AS, Wang S, Hatzoglou M, Koromilas AE. mTORC2 balances Akt activation and eIF2alpha serine 51 phosphorylation to promote survival under stress. Mol Cancer Res. 2015 Jun 30.

Urb M, Snarr BD, Wojewodka G, Lehoux M, Lee MJ, Ralph B, Divangahi M, King IL, McGovern TK, Martin JG, Fraser R, Radzioch D, Sheppard DC. The evolution of the immune response to chronic airway colonization with Aspergillus fumigatus hyphae. Infect Immun. 2015 Jun 29. pii: IAI.00359-15. [Epub ahead of print]

Divangahi MEfferocytosis: Burying cell corpses to regulate tolerance and immunity.Oncotarget. 2015 Jun 20;6(17):14721-2.

Ahlgren HG, Benedetti A, Landry JS, Bernier J, Matouk E, Radzioch D, Lands LC, Rousseau S, Nguyen DClinical outcomes associated with Staphylococcus aureus and Pseudomonas aeruginosa airway infections in adult cystic fibrosis patients. BMC Pulm Med. 2015 Jun 21;15:67

Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, et al. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadCarcinogenesis. 2015 Jun;36 Suppl 1:S254-96. doi: 10.1093/carcin/bgv039.

Jaberi A, Hooker E, Guillemette J, Papillon J, Kristof AS, Cybulsky AV. Identification of Tpr and α-Actinin-4 as Two Novel SLK-Interacting Proteins. Biochim Biophys Acta. 2015 Jun 18. pii: S0167-4889(15)00195-0. doi: 10.1016/j.bbamcr.2015.06.005. [Epub ahead of print]

Nishioka M, Venkatesan N, Dessalle K, Mogas A, Kyoh S, Lin TY, Nair P, Baglole CJ, Eidelman DH, Ludwig MS, Hamid QFibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respir Res. 2015 Jun 18;16:72

Gros P, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Obstructive sleep apnea in Parkinson’s disease patients: effect of Sinemet CR taken at bedtime. Sleep Breath. 2015 Jun 13. [Epub ahead of print]

Neufer PD, Bamman MM, Muoio DM, Bouchard C, Cooper DM, Goodpaster BH, Booth FW, Kohrt WM, Gerszten RE, Mattson MP, Hepple RT, Kraus WE, Reid MB, Bodine SC, Jakicic JM, Fleg JL, Williams JP, Joseph L, Evans M, Maruvada P, Rodgers M, Roary M, Boyce AT, Drugan JK, Koenig JI, Ingraham RH, Krotoski D, Garcia-Cazarin M, McGowan JA, Laughlin MR. Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits.Cell Metab. 2015 Jun 9. pii: S1550-4131(15)00223-5. doi: 10.1016/j.cmet.2015.05.011. [Epub ahead of print] Review.

Thompson PA, Khatami M, Baglole CJ, Sun J, Harris S, Moon EY, Al-Mulla F, Al-Temaimi R, Brown D, Colacci A, Mondello C, Raju J, Ryan E, Woodrick J, Scovassi I, Singh N, Vaccari M, Roy R, Forte S, Memeo L, Salem HK, Amedei A, Hamid RA, Lowe L, Guarnieri T, Bisson WH. Environmental immune disruptors, inflammation and cancer risk. Carcinogenesis. 2015 Jun;36 Suppl 1:S232-53

May 2015

Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WSBiosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochem Pharmacol. 2015 Aug 1;96(3):247-55.

Bandara HM, Nguyen D, Mogarala S, Osiñski M, Smyth HD. Magnetic fields suppress Pseudomonas aeruginosa biofilms and enhance ciprofloxacin activity. Biofouling. 2015 May;31(5):443-57

McClung JM, Reinardy JL, Mueller SB, McCord TJ, Kontos CD, Brown DA, Hussain SN, Schmidt CA, Ryan TE, Green TD. Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment. Front Physiol. 2015 May 19;6:161

Giordano C, Lemaire C, Li T, Kimoff RJPetrof BJAutophagy-Associated Atrophy and Metabolic Remodeling of the Mouse Diaphragm after Short-Term Intermittent Hypoxia. PLoS One. 2015 Jun 24;10(6):e0131068

Sheridan JA, Zago M, Nair P, Li PZ, Bourbeau J, Tan WC, Hamid QEidelman DH, Benedetti AL, Baglole CJDecreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression. Respir Res. 2015 May 6;16(1):54. doi: 10.1186/s12931-015-0214-6.

Al Heialy S, Zeroual M, Farahnak S, McGovern T, Risse PA, Novali M,Lauzon AM, Roman HN, Martin JGNanotubes Connect CD4+ T Cells to Airway Smooth Muscle Cells: Novel Mechanism of T Cell Survival. J Immunol. 2015 May 1. pii: 1401718. [Epub ahead of print]

April 2015

Mery V, Kimoff RJ, Suarez I, Benedetti A, Kaminska M, Robinson A, Lapierre Y, Bar-Or A, Trojan DA. High false-positive rate of questionnaire-based restless legs syndrome diagnosis in multiple sclerosis. Sleep Med. 2015 Mar 6. pii: S1389-9457(15)00641-3. doi: 10.1016/j.sleep.2015.02.529. [Epub ahead of print]

Navarro LH, Bloomstone JA, Auler JO Jr, Cannesson M, Rocca GD, Gan TJ, Kinsky M, Magder S, Miller TE, Mythen M, Perel A, Reuter DA, Pinsky MR, Kramer GC. Perioperative fluid therapy: a statement from the international Fluid Optimization Group. Perioper Med (Lond). 2015 Apr 10;4:3. doi: 10.1186/s13741-015-0014-z. eCollection 2015.

Paun A, Kunwar A, Haston CKAcute adaptive immune response correlates with late radiation-induced pulmonary fibrosis in mice. Radiat Oncol. 2015 Feb 20;10(1):45.

Kaminska M, Browman F, Trojan DA, Genge A, Benedetti A,Petrof BJFeasibility of lung volume recruitment in early neuromuscular weakness: a comparison between amyotrophic lateral sclerosis, myotonic dystrophy and post-polio syndrome. PM R. 2015 Apr 3. pii: S1934-1482(15)00178-1. doi: 10.1016/j.pmrj.2015.04.001

Divangahi M, King IL, Pernet E. Alveolar macrophages and type I IFN in airway homeostasis and immunity. Trends Immunol. 2015 Apr 2. pii: S1471-4906(15)00052-6. doi: 10.1016/j.it.2015.03.005

Azuelos I, Jung B, Picard M, Liang F, Li T, Lemaire C, Giordano C, Hussain S, Petrof BJRelationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction. Anesthesiology. 2015 Mar 31. [Epub ahead of print]

Echavarria R, Mayaki D, Neel JC, Harel S, Sanchez V, Hussain SNAngiopoietin-1 inhibits Toll-like receptor 4 signaling in cultured endothelial cells: Role of miR-146b-5p.
Cardiovasc Res. 2015 Mar 30

March 2015

Magder S, Parthenis DG, Ghouleh IA. Preservation of Renal Blood Flow by the Antioxidant EUK-134 in LPS-Treated Pigs. Int J Mol Sci. 2015 Mar 25;16(4):6801-17. doi: 10.3390/ijms16046801.

Tiedje C, Lubas M, Tehrani M, Menon MB, Ronkina N, Rousseau S, Cohen P, Kotlyarov A, Gaestel M. p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex. RNA. 2015 Feb;21(2):262-78. doi: 10.1261/rna.048090.114. Epub 2014 Dec 18.

Trinh NT, Bilodeau C, Maillé É, Ruffin M, Quintal MC, Desrosiers MY, Rousseau S, Brochiero E. Deleterious impact of Pseudomonas aeruginosa on cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells. Eur Respir J. 2015 Mar 18. pii: ERJ-00762-2014. [Epub ahead of print]

Kristof AS, Li PZ, Major P, Landry JS. Lymphangioleiomyomatosis and Tuberous Sclerosis Complex in Quebec: Prevalence and Health Care Utilization. Chest. 2015 Mar 19. doi: 10.1378/chest.14-3095. [Epub ahead of print]

Michael H, Li Y, Wang Y, Xue D, Shan J, Mazer BD, McCusker CTTGF-β-mediated airway tolerance to allergens induced by peptide-based immunomodulatory mucosal vaccination. Mucosal Immunol. 2015 Mar 18. doi: 10.1038/mi.2015.15. [Epub ahead of print]

Paun A, Kunwar A, Haston CKAcute adaptive immune response correlates with late radiation-induced pulmonary fibrosis in mice. Radiat Oncol. 2015 Dec;10(1):359. doi: 10.1186/s13014-015-0359-y. Epub 2015 Feb 20.

Picard M, Azuelos I, Jung B, Giordano C, Matecki S, Hussain SN, White K, Li T, Liang F, Benedetti A, Gentil BJ, Burelle Y, Petrof BJMechanical Ventilation Triggers Abnormal Mitochondrial Dynamics and Morphology in the Diaphragm. J Appl Physiol (1985). 2015 Mar 12:jap.00873.2014. doi: 10.1152/japplphysiol.00873.2014. [Epub ahead of print]

Gore V, Chourey S, Ye Q, Patel P, Ouedraogo Y, Gravel S, Powell WS, Rokach J. Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3385-8. doi: 10.1016/j.bmcl.2014.05.090. Epub 2014 Jun 4

Gouspillou G, Scheede-Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, Archer-Lahlou E, Sgarioto N, Purves-Smith FM, Konokhova Y, Rak J, Chevalier S, Taivassalo T, Hepple RT, Jagoe RT. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep. 2015 Mar 3;5:8717. doi: 10.1038/srep08717.

February 2015

Lajoie S, Lewkowich I, Herman NS, Sproles A, Pesce JT, Wynn TA, Grusby MJ, Hamid Q, Wills-Karp MIL-21 Receptor Signaling Partially Mediates Th2-Mediated Allergic Airway Responses. Clin Exp Allergy. 2014 Jul;44(7):976-85. doi: 10.1111/cea.12341.

Magder S, Verscheure S. Proper reading of pulmonary artery vascular pressure tracings.Am J Respir Crit Care Med. 2014 Nov 15;190(10):1196-8. doi: 10.1164/rccm.201408-1526LE. No abstract available.

Bazett M, Honeyman L, Stefanov AN, Pope CE, Hoffman LR, Haston CK. Cystic fibrosis mouse model-dependent intestinal structure and gut microbiome. Mamm Genome. 2015 Feb 27. [Epub ahead of print]

Borges MC, Narayanan V, Ludwig MS. Deficiency of decorin induces expression of Foxp3 in CD4+CD25+ T cells in a murine model of allergic asthma. Respirology. 2015 Feb 25. doi: 10.1111/resp.12485. [Epub ahead of print]

Ijpma G, Kachmar L, Matusovsky OS, Bates JH, Benedetti A, Martin JGLauzon AMHuman Trachealis and Main Bronchi Smooth Muscle Are Normo-Responsive in Asthma. Am J Respir Crit Care Med. 2015 Feb 19. [Epub ahead of print]

Kaminska M, Trojan DA, Kimoff RJ. Association between OSA and Severe Fatigue in Patients with Multiple Sclerosis (MS). J Clin Sleep Med. 2014 Jun 15;10(6):707. doi: 10.5664/jcsm.3818. No abstract available.

Rico de Souza A, Zago M, Eidelman DHHamid QBaglole CJ. Aryl Hydrocarbon Receptor (AhR) Attenuation of Sub-Chronic Cigarette Smoke-Induced Pulmonary Neutrophilia is Associated with Retention of Nuclear RelB and Suppression of Intercellular Adhesion Molecule-1 (ICAM-1). Toxicol Sci. 2014 Jul;140(1):204-23. doi: 10.1093/toxsci/kfu068. Epub 2014 Apr 20.

McGarvey L, Niewoehner D, Magder S, Sachs P, Tetzlaff K, Hamilton A, Korducki L, Bothner U, Vogelmeier C, Koch A, Ferguson GT. One-Year Safety of Olodaterol Once Daily via Respimat® in Patients with GOLD 2-4 Chronic Obstructive Pulmonary Disease: Results of a Pre-Specified Pooled Analysis. COPD. 2015 Feb 18. [Epub ahead of print]

Lafferty EI, Wiltshire SA, Angers I, Vidal SM, Qureshi STUnc93b1 -Dependent Endosomal Toll-Like Receptor Signaling Regulates Inflammation and Mortality during Coxsackievirus B3 Infection.J Innate Immun. 2015 Feb 11. [Epub ahead of print]

Bazett M, Haston CKAirway hyperresponsiveness in FVB/N delta F508 cystic fibrosis transmembrane conductance regulator mice. J Cyst Fibros. 2014 Jul;13(4):378-83. doi: 10.1016/j.jcf.2013.11.010. Epub 2013 Dec 24.

Massoud AH, Kaufman GN, Piccirillo CA, Mazer BDReply. J Allergy Clin Immunol. 2014 Dec;134(6):1469-70. doi: 10.1016/j.jaci.2014.08.050. Epub 2014 Oct 28. No abstract available.

Hilbert L, Balassy Z, Zitouni NB, Mackey MC,  Lauzon AM. Phosphate and ADP Differently Inhibit Coordinated Smooth Muscle Myosin Groups. Biophys J. 2015 Feb 3;108(3):622-631. doi: 10.1016/j.bpj.2014.12.008.

January 2015

Roman HN, Juncker D, Lauzon AMA microfluidic chamber to study the dynamics of muscle contraction specific molecular interactions. Anal Chem. 2015 Jan 28. [Epub ahead of print]

Hecht E, Zago M, Sarill M, Rico de Souza A, Gomez A, Matthews J, Hamid QEidelman DHBaglole CJAryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation. Toxicol Appl Pharmacol. 2014 Nov 1;280(3):511-25. doi: 10.1016/j.taap.2014.08.023. Epub 2014 Aug 30.

Maes K, Stamiris A, Thomas D, Cielen N, Smuder A, Powers SK, Leite FS, Hermans G, Decramer M, Hussain SN, Gayan-Ramirez G. Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats. Crit Care Med. 2014 Dec;42(12):e772-82. doi: 10.1097/CCM.0000000000000685.

Mofarrahi M, McClung JM, Kontos CD, Davis EC, Tappuni B, Moroz N, Pickett AE, Huck L, Harel S, Danialou G, Hussain SNANGIOPOIETIN-1 ENHANCES SKELETAL MUSCLE REGENERATION IN MICE. Am J Physiol Regul Integr Comp Physiol. 2015 Jan 21:ajpregu.00267.2014. doi: 10.1152/ajpregu.00267.2014. [Epub ahead of print]

Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG. The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo. Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2.

Scadding GK, Brock C, Chouiali F, Hamid QLaryngeal Inflammation In The Sudden Infant Death Syndrome. Curr Pediatr Rev. 2015 Jan 16. [Epub ahead of print]

Boivin R, Vargas A, Lefebvre-Lavoie J, Lauzon AM, Lavoie JP. Inhaled corticosteroids modulate the (+)insert smooth muscle myosin heavy chain in the equine asthmatic airways. Thorax. 2014 Dec;69(12):1113-9. doi: 10.1136/thoraxjnl-2014-205572. Epub 2014 Sep 9.

Hirota N, McCuaig S, O’Sullivan MJ, Martin JG. Serotonin augments smooth muscle differentiation of bone marrow stromal cells. Stem Cell Res. 2014 May;12(3):599-609. doi: 10.1016/j.scr.2014.02.003. Epub 2014 Feb 13.

Wojewodka G, De Sanctis JB, Bernier J, Bérubé J, Ahlgren HG, Gruber J, Landry J, Lands LC, Nguyen D, Rousseau S, Benedetti A, Matouk E, Radzioch D. Candidate Markers Associated with the Probability of Future Pulmonary Exacerbations in Cystic Fibrosis Patients. PLoS One. 2014 Feb 12;9(2):e88567. eCollection 2014.

December 2014

Tzelepis F, Verway M, Daoud J, Gillard J, Hassani-Ardakani K, Dunn J, Downey J, Gentile ME, Jaworska J, Sanchez AM, Nédélec Y, Vali H, Tabrizian M, Kristof AS, King IL, Barreiro LB, Divangahi MAnnexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection. J Clin Invest. 2014 Dec 22. pii: 77014. doi: 10.1172/JCI77014. [Epub ahead of print]

Giordano C, Mojumdar K, Liang F, Lemaire C, Li T, Richardson J, Divangahi M, Qureshi S, Petrof BJToll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy. Hum Mol Genet. 2014 Dec 30. pii: ddu735. [Epub ahead of print]

Kunwar A, Haston CK. DNA damage at respiratory distress, but not acute time points, correlates with tissue fibrosis following thoracic radiation exposure in mice. Int J Radiat Biol. 2014 Dec 20:1-24. [Epub ahead of print]

Kunwar A, Haston CK. Basal levels of glutathione peroxidase correlate with onset of radiation induced lung disease in inbred mouse strains. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 15;307(8):L597-604. doi: 10.1152/ajplung.00088.2014. Epub 2014 Aug 22.

Magder S, Emami A. Practical Approach to Physical-Chemical Acid-Base Management: Stewart at the Bedside. Ann Am Thorac Soc. 2014 Dec 15. [Epub ahead of print]

Mofarrahi M, Guo Y, Haspel JA, Choi AM, Davis EC, Gouspillou G, Hepple RT, Godin R, Burelle Y, Hussain SN. Autophagic flux and oxidative capacity of skeletal muscles during acute starvation.Autophagy. 2013 Oct;9(10):1604-20. doi: 10.4161/auto.25955. Epub 2013 Aug 15.

Povitz M, Kimoff RJUse of a level 3 portable monitor for the diagnosis and management of sleep disordered breathing in an inpatient tertiary care setting. Can Respir J. 2014 Mar-Apr;21(2):96-100. Epub 2013 Nov 28.

Halwani R, Al-Kufaidy R, Vazquez-Tello A, Pureza MA, BaHammam AS, Al-Jahdali H, Alnassar SA, Hamid Q, Al-Muhsen S. IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma. PLoS One. 2014 Dec 10;9(12):e114604. doi: 10.1371/journal.pone.0114604. eCollection 2014.

Behr MA, Divangahi MFreund’s adjuvant, NOD2 and mycobacteria. Curr Opin Microbiol. 2014 Dec 4;23C:126-132. doi: 10.1016/j.mib.2014.11.015. [Epub ahead of print] Review.

Powell WS, Rokach J. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid. Biochim Biophys Acta. 2014 Oct 29. pii: S1388-1981(14)00217-0. doi: 10.1016/j.bbalip.2014.10.008. [Epub ahead of print] Review.

Massoud AH, Kaufman GN, Piccirillo CA, Mazer BD. Reply. J Allergy Clin Immunol. 2014 Oct 28;134(6):1469-1470. doi: 10.1016/j.jaci.2014.08.050. [Epub ahead of print] No abstract available.

Magder S. Invasive Hemodynamic Monitoring. Crit Care Clin. 2015 Jan;31(1):67-87. doi: 10.1016/j.ccc.2014.08.004. Review.

November 2014

Chang Y, Al-Alwan L, Alshakfa S, Audusseau S, Mogas A, Chouiali F, Nair P, Baglole CJHamid Q,Eidelman DHUpregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD. Respir Res. 2014 Nov 27;15(1):145. [Epub ahead of print]

Labonté L, Coulombe P, Zago M, Bourbeau J, Baglole CJAlterations in the Expression of the NF-κB Family Member RelB as a Novel Marker of Cardiovascular Outcomes during Acute Exacerbations of Chronic Obstructive Pulmonary Disease. PLoS One. 2014 Nov 19;9(11):e112965. doi: 10.1371/journal.pone.0112965. eCollection 2014.

Srinivasa BT, Fixman ED, Ward BJ. Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease. Eur J Immunol. 2014 Aug;44(8):2349-59. doi: 10.1002/eji.201344206. Epub 2014 Jun 5.

Maes K, Stamiris A, Thomas D, Cielen N, Smuder A, Powers SK, Leite FS, Hermans G, Decramer M, Hussain SN, Gayan-Ramirez G. Effects of Controlled Mechanical Ventilation on Sepsis-Induced Diaphragm Dysfunction in Rats. Crit Care Med. 2014 Dec;42(12):e772-e782

Magder S, Verscheure S. Proper Reading of Pulmonary Artery Vascular Pressure Tracings.Am J Respir Crit Care Med. 2014 Nov 15;190(10):1196-1198. No abstract available.

Risse PA, Lavoie-Lamoureux A, Jo T, Tsuchiya K, Siddiqui S, Martin JG. Airway arginase expression and Nω-hydroxy-nor-Arginine effect on methacholine-induced bronchoconstriction differentiate Lewis and Fischer rat strains. J Appl Physiol (1985). 2014 Mar 15;116(6):621-7. doi: 10.1152/japplphysiol.01241.2013. Epub 2014 Feb 6.

October 2014

Bener A, Ehlayel MS, Bener HZ, Hamid QThe impact of Vitamin D deficiency on asthma, allergic rhinitis and wheezing in children: An emerging public health problem. J Family Community Med. 2014 Sep;21(3):154-61. doi: 10.4103/2230-8229.142967.

Betschel S, Badiou J, Binkley K, Hébert J, Kanani A, Keith P, Lacuesta G, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Longhurst H, Zuraw B, Boysen H, Borici-Mazi R, Bowen T, Dallas K, Dean J, Lang-Robertson K, Laramée B, Leith E, Mace S, McCusker C, Moote B, Poon MC, Ritchie B, Stark D, Sussman G, Waserman S. Canadian hereditary angioedema guideline. Allergy Asthma Clin Immunol. 2014 Oct 24;10(1):50. doi: 10.1186/1710-1492-10-50. eCollection 2014.

Lavoie-Lamoureux A, Martin JG, Lavoie JP. Characterization of arginase expression by equine neutrophils. Vet Immunol Immunopathol. 2014 Feb 15;157(3-4):206-13. doi: 10.1016/j.vetimm.2013.12.007. Epub 2013 Dec 30.

Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, Adcock IM, Bateman ED, Bel EH, Bleecker ER, Boulet LP, Brightling C, Chanez P, Dahlen SE, Djukanovic R, Frey U, Gaga M, Gibson P, Hamid Q, Jajour NN, Mauad T, Sorkness RL, Teague WG. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J. 2014 Feb;43(2):343-73. doi: 10.1183/09031936.00202013. Epub 2013 Dec 12. Erratum in: Eur Respir J. 2014 Apr;43(4):1216. Dosage error in article text

Arron JR, Choy DF, Laviolette M, Kelsen SG, Hatab A, Leigh R, Thomson NC, Bleecker ER, Olivenstein R, Avila PC, Jarjour NN, Castro M, Gauvreau GM, Good JT, Kline JN, Mansur A, Mayers I, Heaney LG, Hamid Q, Harris JM. Disconnect between sputum neutrophils and other measures of airway inflammation in asthma. Eur Respir J. 2014 Feb;43(2):627-9. doi: 10.1183/09031936.00117013. Epub 2013 Oct 31. No abstract available.

Mojumdar K, Liang F, Giordano C, Lemaire C, Danialou G, Okazaki T, Bourdon J, Rafei M, Galipeau J, Divangahi MPetrof BJInflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2. EMBO Mol Med. 2014 Oct 13. pii: e201403967. doi: 10.15252/emmm.201403967. [Epub ahead of print]

Purves-Smith FM, Sgarioto N, Hepple RTFiber typing in aging muscle. Exerc Sport Sci Rev. 2014 Apr;42(2):45-52. doi: 10.1249/JES.0000000000000012. Review.

Hepple RTMitochondrial involvement and impact in aging skeletal muscle. Front Aging Neurosci. 2014 Sep 10;6:211. doi: 10.3389/fnagi.2014.00211. eCollection 2014. Review.

Tang H, Smith IJ, Hussain SNGoldberg P, Lee M, Sugiarto S, Godinez GL, Singh BK, Payan DG, Rando TA, Kinsella TM, Shrager JB. The JAK-STAT Pathway is Critical in Ventilator-induced Diaphragm Dysfunction. Mol Med. 2014 Sep 30. doi: 10.2119/molmed.2014.00049. [Epub ahead of print]

September 2014

Coulombe F, Divangahi MTargeting eicosanoid pathways in the development of novel anti-influenza drugs. Expert Rev Anti Infect Ther. 2014 Sep 30:1-7. [Epub ahead of print]

Lin TY, Venkatesan N, Nishioka M, Kyoh S, Al-Alwan L, Baglole CJEidelman DHLudwig MSHamid QMonocyte-derived fibrocytes induce an inflammatory phenotype in airway smooth muscle cells. Clin Exp Allergy. 2014 Sep 25. doi: 10.1111/cea.12421. [Epub ahead of print]

Al-Alwan LA, Chang Y, Rousseau SMartin JGEidelman DHHamid QCXCL1 Inhibits Airway Smooth Muscle Cell Migration through the Decoy Receptor Duffy Antigen Receptor for Chemokines. J Immunol. 2014 Aug 1;193(3):1416-26. doi: 10.4049/jimmunol.1302860. Epub 2014 Jun 30.

Magder SBalanced versus unbalanced salt solutions: What difference does it make? Best Pract Res Clin Anaesthesiol. 2014 Sep;28(3):235-247. doi: 10.1016/j.bpa.2014.07.001. Epub 2014 Jul 18. Review.

McGovern TK, Goldberger M, Allard B, Farahnak S, Hamamoto Y, O’Sullivan M, Hirota N, Martel G, Rousseau S, Martin JGNeutrophils Mediate Airway Hyperresponsiveness Following Chlorine-Induced Airway Injury in the Mouse. Am J Respir Cell Mol Biol. 2014 Sep 5. [Epub ahead of print]

August 2014

Yáñez A, Cho SH, Soriano JB, Rosenwasser LJ, Rodrigo GJ, Rabe KF, Peters S, Niimi A, Ledford DK, Katial R, Hoyte FC, Fabbri LM, Celedón JC, Canonica GW, Busse P, Boulet LP, Baena-Cagnani CE, Hamid Q, Bachert C, Pawankar R, Holgate ST. Asthma in the elderly: what we know and what we have yet to knowWorld Allergy Organ J. 2014 May 30;7(1):8. doi: 10.1186/1939-4551-7-8. eCollection 2014. Review.

July 2014

Nakada EM, Shan J, Kinyanjui MW, Fixman ED. Adjuvant-dependent regulation of interleukin-17 expressing ¿¿ T cells and inhibition of Th2 responses in allergic airways disease. Respir Res. 2014 Aug 14;15(1):90. [Epub ahead of print]

Gouspillou G, Sgarioto N, Norris B, Barbat-Artigas S, Aubertin-Leheudre M, Morais JA, Burelle Y, Taivassalo T,  Hepple RTThe Relationship between Muscle Fiber Type-Specific PGC-1α Content and Mitochondrial Content Varies between Rodent Models and Humans. PLoS One. 2014 Aug 14;9(8):e103044. doi: 10.1371/journal.pone.0103044. eCollection 2014.

Roman HN, Zitouni NB, Kachmar L, Benedetti A, Sobieszek A, Lauzon AM. The role of caldesmon and its phosphorylation by ERK on the binding force of unphosphorylated myosin to actin.Biochim Biophys Acta. 2014 Aug 7. pii: S0304-4165(14)00269-4. doi: 10.1016/j.bbagen.2014.07.024. [Epub ahead of print]

Bullone M, Chevigny M, Allano M, Martin JG, Lavoie JP. Technical and physiological determinants of airway smooth muscle mass in endobronchial biopsy samples of asthmatic horses. J Appl Physiol (1985). 2014 Aug 7. pii: jap.00468.2014. [Epub ahead of print]

Zago M, Sheridan JA, Nair P, Rico de Souza A, Gallouzi IE, Rousseau S, Di Marco S, Hamid Q, Eidelman DHBaglole CJ. Aryl Hydrocarbon Receptor-Dependent Retention of Nuclear HuR Suppresses Cigarette Smoke-Induced Cyclooxygenase-2 Expression Independent of DNA-Binding. PLoS One. 2013 Sep 27;8(9):e74953. doi: 10.1371/journal.pone.0074953. eCollection 2013.

Chow SC, Gowing SD, Cools-Lartigue JJ, Chen CB, Berube J, Yoon HW, Chan CH, Rousseau MC, Bourdeau F, Giannias B, Roussel L, Qureshi STRousseau S, Ferri LE. Gram Negative Bacteria Increase Non-Small Cell Lung Cancer Metastasis Via Toll-Like Receptor 4 Activation and Mitogen-Activated Protein Kinase Phosphorylation. Int J Cancer. 2014 Aug 1. doi: 10.1002/ijc.29111. [Epub ahead of print]

Patel P, Reddy CN, Gore V, Chourey S, Ye Q, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Two Potent OXE-R Antagonists: Assignment of Stereochemistry. ACS Med Chem Lett. 2014 May 29;5(7):815-9. doi: 10.1021/ml500161v. eCollection 2014 Jul 10.

Jaworska J, Coulombe F, Downey J, Tzelepis F, Shalaby K, Tattoli I, Berube J, Rousseau SMartin JG, Girardin SE, McCullers JA, Divangahi MNLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2110-9. doi: 10.1073/pnas.1322118111. Epub 2014 May 5.

Coulombe F, Jaworska J, Verway M, Tzelepis F, Massoud A, Gillard J, Wong G, Kobinger G, Xing Z, Couture C, Joubert P, Fritz JH, Powell WSDivangahi MTargeted Prostaglandin E<sub>2</sub> Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages. Immunity. 2014 Apr 17;40(4):554-68. doi: 10.1016/j.immuni.2014.02.013. Epub 2014 Apr 10.

Johnson JR, Nishioka M, Chakir J, Risse PA, Almaghlouth I, Bazarbashi AN, Plante S, Martin JGEidelman DHamid QIL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res. 2013 Nov 1;14(1):118.

June 2014

Mac Sharry J, Shalaby KH, Marchica C, Farahnak S, Chieh-Li T, Lapthorne S, Qureshi ST, Shanahan F, Martin JG. Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of AsthmaPLoS One. 2014 Jun 26;9(6):e98648. doi: 10.1371/journal.pone.0098648. eCollection 2014.

Paun A, Bergeron ME, Haston CK. NKT Deficient Mice are not Spared Lung Disease after Exposure to Thoracic Radiotherapy. Radiat Res. 2014 Apr;181(4):369-75. doi: 10.1667/RR13581.1. Epub 2014 Apr 4.

Powell WS, Rokach J. The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor. Prog Lipid Res. 2013 Oct;52(4):651-65. doi: 10.1016/j.plipres.2013.09.001. Epub 2013 Sep 19. Review.

Piquereau J, Godin R, Deschênes S, Bessi VL, Mofarrahi M, Hussain SN, Burelle Y. Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction.Autophagy. 2013 Nov 1;9(11):1837-51. doi: 10.4161/auto.26502. Epub 2013 Oct 3.

Okazaki T, Liang F, Li T, Lemaire C, Danialou G, Shoelson SE, Petrof BJ. Muscle-Specific Inhibition of the Classical Nuclear Factor-κB Pathway Is Protective Against Diaphragmatic Weakness in Murine Endotoxemia. Crit Care Med. 2014 Jul;42(7):e501-e509.

Magder SAReply: reply: prone positioning actually exerts benefits on hemodynamics!. Am J Respir Crit Care Med. 2014 Jun 15;189(12):1568-9. doi: 10.1164/rccm.201404-0725LE. No abstract available.

Echavarria R, Hussain SNRegulation of angiopoietin-1/tie-2 receptor signaling in endothelial cells by dual-specificity phosphatases 1, 4, and 5. J Am Heart Assoc. 2013 Dec 5;2(6):e000571. doi: 10.1161/JAHA.113.000571.

Hilbert L, Bates G, Roman HN, Blumenthal JL, Zitouni NB, Sobieszek A, Mackey MC, Lauzon AM. Molecular Mechanical Differences between Isoforms of Contractile Actin in the Presence of Isoforms of Smooth Muscle Tropomyosin. PLoS Comput Biol. 2013 Oct;9(10):e1003273. doi: 10.1371/journal.pcbi.1003273. Epub 2013 Oct 24.

Magder SAThe highs and lows of blood pressure: toward meaningful clinical targets in patients with shock. Crit Care Med. 2014 May;42(5):1241-51. doi: 10.1097/CCM.0000000000000324. Review.

McGovern TK, Robichaud A, Fereydoonzad L, Schuessler TF, Martin JGEvaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique. J Vis Exp. 2013 May 15;(75). doi: 10.3791/50172.

Gouspillou G, Sgarioto N, Kapchinsky S, Purves-Smith F, Norris B, Pion CH, Barbat-Artigas S, Lemieux F, Taivassalo T, Morais JA, Aubertin-Leheudre M, Hepple RT. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 2014 Apr;28(4):1621-33. doi: 10.1096/fj.13-242750. Epub 2013 Dec 26.

Desjardins M, Mazer BDB-cell memory and primary immune deficiencies: interleukin-21 related defects. Curr Opin Allergy Clin Immunol. 2013 Dec;13(6):639-45. doi: 10.1097/ACI.0000000000000009. Review.

Lee N, Qureshi STOther viral pneumonias: coronavirus, respiratory syncytial virus, adenovirus, hantavirus. Crit Care Clin. 2013 Oct;29(4):1045-68. doi: 10.1016/j.ccc.2013.07.003. Epub 2013 Aug 9. Review.

May 2014

Lafferty EI, Flaczyk A, Angers I, Homer R, d’Hennezel E, Malo D, Piccirillo CA, Vidal SM, Qureshi ST. An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection. Genes Immun. 2014 May 22. doi: 10.1038/gene.2014.22. [Epub ahead of print]

Zago M, Souza AR, Hecht E, Rousseau SHamid QEidelman DHBaglole CJ. The NF-κB family member RelB regulates microRNA miR-146a to suppress cigarette smoke-induced COX-2 protein expression in lung fibroblasts. Toxicol Lett. 2014 Apr 21;226(2):107-16. doi: 10.1016/j.toxlet.2014.01.020. Epub 2014 Jan 25.

Poon AH, Mahboob B, Hamid Q. Vitamin D deficiency and severe asthma. Pharmacol Ther. 2013 Nov;140(2):148-55. doi: 10.1016/j.pharmthera.2013.06.006. Epub 2013 Jun 18. Review.

Lavigne F, Petrof BJ, Johnson JR, Lavigne P, Binothman N, Kassissia GO, Al Samri M, Giordano C, Dubé N, Hercz D, Benedetti A, Hamid QEffect of topical corticosteroids on allergic airway inflammation and disease severity in obstructive sleep apnoea. Clin Exp Allergy. 2013 Oct;43(10):1124-33. doi: 10.1111/cea.12158.

Srinivasa BT, Fixman ED, Ward BJ. Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease. Eur J Immunol. 2014 May 5. doi: 10.1002/eji.201344206. [Epub ahead of print]

Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MV, Schlesinger LS, Divangahi M, Reed MB, Behr MA. N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis. J Infect Dis. 2014 Apr 1;209(7):1045-54. doi: 10.1093/infdis/jit622. Epub 2013 Nov 21.

Nadigel J, Audusseau S, Baglole CJ, Eidelman DHHamid Q. IL-8 production in response to cigarette smoke is decreased in epithelial cells from COPD patients. Pulm Pharmacol Ther. 2013 Oct;26(5):596-602. doi: 10.1016/j.pupt.2013.03.002. Epub 2013 Mar 15.

Borges MC, Marchica CL, Narayanan V, Ludwig MS. Allergen challenge during halothane compared to isoflurane anesthesia induces a more potent peripheral lung response. Respir Physiol Neurobiol. 2013 Oct 1;189(1):144-52. doi: 10.1016/j.resp.2013.07.005. Epub 2013 Jul 20.

Massoud AH, Yona M, Xue D, Chouiali F, Alturaihi H, Ablona A, Mourad W, Piccirillo CA, Mazer BD. Dendritic cell immunoreceptor: A novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells. J Allergy Clin Immunol. 2014 Mar;133(3):853-63.e5. doi: 10.1016/j.jaci.2013.09.029. Epub 2013 Nov 8.

Polverino F, Santoriello C, Andò F, Girbino G, Cappetta D, D’Agostino B, Vatrella A, Polverino M, Milic-Emili JRecumbent deoxygenation in mild/moderate liver cirrhosis: the “Clinodeoxia”. The ortho-clino paradigm. Respir Med. 2014 Apr 15. pii: S0954-6111(14)00128-0. doi: 10.1016/j.rmed.2014.04.003. [Epub ahead of print]

Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigaré R, Dekhuijzen PN, Franssen F, Gayan-Ramirez G, Gea J, Gosker HR, Gosselink R, Hayot M, Hussain SN, Janssens W, Polkey MI, Roca J, Saey D, Schols AM, Spruit MA, Steiner M, Taivassalo T, Troosters T, Vogiatzis I, Wagner PD; on behalf of the ATS/ERS Ad Hoc Committee on Limb Muscle Dysfunction in COPD. An Official American Thoracic Society/European Respiratory Society Statement: Update on Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2014 May 1;189(9):e15-e62.

April 2014

Venkatesan N, Tsuchiya K, Kolb M, Farkas L, Bourhim M, Ouzzine M, Ludwig MSGlycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-β1-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2014 Mar;50(3):583-94. doi: 10.1165/rcmb.2012-0226OC.

Magder S. Current tools for assessing heart function and perfusion adequacy. Curr Opin Crit Care. 2014 Apr 21. [Epub ahead of print]

Lin TY, Venkatesan N, Mahboub B, Hamid QInvolvement of lymphocytes in asthma and allergic diseases: a genetic point of view. Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):500-6. doi: 10.1097/ACI.0b013e328364ea3a. Review.

Bissonnette EY, Madore AM, Chakir J, Laviolette M, Boulet LP, Hamid Q, Bergeron C, Maghni K, Laprise C.Fibroblast growth factor-2 is a sputum remodeling biomarker of severe asthma.J Asthma. 2014 Mar;51(2):119-26. doi: 10.3109/02770903.2013.860164. Epub 2013 Nov 25.

O’Sullivan MJ, Hirota N, Martin JG. Sphingosine 1-Phosphate (S1P) Induced Interleukin-8 (IL-8) Release Is Mediated by S1P Receptor 2 and Nuclear Factor κB in BEAS-2B Cells. PLoS One. 2014 Apr 17;9(4):e95566. doi: 10.1371/journal.pone.0095566. eCollection 2014.

Magder SA. The highs and lows of blood pressure: toward meaningful clinical targets in patients with shock. Crit Care Med. 2014 May;42(5):1241-51. doi:10.1097/CCM.0000000000000324.

Hilbert L, Cumarasamy S, Zitouni NB, Mackey MC, Lauzon AM. The kinetics of mechanically coupled myosins exhibit group size-dependent regimes. Biophys J. 2013 Sep 17;105(6):1466-74. doi: 10.1016/j.bpj.2013.07.054.

Halbrich M, Ben-Shoshan M, McCusker CAutoimmune hemolytic anemia (AHA) in a teenager: A wolf in sheep’s clothing. Eur J Haematol. 2013 Sep;91(3):262-4. doi: 10.1111/ejh.12148. Epub 2013 Jun 28.

Mazer BIs there a place for B cells as regulators of immune tolerance in allergic diseases? Clin Exp Allergy. 2014 Apr;44(4):469-71. doi: 10.1111/cea.12274. No abstract available.

March 2014

Matusovsky OS, Nakada EM, Kachmar L, Fixman ED,  Lauzon AM. CD4+ T cells enhance the unloaded shortening velocity of airway smooth muscle by altering the contractile protein expression. J Physiol. 2014 Mar 31. [Epub ahead of print]

Gore V, Gravel S, Cossette C, Patel P, Chourey S, Ye Q, Rokach J, Powell WS. Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. J Med Chem. 2014 Jan 23;57(2):364-77. doi: 10.1021/jm401292m. Epub 2014 Jan 6.

Chang Y, Al-Alwan L, Audusseau S, Chouiali F, Carlevaro-Fita J, Iwakura Y, Baglole CJEidelman DHHamid QGenetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 4. [Epub ahead of print]

Gouspillou G, Hepple RT. Facts and Controversies in Our Understanding of How Caloric Restriction Impacts the Mitochondrion. Exp Gerontol. 2013 Oct;48(10):1075-84. doi: 10.1016/j.exger.2013.03.004. Epub 2013 Mar 21. Review.

Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE.International Union of Basic and Clinical Pharmacology. Update on Leukotriene, Lipoxin and Oxoeicosanoid Receptors: IUPHAR Review “X”. Br J Pharmacol. 2014 Mar 3. doi: 10.1111/bph.12665. [Epub ahead of print]

February 2014

Pamidi S, Pinto LM, Marc I, Benedetti A, Schwartzman K, Kimoff RJ. Maternal Sleep-Disordered Breathing and Adverse Pregnancy Outcomes – A Systematic Review and Meta-analysis. Am J Obstet Gynecol. 2014 Jan;210(1):52.e1-52.e14. doi: 10.1016/j.ajog.2013.07.033. Epub 2013 Aug 2. Review.

Schönberger K, Ludwig MS, Wildner M, Weissbrich B. Epidemiology of subacute sclerosing panencephalitis (SSPE) in Germany from 2003 to 2009: a risk estimation. PLoS One. 2013 Jul 9;8(7):e68909. doi: 10.1371/journal.pone.0068909. Print 2013.

McCuaig S, Martin JG. How the airway smooth muscle in cystic fibrosis reacts in proinflammatory conditions: implications for airway hyper-responsiveness and asthma in cystic fibrosis. Lancet Respir Med. 2013 Apr;1(2):137-47. doi: 10.1016/S2213-2600(12)70058-9. Epub 2013 Jan 30. Review.

Martel G, Rousseau S. TPL2 signalling: from Toll-like receptors-mediated ERK1/ERK2 activation to Cystic Fibrosis Lung disease. Int J Biochem Cell Biol. 2014 Feb 13. pii: S1357-2725(14)00045-4. doi: 10.1016/j.biocel.2014.02.002. [Epub ahead of print] Review.

Martel G, Roussel L, Rousseau S. The protein kinases TPL2 and EGFR contribute to ERK1/ERK2 hyper-activation in CFTRΔF508-expressing airway epithelial cells exposed to Pseudomonas aeruginosa. Biochem Biophys Res Commun. 2013 Oct 25. pii: S0006-291X(13)01702-6. doi: 10.1016/j.bbrc.2013.10.030. [Epub ahead of print]

Purves-Smith FM, Sgarioto N, Hepple RT. Fiber Typing in Aging Muscle. Exerc Sport Sci Rev. 2014 Feb 6. [Epub ahead of print]

Magder S. Is all on the level? Hemodynamics during supine versus prone ventilation. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1390-1. doi: 10.1164/rccm.201311-1957ED. No abstract available.

January 2014

Dhuban KB, d’Hennezel E, Ben-Shoshan M, McCusker C, Clarke A, Fiset P, Mazer B, Piccirillo CA. Altered T Helper 17 Responses in Children with Food Allergy. Int Arch Allergy Immunol. 2013;162(4):318-22. doi: 10.1159/000354028. Epub 2013 Oct 25.

Rahman M, Mofarrahi M, Kristof AS, Nkengfac B, Harel S, Hussain SNReactive oxygen species regulation of autophagy in skeletal muscles. Antioxid Redox Signal. 2014 Jan 20;20(3):443-59. doi: 10.1089/ars.2013.5410.

Guo Y, Gosker HR, Schols AM, Kapchinsky S, Bourbeau J, Sandri M, Jagoe RT, Debigaré R, Maltais F, Taivassalo T, Hussain SN. Autophagy in locomotor muscles of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Dec 1;188(11):1313-20. doi: 10.1164/rccm.201304-0732OC

Verway M, Bouttier M, Wang TT, Carrier M, Calderon M, An BS, Devemy E, McIntosh F, Divangahi M, Behr MA, White JH. Vitamin D Induces Interleukin-1β Expression: Paracrine Macrophage Epithelial Signaling Controls M. tuberculosis Infection. PLoS Pathog. 2013;9(6):e1003407. doi: 10.1371/journal.ppat.1003407. Epub 2013 Jun 6.

Lewkowich IP, Lajoie S, Stoffers SL, Suzuki Y, Richgels PK, Dienger K, Sproles AA, Yagita H, Hamid Q, Wills-Karp M. PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production. Mucosal Immunol. 2013 Jul;6(4):728-39. doi: 10.1038/mi.2012.111. Epub 2012 Nov 14.

Lavoie-Lamoureux A, Martin JG, Lavoie JP. Characterization of arginase expression by equine neutrophils. Vet Immunol Immunopathol. 2013 Dec 30. pii: S0165-2427(13)00333-4. doi: 10.1016/j.vetimm.2013.12.007. [Epub ahead of print]

December 2013

Gore V, Gravel S, Cossette C, Patel P, Chourey S, Ye Q, Rokach J, Powell WSInhibition of 5-oxo-ETE-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. J Med Chem. 2013 Dec 18. [Epub ahead of print]

Campoli P, Perlin DS, Kristof AS, White TC, Filler SG, Sheppard DC. Pharmacokinetics of posaconazole within epithelial cells and fungi: Insights into potential mechanisms of action during treatment and prophylaxis. J Infect Dis. 2013 Nov 15;208(10):1717-28. doi: 10.1093/infdis/jit358. Epub 2013 Aug 1.

Magder S. Is All on the Level? Hemodynamics during Supine versus Prone Ventilation. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1390-1. doi: 10.1164/rccm.201311-1957ED. No abstract available.

Al-Ramli W, Al Samri M, Hamid Q. Th-17 cell-related cytokines’ potential role in the pathogenesis of severe asthma. J Asthma. 2008;45 Suppl 1:41-4. Review.

Mofarrahi M, Sigala I, Vassilakopoulos T, Harel S, Guo Y, Debigare R, Maltais F, Hussain SNAngiogenesis-related factors in skeletal muscles of COPD patients: roles of angiopoietin-2. J Appl Physiol (1985). 2013 May;114(9):1309-18. doi: 10.1152/japplphysiol.00954.2012. Epub 2013 Jan 10.

Hussain SN, Sandri M. Role of autophagy in COPD skeletal muscle dysfunction. J Appl Physiol (1985). 2013 May;114(9):1273-81. doi: 10.1152/japplphysiol.00893.2012. Epub 2012 Oct 18. Review.

November 2013

Wright KJ, Thomas MM, Betik AC, Belke D, Hepple RTExercise Training Initiated in Late Middle Age Attenuates Cardiac Fibrosis and Advanced Glycation End-product Accumulation in Senescent Rats. Exp Gerontol. 2013 Nov 23. doi:pii: S0531-5565(13)00335-5. 10.1016/j.exger.2013.11.006. [Epub ahead of print]

Al-Alwan LA, Chang Y, Mogas A, Halayko AJ, Baglole CJ, Martin JG, Rousseau S, Eidelman DHHamid Q. Differential Roles of CXCL2 and CXCL3 and Their Receptors in Regulating Normal and Asthmatic Airway Smooth Muscle Cell Migration. J Immunol. 2013 Sep 1;191(5):2731-41. doi: 10.4049/jimmunol.1203421. Epub 2013 Jul 31.

Flaczyk A, Duerr CU, Shourian M, Lafferty EI, Fritz JH, Qureshi STIL-33 Signaling Regulates Innate and Adaptive Immunity to Cryptococcus neoformans. J Immunol. 2013 Sep 1;191(5):2503-13. doi: 10.4049/jimmunol.1300426. Epub 2013 Jul 26.

Rahman M, Mofarrahi M, Kristof AS, Nkengfac B, Harel S, Hussain S Dr. REACTIVE OXYGEN SPECIES REGULATION OF AUTOPHAGY IN SKELETAL MUSCLES. Antioxid Redox Signal. 2013 Nov 1. [Epub ahead of print]

Roman HN, Zitouni NB, Kachmar L, Ijpma G, Hilbert L, Matusovskiy O, Benedetti A, Sobieszek A, Lauzon AM. Unphosphorylated calponin enhances the binding force of unphosphorylated myosin to actin. Biochim Biophys Acta. 2013 Oct;1830(10):4634-41. doi: 10.1016/j.bbagen.2013.05.042. Epub 2013 Jun 6.

Potter BJ, Deverenne B, Doucette S, Fergusson D, Magder S; for the Canadian Critical Care Trials Group. Cardiac output responses in a flow-driven protocol of resuscitation following cardiac surgery. J Crit Care. 2013 Jun;28(3):265-9. doi: 10.1016/j.jcrc.2012.09.008. Epub 2012 Nov 14

October 2013

Shahin J, Bielinski M, Guichon C, Flemming C,  Kristof AS. Suspected ventilator-associated respiratory infection in severely ill patients: a prospective observational study. Crit Care. 2013 Oct 22;17(5):R251. [Epub ahead of print]

Côté I, Trojan D, Kaminska M, Cardoso M, Benedetti A, Weiss D, Robinson A, Bar-Or A, Lapierre Y, Kimoff RImpact of sleep disorder treatment on fatigue in multiple sclerosis. Mult Scler. 2013 Apr;19(4):480-9. doi: 10.1177/1352458512455958. Epub 2012 Aug 22

Kyoh S, Venkatesan N, Poon AH, Nishioka M, Lin TY, Baglole CJ, Eidelman DH, Hamid Q. Are leukocytes in asthmatic patients aging faster? A study of telomere length and disease severity. J Allergy Clin Immunol. 2013 Aug;132(2):480-2.e2. doi: 10.1016/j.jaci.2013.02.010. Epub 2013 Mar 25. No abstract available.

Venkatesan N, Tsuchiya K, Kolb M, Farkas L, Bourhim M, Ouzzine M, Ludwig MSGlycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1-Induced Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2013 Oct 15. [Epub ahead of print]

Desjardins M, Mazer BD. B-cell memory and primary immune deficiencies: interleukin-21 related defects. Curr Opin Allergy Clin Immunol. 2013 Oct 12. [Epub ahead of print]

Lee N, Qureshi ST. Other Viral Pneumonias: Coronavirus, Respiratory Syncytial Virus, Adenovirus, Hantavirus. Crit Care Clin. 2013 Oct;29(4):1045-1068. doi: 10.1016/j.ccc.2013.07.003. Epub 2013 Aug 9.

Septmber 2013

Shalaby KH, Allard-Coutu A, O’Sullivan MJ, Nakada E, Qureshi ST, Day BJ, Martin JG. Inhaled Birch Pollen Extract Induces Airway Hyperresponsiveness via Oxidative Stress but Independently of Pollen-Intrinsic NADPH Oxidase Activity, or the TLR4-TRIF Pathway. J Immunol. 2013 Jul 15;191(2):922-33. doi: 10.4049/jimmunol.1103644. Epub 2013 Jun 17.

Al-Muhsen S, Letuve S, Vazquez-Tello A, Pureza MA, Al-Jahdali H, Bahammam AS, Hamid Q, Halwani R.Th17 Cytokines induce pro-fibrotic cytokines release from human eosinophils. Respir Res. 2013 Mar 13;14:34. doi: 10.1186/1465-9921-14-34.

Hirota N, Martin JG. Mechanisms of airway remodeling. Chest. 2013 Sep;144(3):1026-32. doi: 10.1378/chest.12-3073.

August 2013

Rousseau MC, Hsu RY, Spicer JD, McDonald B, Chan CH, Perera RM, Giannias B, Chow SC, Rousseau S, Law S, Ferri LE. Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner.Surgery. 2013 Jul;154(1):69-77. doi: 10.1016/j.surg.2013.03.006.

Al Rushood M, McCusker C, Mazer B, Alizadehfar R, Grimbacher B, Depner M, Ben-Shoshan M.Autosomal Dominant Cases of Chronic Mucocutaneous Candidiasis Segregates with Mutations of Signal Transducer and Activator of Transcription 1, But Not of Toll-Like Receptor 3. J Pediatr. 2013 Jul;163(1):277-9. doi: 10.1016/j.jpeds.2013.02.040. Epub 2013 Mar 26.

Honeyman L, Bazett M, Tomko TG, Haston CK. MicroRNA profiling implicates the insulin-like growth factor pathway in bleomycin-induced pulmonary fibrosis in mice. Fibrogenesis Tissue Repair. 2013 Aug 29;6(1):16. [Epub ahead of print]

Halwani R, Vazquez-Tello A, Sumi Y, Pureza MA, Bahammam A, Al-Jahdali H, Soussi-Gounni A, Mahboub B, Al-Muhsen S, Hamid Q. Eosinophils Induce Airway Smooth Muscle Cell Proliferation. J Clin Immunol. 2013 Apr;33(3):595-604. doi: 10.1007/s10875-012-9836-3. Epub 2012 Nov 23.

Petrof BJ. Diaphragmatic dysfunction in the intensive care unit: caught in the cross-fire between sepsis and mechanical ventilation. Crit Care. 2013 Aug 27;17(4):R181. [Epub ahead of print]

Siddiqui S, Novali M, Tsuchiya K, Hirota N, Geller BJ, McGovern TK, Risse PA, Jo T, Zeroual MA, Martin JG. The modulation of large airway smooth muscle phenotype and effects of epidermal growth factor receptor inhibition in the repeatedly allergen-challenged rat. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L853-62. doi: 10.1152/ajplung.00047.2012. Epub 2013 Apr 19.

Kaminska M, Kimoff R, Trojan D. Reply: ‘Obstructive sleep apnea is associated with fatigue in multiple sclerosis’ by Kaminska et al. Mult Scler. 2013 Mar;19(3):374-5. doi: 10.1177/1352458512446038. Epub 2012 May 4. No abstract available

July 2013

Vazquez-Tello A, Halwani R, Hamid Q, Al-Muhsen S. Glucocorticoid Receptor-Beta Up-Regulation and Steroid Resistance Induction by IL-17 and IL-23 Cytokine Stimulation in Peripheral Mononuclear Cells. J Clin Immunol. 2013 Feb;33(2):466-78. doi: 10.1007/s10875-012-9828-3. Epub 2012 Nov 16.

Paun A, Lemay AM, Tomko TG, Haston CK. Association Analysis Reveals Genetic Variation Altering Bleomycin-Induced Pulmonary Fibrosis in Mice. Am J Respir Cell Mol Biol. 2012 Dec 13. [Epub ahead of print]

Gore V, Patel P, Chang CT, Sivendran S, Kang N, Ouedraogo YP, Gravel S, Powell WS, Rokach J. 5-Oxo-ETE Receptor Antagonists. J Med Chem. 2013 May 9;56(9):3725-32. doi: 10.1021/jm400480j. Epub 2013 Apr 26.

Paun A, Haston CK. Genomic and genome-wide association of susceptibility to radiation-induced fibrotic lung disease in mice. Radiother Oncol. 2012 Dec;105(3):350-7. doi: 10.1016/j.radonc.2012.08.004. Epub 2012 Sep 4.

Massoud AH, Kaufman GN, Mourad MW, Piccirillo C,  Mazer BD. Reply. J Allergy Clin Immunol. 2013 Apr;131(4):1257-8. doi: 10.1016/j.jaci.2013.01.032. Epub 2013 Mar 1. No abstract available.

Rousseau MC, Hsu RY, Spicer JD, McDonald B, Chan CH, Perera RM, Giannias B, Chow SC, Rousseau S, Law S, Ferri LE. Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner. Surgery. 2013 Jul;154(1):69-77. doi: 10.1016/j.surg.2013.03.006.

Lescot T, Karvellas CJ, Chaudhury P, Tchervenkov J, Paraskevas S, Barkun J, Metrakos P, Goldberg PMagder SPostoperative delirium in the intensive care unit predicts worse outcomes in liver transplant recipients. Can J Gastroenterol. 2013 Apr;27(4):207-12.

Divangahi M, Behar SM, Remold H. Dying to live: how the death modality of the infected macrophage affects immunity to tuberculosis. Adv Exp Med Biol. 2013;783:103-20. doi: 10.1007/978-1-4614-6111-1_6. Review.

Bates G, Sigurdardottir S, Kachmar L, Zitouni NB, Benedetti A, Petrof BJ, Rassier DE, Lauzon AMMolecular, cellular, and muscle strip mechanics of the mdx mouse diaphragm. Am J Physiol Cell Physiol. 2013 May 1;304(9):C873-80. doi: 10.1152/ajpcell.00220.2012. Epub 2013 Feb 20.

Lin TY, Poon AH, Hamid QAsthma phenotypes and endotypes. Curr Opin Pulm Med. 2013 Jan;19(1):18-23. doi: 10.1097/MCP.0b013e32835b10ec. Review.

June 2013

Cousens LP, Tassone R, Mazer B, Ramachandiran V, Scott DW, De Groot AS. Tregitope update: Mechanism of action parallels IVIg. Autoimmun Rev. 2013 Jan;12(3):436-43. doi: 10.1016/j.autrev.2012.08.017. Epub 2012 Aug 28. Review.

Halwani R, Al-Muhsen S, Hamid QT helper 17 cells in airway diseases: from laboratory bench to bedside. Chest. 2013 Feb 1;143(2):494-501. doi: 10.1378/chest.12-0598.

Cousens LP, Najafian N, Mingozzi F, Elyaman W, Mazer B, Moise L, Messitt TJ, Su Y, Sayegh M, High K, Khoury SJ, Scott DW, De Groot AS. In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity. J Clin Immunol. 2013 Jan;33 Suppl 1:S43-9. doi: 10.1007/s10875-012-9762-4. Epub 2012 Sep 2. Review.

Johnsen VL, Belke DD, Hughey CC, Hittel DS, Hepple RT, Koch LG, Britton SL, Shearer J. Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity. Physiol Genomics. 2013 Jan 7;45(1):17-25. doi: 10.1152/physiolgenomics.00111.2012. Epub 2012 Nov 6.

Schönberger K, Ludwig MS, Wildner M, Kalies H. Timely MMR vaccination in infancy: influence of attitudes and medical advice on the willingness to vaccinate. Klin Padiatr. 2012 Nov;224(7):437-42. doi: 10.1055/s-0032-1321731. Epub 2012 Jul 20.

May 2013 

Kinyanjui MW, Shan J, Nakada EM, Qureshi ST,  Fixman ED. Dose-Dependent Effects of IL-17 on IL-13-Induced Airway Inflammatory Responses and Airway Hyperresponsiveness. J Immunol. 2013 Apr 15;190(8):3859-68. doi: 10.4049/jimmunol.1200506. Epub 2013 Mar 18.

Ghezzi CE, Risse PA, Marelli B, Muja N, Barralet JE, Martin JG, Nazhat SN. An airway smooth muscle cell niche under physiological pulsatile flow culture using a tubular dense collagen construct. Biomaterials. 2013 Mar;34(8):1954-66. doi: 10.1016/j.biomaterials.2012.11.025. Epub 2012 Dec 17.

Kunwar A, Jain VK, Priyadarsini KI, Haston CKA Selenocysteine Derivative Therapy Affects Radiation-Induced Pneumonitis in the Mouse. Am J Respir Cell Mol Biol. 2013 May 30. [Epub ahead of print]

Stefanov AN, Fox J, Haston CKPositional cloning reveals strain-dependent expression of trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice. PLoS Genet. 2013;9(1):e1003203. doi: 10.1371/journal.pgen.1003203. Epub 2013 Jan 17.

Arshad SH, Dharmage SC, Ferreira F, Fixman ED, Gadermaier G, Hauser M, Sampson AP, Teran LM, Wallner M, Wardlaw AJ. Developments in the field of allergy in 2011 through the eyes of Clinical and Experimental Allergy. Clin Exp Allergy. 2012 Dec;42(12):1697-723. doi: 10.1111/cea.12037. Review.

Mofarrahi M, Sigala I, Guo Y, Godin R, Davis EC, Petrof B, Sandri M, Burelle Y, Hussain SN. Autophagy and skeletal muscles in sepsis. PLoS One. 2012;7(10):e47265. doi: 10.1371/journal.pone.0047265. Epub 2012 Oct 9.

Jobin V, Rigau J, Beauregard J, Farre R, Monserrat J, Bradley TD, Kimoff RJEvaluation of upper airway patency during cheyne-stokes breathing in heart failure patients. Eur Respir J. 2012 Dec;40(6):1523-30. doi: 10.1183/09031936.00060311. Epub 2012 May 17.

Boncoeur E, Bouvet G, Migneault F, Tardif V, Ferraro P, Radzioch D, de Sanctis JB, Eidelman DH, Govindaraju K, Dagenais A, Berthiaume Y. Induction of Nitric Oxide Synthase Expression By Lipopolysaccharide is Mediated by Calcium-dependent PKCα-β1 in Alveolar Epithelial Cells. Am J Physiol Lung Cell Mol Physiol. 2013 May 17. [Epub ahead of print]

Kalganov A, Shalabi N, Zitouni N, Kachmar LH, Lauzon AM, Rassier DE. Forces measured with micro-fabricated cantilevers during actomyosin interactions produced by filaments containing different myosin isoforms and loop 1 structures. Biochim Biophys Acta. 2013 Mar;1830(3):2710-9.

O’Keefe AW, McCusker C, Ben-Shoshan M. Critical upper airway obstruction in sporadic angioedema responding to C1-esterase inhibitor. BMJ Case Rep. 2013 May 8;2013. doi:pii: bcr2013009616. 10.1136/bcr-2013-009616.

Al Heialy S, Risse PA, Zeroual MA, Roman HN, Tsuchiya K, Siddiqui S, Laporte SA, Martin JGT Cell-Induced Airway Smooth Muscle Cell Proliferation via the Epidermal Growth Factor Receptor.Am J Respir Cell Mol Biol. 2013 May 8. [Epub ahead of print]

Kaltsakas G, Antoniou E, Palamidas AF, Gennimata SA, Paraskeva P, Smyrnis A, Koutsoukou A, Milic-Emili J, Koulouris NG. Dyspnea and respiratory muscle strength in end-stage liver disease. World J Hepatol. 2013 Feb 27;5(2):56-63. doi: 10.4254/wjh.v5.i2.56.

Abdel-Samad D, Perreault C, Ahmarani L, Avedanian L, Bkaily G, Magder S, D’Orléans-Juste P, Jacques D. Differences in neuropeptide Y-induced secretion of endothelin-1 in left and right human endocardial endothelial cells. Neuropeptides. 2012 Dec;46(6):373-82. doi: 10.1016/j.npep.2012.09.003. Epub 2012 Oct 26.

Purves-Smith FM, Solbak NM, Rowan SL, Hepple RTSevere atrophy of slow myofibers in aging muscle is concealed by myosin heavy chain co-expression. Exp Gerontol. 2012 Dec;47(12):913-8. doi: 10.1016/j.exger.2012.07.013. Epub 2012 Aug 3.

Picard M, Wright KJ, Ritchie D, Thomas MM, Hepple RTMitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium. PLoS One. 2012;7(8):e43003. doi: 10.1371/journal.pone.0043003. Epub 2012 Aug 9.

April 2013

Sigala I, Zacharatos P, Boulia S, Toumpanakis D, Michailidou T, Parthenis D, Roussos C, Papapetropoulos A, Hussain SN, Vassilakopoulos T. Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing. J Appl Physiol. 2012 Nov;113(10):1594-603. doi: 10.1152/japplphysiol.00233.2012. Epub 2012 Sep 6.

Lescot T, Karvellas CJ, Chaudhury P, Tchervenkov J, Paraskevas S, Barkun J, Metrakos P, Goldberg P, Magder S. Postoperative delirium in the intensive care unit predicts worse outcomes in liver transplant recipients. Can J Gastroenterol. 2013 Apr;27(4):207-12.

Fox J, Bergeron ME, Haston CKGenetic Deficiency in Complement Component 4b Does Not Alter Radiation-Induced Lung Disease in Mice. Radiat Res. 2013 Feb;179(2):146-50. doi: 10.1667/RR3072.1. Epub 2012 Dec 21.

Chang Y, Al-Alwan L, Risse PA, Halayko AJ, Martin JG, Baglole CJ, Eidelman DH, Hamid Q. Th17-associated cytokines promote human airway smooth muscle cell proliferation.FASEB J. 2012 Dec;26(12):5152-60. doi: 10.1096/fj.12-208033. Epub 2012 Aug 16.

Castillo R, Castillo E, Fuentes D, Ahmad M, Wood AM, Ludwig MS, Guerrero T. A reference dataset for deformable image registration spatial accuracy evaluation using the COPDgene study archive.Phys Med Biol. 2013 Apr 10;58(9):2861-2877. [Epub ahead of print]

March 2013

Beaudoin T, Lafayette S, Nguyen DRousseau S. Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells.Biochem Biophys Res Commun. 2012 Nov 9;428(1):150-4. doi: 10.1016/j.bbrc.2012.10.030. Epub 2012 Oct 12.

Martel G, Bérubé J,  Rousseau SThe Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs). PLoS One. 2013;8(3):e59116. doi: 10.1371/journal.pone.0059116. Epub 2013 Mar 19.

Godin R, Daussin FN, Matecki S, Li T, Petrof BJ, Burelle Y. PGC1α gene transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdxmouse skeletal muscle. J Physiol. 2012 Nov 1;590(Pt 21):5487-502. doi: 10.1113/jphysiol.2012.240390. Epub 2012 Aug 20.

Divangahi M, Behar SM, Remold H. Dying to live: how the death modality of the infected macrophage affects immunity to tuberculosis. Adv Exp Med Biol. 2013;783:103-20. doi: 10.1007/978-1-4614-6111-1_6.

February 2013

Fox J, Haston CKCXC Receptor 1 and 2 and Neutrophil Elastase Inhibitors Alter Radiation-induced Lung Disease in the Mouse. Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):215-22. doi: 10.1016/j.ijrobp.2012.02.024. Epub 2012 Aug 25.

Carroll SF, Lafferty EI, Flaczyk A, Fujiwara M, Homer R, Morgan K, Loredo-Osti JC, Qureshi STSusceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9. Infect Immun. 2012 Dec;80(12):4167-76. doi: 10.1128/IAI.00417-12. Epub 2012 Sep 17.

Picard M, Jung B, Liang F, Azuelos I, Hussain SGoldberg P, Godin R, Danialou G, Chaturvedi R, Rygiel K, Matecki S, Jaber S, Des Rosiers C, Karpati G, Ferri L, Burelle Y, Turnbull DM, Taivassalo T, Petrof BJMitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation. Am J Respir Crit Care Med. 2012 Dec 1;186(11):1140-9. doi: 10.1164/rccm.201206-0982OC. Epub 2012 Sep 28.

January 2013

Poon AH, Gong L, Brasch-Andersen C, Litonjua AA, Raby BA, Hamid Q, Laprise C, Weiss ST, Altman RB, Klein TE. Very important pharmacogene summary for VDR. Pharmacogenet Genomics. 2012 Oct;22(10):758-63. Review. No abstract available.

Massoud AH, Guay J, Shalaby KH, Bjur E, Ablona A, Chan D, Nouhi Y, McCusker CT, Mourad MW, Piccirillo CA, Mazer BDIntravenous immunoglobulin attenuates airway inflammation through induction of forkhead box protein 3-positive regulatory T cells. J Allergy Clin Immunol. 2012 Jun;129(6):1656-65.e3. doi: 10.1016/j.jaci.2012.02.050. Epub 2012 May 5

Trojan DA, Kaminska M, Bar-Or A, Benedetti A, Lapierre Y, Da Costa D, Robinson A, Cardoso M, Schwartzman K, Kimoff RJPolysomnographic measures of disturbed sleep are associated with reduced quality of life in multiple sclerosis. J Neurol Sci. 2012 May 15;316(1-2):158-63. doi: 10.1016/j.jns.2011.12.013. Epub 2012 Jan 16.

Leclere M, Lavoie-Lamoureux A, Joubert P, Relave F, Lanctot Setlakwe E, Beauchamp G, Couture C, Martin JG, Lavoie JP. Corticosteroids and Antigen Avoidance Decrease Airway Smooth Muscle Mass in an Equine Asthma Model. Am J Respir Cell Mol Biol. 2012 Nov;47(5):589-96. doi: 10.1165/rcmb.2011-0363OC. Epub 2012 Jun 21.

Ijpma G, Matusovsky O, Lauzon AM. Accumulating evidence for increased velocity of airway smooth muscle shortening in asthmatic airway hyperresponsiveness. J Allergy (Cairo). 2012;2012:156909. doi: 10.1155/2012/156909. Epub 2012 Dec 25.

Carpe N, Mandeville I, Kho AT, Qiu W, Martin JG, Tantisira KG, Raby BA, Weiss ST, Kaplan F. Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normo-responsive rat pups. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15;303(10):L899-911. doi: 10.1152/ajplung.00179.2012. Epub 2012 Sep 14.

Alvisi V, Marangoni E, Zannoli S, Uneddu M, Uggento R, Farabegoli L, Ragazzi R, Milic-Emili J, Belloni GP, Alvisi R, Volta CA. Pulmonary Function and Expiratory Flow Limitation in Acute Cervical Cord Injury. Arch Phys Med Rehabil. 2012 Nov;93(11):1950-6. doi: 10.1016/j.apmr.2012.04.015. Epub 2012 Apr 27.

Hepple RTLast Word on Viewpoint: Muscle atrophy is not always sarcopenia. J Appl Physiol. 2012 Aug 15;113(4):685. doi: 10.1152/japplphysiol.00682.2012. No abstract available.

Hepple RT. Muscle atrophy is not always sarcopenia. J Appl Physiol. 2012 Aug 15;113(4):677-9. doi: 10.1152/japplphysiol.00304.2012. Epub 2012 Apr 19. No abstract available.

December 2012

Macsharry J, O’Mahony C, Shalaby KH, Sheil B, Karmouty-Quintana H, Shanahan F, Martin JGImmunomodulatory effects of feeding with Bifidobacterium longum on allergen-induced lung inflammation in the mouse. Pulm Pharmacol Ther. 2012 Aug;25(4):325-34. doi: 10.1016/j.pupt.2012.05.011. Epub 2012 Jun 13.

Kalganov A, Shalabi N, Zitouni N, Kachmar LH,  Lauzon AM, Rassier DE. Forces measured with micro-fabricated cantilevers during actomyosin interactions produced by filaments containing different myosin isoforms and loop 1 structure. Biochim Biophys Acta. 2012 Dec 6. doi:pii: S0304-4165(12)00342-X. 10.1016/j.bbagen.2012.11.022. [Epub ahead of print]

Roussel L, Farias R, Rousseau S. IL-33 is expressed in epithelia from patients with cystic fibrosis and potentiates neutrophil recruitment. J Allergy Clin Immunol. 2012 Dec 5. doi:pii: S0091-6749(12)01687-9. 10.1016/j.jaci.2012.10.019. [Epub ahead of print] No abstract available.

Al-Alwan LA, Chang Y, Baglole CJ, Risse PA, Halayko AJ, Martin JGEidelman DHHamid QAutocrine-regulated airway smooth muscle cell migration is dependent on IL-17-induced growth-related oncogenes. J Allergy Clin Immunol. 2012 Oct;130(4):977-85.e6. doi: 10.1016/j.jaci.2012.04.042. Epub 2012 Jun 13.

Shalaby KH, Jo T, Nakada E, Allard-Coutu A, Tsuchiya K, Hirota N, Qureshi ST, Maghni K, Rioux CR, Martin JGICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma. J Immunol. 2012 Aug 20. [Epub ahead of print]

Lescot T, Karvellas C, Beaussier M, Magder SAcquired liver injury in the intensive care unit.Anesthesiology. 2012 Oct;117(4):898-904. Review. No abstract available.

Pauly M, Daussin F, Burelle Y, Li T, Godin R, Fauconnier J, Koechlin-Ramonatxo C, Hugon G, Lacampagne A, Quivy M, Liang F, Hussain S, Matecki S, Petrof BJAMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm. Am J Pathol. 2012 Aug;181(2):583-92. doi: 10.1016/j.ajpath.2012.04.004. Epub 2012 Jun 5.

Kaminska M, Kimoff R, Benedetti A, Robinson A, Bar-Or A, Lapierre Y, Schwartzman K, Trojan D. Obstructive sleep apnea is associated with fatigue in multiple sclerosis. Mult Scler. 2012 Aug;18(8):1159-69. doi: 10.1177/1352458511432328. Epub 2011 Dec 19.

November 2012

Al-Khayyat AI, Al-Anazi M, Warsy A, Vazquez-Tello A, Alamri AM, Halwani R, Alangari A, Al-Frayh A, Hamid Q, Al-Muhsen S. T1 and T2 ADAM33 single nucleotide polymorphisms and the risk of childhood asthma in a Saudi Arabian population: a pilot study. Ann Saudi Med. 2012 Sep-Oct;32(5):479-86. doi: 10.5144/0256-4947.2012.479.

Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol. 2012 Sep;130(3):647-654.e10. doi: 10.1016/j.jaci.2012.06.025. Epub 2012 Aug 1.

Poon A, Eidelman D, Laprise C, Hamid QATG5, autophagy and lung function in asthma.Autophagy. 2012 Apr;8(4):694-5. doi: 10.4161/auto.19315. Epub 2012 Apr 1.

Lin TY, Poon AH, Hamid QAsthma phenotypes and endotypes. Curr Opin Pulm Med. 2012 Oct 30. [Epub ahead of print]

Mrozek S, Jung B, Petrof BJ, Pauly M, Roberge S, Lacampagne A, Cassan C, Thireau J, Molinari N, Futier E, Scheuermann V, Constantin JM, Matecki S, Jaber S. Rapid onset of specific diaphragm weakness in a healthy murine model of ventilator-induced diaphragmatic dysfunction. Anesthesiology. 2012 Sep;117(3):560-7.

October 2012

Magder S. Bench-to-bedside review: An approach to hemodynamic monitoring – Guyton at the bedside. Crit Care. 2012 Oct 29;16(5):236. [Epub ahead of print]

Ballarin A, Bazzan E, Hernandez Zenteno R, Turato G, Baraldo S, Zanovello D, Mutti E, Hogg JC, Saetta M, Cosio MG. Mast Cell Infiltration Discriminates Between Histopathological Phenotypes of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2012 Aug 1;186(3):233-9. doi: 10.1164/rccm.201112-2142OC. Epub 2012 Jun 7.

Magder S, Guerard B. Heart-lung interactions and pulmonary buffering: lessons from a computational modeling study. Respir Physiol Neurobiol. 2012 Jul 1;182(2-3):60-70. doi: 10.1016/j.resp.2012.05.011. Epub 2012 May 15.

Tazzeo T, Bates G, Roman HN, Lauzon AM, Khasnis MD, Eto M, Janssen LJ. Caffeine relaxes smooth muscle through actin depolymerization. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L334-42. doi: 10.1152/ajplung.00103.2012. Epub 2012 Jun 8.

Hussain SN, Sandri M. Role of autophagy in COPD skeletal muscle dysfunction. J Appl Physiol. 2012 Oct 18. [Epub ahead of print]

Poon AH, Hamid QAsthma endotypes: the right direction towards personalized medicine for asthma. Expert Rev Clin Immunol. 2012 Sep;8(7):595-6. doi: 10.1586/eci.12.57. No abstract available.

Fredriksson K, Fielhaber JA, Lam JK, Yao X, Meyer KS, Keeran KJ, Zywicke GJ, Qu X, Yu ZX, Moss J, Kristof AS, Levine SJ. Paradoxical effects of rapamycin on experimental house dust mite-induced asthma. PLoS One. 2012;7(5):e33984. doi: 10.1371/journal.pone.0033984. Epub 2012 May 25.

Tsuchiya K, Siddiqui S, Risse PA, Hirota N, Martin JGThe presence of LPS in OVA inhalations affects airway inflammation and AHR but not remodeling in a rodent model of asthma. Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L54-63. doi: 10.1152/ajplung.00208.2011. Epub 2012 Apr 20.

Cosio MG, Saetta M. Evasion of copd in smokers. at what price? Eur Respir J. 2012 Jun;39(6):1298-303. doi: 10.1183/09031936.00135711. Epub 2011 Oct 17. Review

September 2012

Magder SProtocols, physiology, and trials of hydroxyethyl starch. N Engl J Med. 2012 Sep 27;367(13):1265; author reply 1267. No abstract available.

Chang NC, Nguyen M, Bourdon J, Risse PA, Martin J, Danialou G, Rizzuto R, Petrof BJ, Shore GC. Bcl-2-Associated Autophagy Regulator Naf-1 Required for Maintenance of Skeletal Muscle. Hum Mol Genet. 2012 May 15;21(10):2277-87. Epub 2012 Feb 15.

Risse PA, Kachmar L, Matusovsky OS, Novali M, Gil FR, Javeshghani S, Keary R, Haston CK, Michoud MC, Martin JGLauzon AM. Ileal Smooth Muscle Dysfunction and Remodeling in Cystic Fibrosis. Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G1-8. Epub 2012 Apr 26.

August 2012

Ismail H, Mofarrahi M, Echavarria R, Harel S, Verdin EM, Lim HW, Jin ZG, Sun J, Zeng H, Hussain SNAngiopoietin-1 and Vascular Endothelial Growth Factor Regulation of Leukocyte Adhesion to Endothelial Cells: Role of Nuclear Receptor-77. Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1707-16. Epub 2012 May 24.

Hepple RTLast Word on Viewpoint: Muscle atrophy is not always sarcopenia. J Appl Physiol. 2012 Aug;113(4):685.

Wardlaw AJ, O’Hehir RE, Corrigan CJ, Hamid QASpecial issue on severe asthma. Clin Exp Allergy. 2012 May;42(5):611.

Haston CKMouse genetic approaches applied to the normal tissue radiation response. Front Oncol. 2012;2:94. Epub 2012 Aug 7.

Al-Khayyat AI, Al-Anazi M, Warsy A, Vazquez-Tello A, Alamri AM, Halwani R, Alangari A, Al-Frayh A, Hamid Q, Al-Muhsen S. T1 and T2 ADAM33 single nucleotide polymorphisms and the risk of childhood asthma in a Saudi Arabian population: a pilot study. Ann Saudi Med. 2012 Sep;32(5):479-86.

July 2012

Lescot T, Karvellas C, Beaussier M, Magder SAcquired Liver Injury in the Intensive Care Unit. Anesthesiology. 2012 Jul 31. [Epub ahead of print] No abstract available.

Lavoie-Lamoureux A, Beauchamp G, Quessy S, Martin JG, Lavoie JP. Systemic inflammation and priming of peripheral blood leukocytes persist during clinical remission in horses with heaves. Vet Immunol Immunopathol. 2012 Mar 15;146(1):35-45. Epub 2012 Jan 31.

Contoli M, Kraft M, Hamid Q, Bousquet J, Rabe KF, Fabbri LM, Papi A. Do small airway abnormalities characterize asthma phenotypes? In search of proof. Clin Exp Allergy. 2012 Aug;42(8):1150-60. doi: 10.1111/j.1365-2222.2012.03963.x.

Bazzan E, Saetta M, Turato G, Borroni EM, Cancellieri C, Baraldo S, Savino B, Calabrese F, Ballarin A, Balestro E, Mantovani A, Cosio MG, Bonecchi R, Locati M. Expression of the atypical chemokine receptor D6 in human alveolar macrophages in Chronic Obstructive Pulmonary Disease. Chest. 2012 Jul 10. doi: 10.1378/chest.11-3220. [Epub ahead of print]

Al Ghouleh I, Magder SNADPH oxidase-derived superoxide destabilizes lipopolysaccharide-induced interleukin 8 mRNA via p38, extracellular signal-regulated kinase mitogen-activated protein kinase, and the destabilizing factor tristetraprolin. Shock. 2012 Apr;37(4):433-40.

Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q. Expression and regulation of CCL15 by human airway smooth muscle cells. Clin Exp Allergy. 2012 Jan;42(1):85-94. doi: 10.1111/j.1365-2222.2011.03894.x. Epub 2011 Nov 9.

Mrozek S, Jung B, Petrof BJ, Pauly M, Roberge S, Lacampagne A, Cassan C, Thireau J, Molinari N, Futier E, Scheuermann V, Michel Constantin J, Matecki S, Jaber S. Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction. Anesthesiology. 2012 Jul 3. [Epub ahead of print]

Jaber S, Jung B, Matecki S, Petrof BJ. Clinical review: ventilator-induced diaphragmatic dysfunction–human studies confirm animal model findings! Crit Care. 2011 Mar 11;15(2):206. Review

Hamid Q. Pathogenesis of small airways in asthma. Respiration. 2012;84(1):4-11. Epub 2012 Jun 29.

Fielhaber JA, Tan J, Joung KB, Attias O, Huegel S, Bader M, Roux PP, Kristof ASRegulation of Karyopherin-α1 and nuclear import by mTOR. J Biol Chem. 2012 Apr 27;287(18):14325-35. Epub 2012 Mar 6.

June 2012

Kaufman GN, Massoud AH, Audusseau S, Banville-Langelier AA, Wang Y, Guay J, Garellek JA, Mourad W, Picirillo C, McCusker C, Mazer BDIntravenous immunoglobulin attenuates airway hyperresponsiveness in a murine model of allergic asthma. Clin Exp Allergy. 2011 May;41(5):718-28. doi: 10.1111/j.1365-2222.2010.03663.x. Epub 2011 Jan 24.

Byrne AM, Goleva E, Chouiali F, Kaplan MH, Hamid QA, Leung DY. Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis.Clin Exp Allergy. 2012 Apr;42(4):550-9. doi: 10.1111/j.1365-2222.2012.03956.x.

Alemayehu D, Casey PG, McAuliffe O, Guinane CM,  Martin JG, Shanahan F, Coffey A, Ross RP, Hill C.Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells. MBio. 2012 Mar 6;3(2):e00029-12. doi: 10.1128/mBio.00029-12. Print 2012.

Lauzon AM, Bates JH, Donovan G, Tawhai M, Sneyd J, Sanderson MJ. A multi-scale approach to airway hyperresponsiveness: from molecule to organ. Front Physiol. 2012;3:191. Epub 2012 Jun 11.

D’Antoni ML, Risse PA, Ferraro P, Martin JGLudwig MS. Effects of decorin and biglycan on human airway smooth muscle cell adhesion. Matrix Biol. 2012 Mar;31(2):101-12. Epub 2011 Dec 2.

McKim DA, Road J, Avendano M, Abdool S, Cote F, Duguid N, Fraser J, Maltais F, Morrison DL, O’Connell C, Petrof BJ, Rimmer K, Skomro R; Canadian Thoracic Society Home Mechanical Ventilation Committee. Home mechanical ventilation: a Canadian Thoracic Society clinical practice guideline. Can Respir J. 2011 Jul-Aug;18(4):197-215.

Pini L, Novali M, Modina D, Torregiani C, Ludwig MS, Veicsteinas A, Esposito F. Effect of training on airways inflammatory response and remodeling in a rat model. Respir Physiol Neurobiol. 2011 Dec 15;179(2-3):181-6. Epub 2011 Aug 7.

Fielhaber JA, Carroll SF, Dydensborg AB, Shourian M, Triantafillopoulos A, Harel S, Hussain SN, Bouchard M, Qureshi STKristof ASInhibition of Mammalian Target of Rapamycin Augments Lipopolysaccharide-Induced Lung Injury and Apoptosis. J Immunol. 2012 May 1;188(9):4535-42. Epub 2012 Mar 26.

Karmouty-Quintana H, Hassan M, Siddiqui S, Tsuchiya K, Risse PA, Xicota-Vila L, Marti-Solano M, Martin JGTreatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure. Am J Physiol Lung Cell Mol Physiol. 2012 Apr;302(8):L736-45. Epub 2012 Jan 27.

Siddiqui S, Tsuchiya K, Risse PA, Bullimore SR, Benedetti A, Martin JGSite of allergic airway narrowing and the influence of exogenous surfactant in the brown norway rat. PLoS One. 2012;7(1):e29381. Epub 2012 Jan 19

Bazett M, Stefanov AN, Paun A, Paradis J, Haston CKStrain-Dependent Airway Hyperresponsiveness and a Chromosome 7 Locus of Elevated Lymphocyte Numbers in Cystic Fibrosis Transmembrane Conductance Regulator-Deficient Mice. J Immunol. 2012 Mar 1;188(5):2297-304. Epub 2012 Jan 27.

Hirota N, Risse PA, Novali M, McGovern T, Al-Alwan L, McCuaig S, Proud D, Hayden P, Hamid Q, Martin JG. Histamine may induce airway remodeling through release of epidermal growth factor receptor ligands from bronchial epithelial cells. FASEB J. 2012 Apr;26(4):1704-16. Epub 2012 Jan 12.

May 2012

C, Tremblay C, FitzGerald M, Aaron SD, Leigh R, Boulet LP, Martin JG, Nair P, Olivenstein R, Chaboillez S. Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects. Can Respir J. 2011 Sep-Oct;18(5):278-82.

Picard M, Taivassalo T, Gouspillou G, Hepple RT. Mitochondria: isolation, structure and function. J Physiol. 2011 Sep 15;589(Pt 18):4413-21. doi: 10.1113/jphysiol.2011.212712. Epub 2011 Jun 27. Review.

Poon AH, Gong L, Brasch-Andersen C, Litonjua AA, Raby BA, Hamid Q, Laprise C, Weiss ST, Altman RB, Klein TE. Very important pharmacogene summary for VDR. Pharmacogenet Genomics. 2012 May 14. [Epub ahead of print] No abstract available.

Vazquez-Tello A, Halwani R, Li R, Nadigel J, Bar-Or A, Mazer BDEidelman DH, Al-Muhsen S, Hamid QIL-17A and IL-17F Expression in B Lymphocytes. Int Arch Allergy Immunol. 2012;157(4):406-16. Epub 2011 Nov 25.

Rowan SL, Rygiel K, Purves-Smith FM, Solbak NM, Turnbull DM, Hepple RTDenervation causes fiber atrophy and Myosin heavy chain co-expression in senescent skeletal muscle. PLoS One. 2012;7(1):e29082. Epub 2012 Jan 3.

McGarvey LP, Magder S, Burkhart D, Kesten S, Liu D, Manuel RC, Niewoehner DE. Cause-specific mortality adjudication in the UPLIFT(®) COPD trial: Findings and recommendations. Respir Med. 2011 Nov 17. [Epub ahead of print]

Poon AH, Hamid QPersonalized medicine for asthma: Are we there yet? Ann Thorac Med. 2012 Apr;7(2):55-6. No abstract available.

Venkatesan N, Siddiqui S, Jo T, Martin JG,  Ludwig MSAllergen-induced airway remodeling in brown norway rats: structural and metabolic changes in glycosaminoglycans. Am J Respir Cell Mol Biol. 2012 Jan;46(1):96-105.

April 2012

Pasternyk SM, D’Antoni ML, Venkatesan N, Siddiqui S, Martin JG, Ludwig MSDifferential effects of extracellular matrix and mechanical strain on airway smooth muscle cells from ovalbumin- vs saline-challenged Brown Norway rats. Respir Physiol Neurobiol. 2012 Apr 15;181(1):36-43. Epub 2012 Jan 31.

Poon AH, Eidelman DH, Martin JG, Laprise C,  Hamid Q. Pathogenesis of severe asthma.Clin Exp Allergy. 2012 May;42(5):625-37.

Poon AH, Chouiali F, Tse SM, Litonjua AA, Hussain SNBaglole CJEidelman DH, Olivenstein R, Martin JG, Weiss ST, Hamid Q, Laprise C. Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol. 2012 Feb;129(2):569-71. Epub 2011 Oct 29. No abstract available.

Bener A, Ehlayel MS, Tulic MK, Hamid QVitamin D Deficiency as a Strong Predictor of Asthma in Children. Int Arch Allergy Immunol. 2012;157(2):168-75. Epub 2011 Oct 6.

Picard M, Ritchie D, Thomas MM, Wright KJ,  Hepple RTAlterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles. Aging Cell. 2011 Dec;10(6):1047-55. doi: 10.1111/j.1474-9726.2011.00745.x.

March 2012

P, Al Abdallah Q, Robitaille R, Solis NV, Fielhaber JA, Kristof AS, Laverdiere M, Filler SG, Sheppard DC. Concentration of antifungal agents within host cell membranes: a new paradigm governing the efficacy of prophylaxis. Antimicrob Agents Chemother. 2011 Dec;55(12):5732-9. Epub 2011 Sep 19.

Rico de Souza A, Zago M, Pollock SJ, Sime PJ, Phipps RP, Baglole CJ. Genetic ablation of the aryl hydrocarbon receptor (AhR) causes cigarette smoke-induced mitochondrial dysfunction and apoptosis. J Biol Chem. 2011 Dec 16;286(50):43214-28. Epub 2011 Oct 7.

Picard M, Hepple RT, Burelle Y. Mitochondrial Functional Specialization in Glycolytic and Oxidative Muscle Fibers: Tailoring the Organelle for Optimal Function. Am J Physiol Cell Physiol. 2012 Feb;302(4):C629-41. Epub 2011 Oct 26. Review

Byrne AM, Goleva E, Chouiali F, Kaplan MH, Hamid QA, Leung DY. Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis. J Clin Exp Allergy. 2012 Apr;42(4):550-9. doi: 10.1111/j.1365-2222.2012.03956.x

Adler D, Gottfried SB, Bautin N, Mirkovic T, Schmidt M, Raux M, Pavlovic D, Similowski T, Demoule A. Repetitive magnetic stimulation of the phrenic nerves for diaphragm conditioning: a normative study of feasibility and optimal settings. Appl Physiol Nutr Metab. 2011 Dec;36(6):1001-8. Epub 2011 Oct 20.

Alemayehu D, Casey PG, McAuliffe O, Guinane CM,  Martin JG, Shanahan F, Coffey A, Ross RP, Hill C. Bacteriophages MR299-2 and NH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells. MBio. 2012 Mar 6;3(2). pii: e00029-12. doi: 10.1128/mBio.00029-12. Print 2012.

Al Ghouleh I, Magder SNADPH Oxidase-Derived Superoxide Destabilizes LPS-Induced Interleukin-8 mRNA via p38, Erk1/2 MAPK and the Destabilizing Factor Tristetraprolin1. Shock. 2012 Mar 1. [Epub ahead of print]

Oliveinstein R, Al Jahdali H, Alkhamis N, Halwani R, Al-Muhsen S, Hamid QChalleges in the management of severe asthma: role of current and future therapies. Curr Pharm Des. 2011;17(7):703-11. Review.

February 2012

Massoud AH, Ablona A, Mourad W, Piccirillo C, Mazer BAssessment of the immune-modulatory activity of sialylated fraction of IVIg in a murine model of allergic asthma. Allergy Asthma Clin Immunol. 2011 Nov 14;7 Suppl 2:A29. [Epub ahead of print] No abstract available.

Magder SAThe ups and downs of heart rate. Crit Care Med. 2012 Jan;40(1):239-45. Review.

Damjanovic D, Divangahi M, Kugathasan K, Small CL, Zganiacz A, Brown EG, Hogaboam CM, Gauldie J, Xing Z. Negative Regulation of Lung Inflammation and Immunopathology by TNF-α during Acute Influenza Infection. Am J Pathol. 2011 Dec;179(6):2963-76. Epub 2011 Oct 14.

Johnson JR, Hamid Q. Appraising the small airways in asthma. Curr Opin Pulm Med. 2012 Jan;18(1):23-8. Review.

January 2012 

Kimoff RJ, Hamid Q, Divangahi M, Hussain S, Bao W, Naor N, Payne RJ, Ariyarajah A, Mulrain K, Petrof BJIncreased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea. Eur Respir J. 2011 Jul;38(1):89-97. Epub 2010 Sep 16.

Ghezzi CE, Marelli B, Muja N, Hirota N, Martin JG, Barralet JE, Alessandrino A, Freddi G, Nazhat SN.Mesenchymal stem cell-seeded multilayered dense collagen-silk fibroin hybrid for tissue engineering applications. Biotechnol J. 2011 Oct;6(10):1198-207. doi: 10.1002/biot.201100127. Epub 2011 Aug 26.

Martin JG, Novali M. Small animals models for drug discovery. Pulm Pharmacol Ther. 2011 Oct;24(5):513-24. Epub 2011 May 12. Review.

December 2011

Kimoff RJ. To treat or not to treat: can a portable monitor reliably guide decision-making in sleep apnea? Am J Respir Crit Care Med. 2011 Oct 15;184(8):871-2. No abstract available.

de Torres JP, Marín JM, Casanova C, Cote C, Carrizo S, Cordoba-Lanus E, Baz-Dávila R, Zulueta JJ, Aguirre-Jaime A, Saetta M, Cosio MG, Celli BR. Lung cancer in patients with chronic obstructive pulmonary disease– incidence and predicting factors. Am J Respir Crit Care Med. 2011 Oct 15;184(8):913-9.

Robins S, Roussel L, Schachter A, Risse PA, Mogas AK, Olivenstein R, Martin JG, Hamid Q, Rousseau S. Steroid-insensitive ERK1/2-activity Drives CXCL8 Synthesis and Neutrophilia by Airway Smooth Muscle. Am J Respir Cell Mol Biol. 2011 Nov;45(5):984-90. Epub 2011 Apr 14.

Magder SA. The ups and downs of heart rate. Crit Care Med. 2012 Jan;40(1):239-45.

McCusker C, Warrington R. Primary immunodeficiency. Allergy Asthma Clin Immunol. 2011 Nov 10;7 Suppl 1:S11.

Delarosa S, Guillemette J, Papillon J, Han YS, Kristof AS, Cybulsky AV. Activity of the Ste20-like Kinase, SLK, is Enhanced by Homodimerization. Am J Physiol Renal Physiol. 2011 Sep;301(3):F554-64. Epub 2011 Jun 15.

Behar SM, Martin CJ, Nunes-Alves C, Divangahi M, Remold HG. Lipids, apoptosis, and cross-presentation: links in the chain of host defense against Mycobacterium tuberculosis. Microbes Infect. 2011 Aug;13(8-9):749-56. Epub 2011 Mar 31. Review.

November 2011

Wang Y, Li Y, Shan J, Fixman EMcCusker C. Effective treatment of experimental ragweed-induced asthma with STAT-6-IP, a topically delivered cell-penetrating peptide. Clin Exp Allergy. 2011 Nov;41(11):1622-30. doi: 10.1111/j.1365-2222.2011.03853.x. Epub 2011 Sep 20.

Thomas MM, Vigna C, Betik AC, Tupling AR, Hepple RT. Cardiac calcium pump inactivation and nitrosylation in senescent rat myocardium are not attenuated by long-term treadmill training. Exp Gerontol. 2011 Oct;46(10):803-10. Epub 2011 Jul 8.

Al-Muhsen S, Johnson JR, Hamid Q. Remodeling in asthma. J Allergy Clin Immunol. 2011 Sep;128(3):451-62; quiz 463-4. Epub 2011 Jun 2. Review.

Nadigel J, Prefontaine D, Baglole CJ, Bourbeau J, Maltais F, Eidelman DHHamid QCigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8+ T cells in chronic obstructive pulmonary disease. Respir Res. 2011 Nov 9;12(1):149. [Epub ahead of print]

Tang H, Lee M, Budak MT, Pietras N, Hittinger S, Vu M, Khuong A, Hoang CD, Hussain SN, Levine S, Shrager JB. Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis. FASEB J. 2011 Sep;25(9):2921-36. Epub 2011 May 19.

McKim DA, Road J, Avendano M, Abdool S, Cote F, Duguid N, Fraser J, Maltais F, Morrison DL, O’Connell C,  Petrof BJ, Rimmer K, Skomro R. Home mechanical ventilation: A Canadian Thoracic Society clinical practice guideline. Can Respir J. 2011 Jul;18(4):197-215.

Takayama S, Tamaoka M, Takayama K, Okayasu K, Tsuchiya K, Miyazaki Y, Sumi Y, Martin JG, Inase N. Synthetic double-stranded RNA enhances airway inflammation and remodelling in a rat model of asthma. Immunology. 2011 Oct;134(2):140-50. doi: 10.1111/j.1365-2567.2011.03473.x.

October 2011

McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP. Lung-Targeted Overexpression of the NF-κB Member RelB Inhibits Cigarette Smoke-Induced Inflammation. Am J Pathol. 2011 Jul;179(1):125-33. Epub 2011 May 5.

Bergeron C, Tulic MK, Hamid QAirway remodelling in asthma: from benchside to clinical practice. Can Respir J. 2010 Jul-Aug;17(4):e85-93. Review.

Seely AJ, Kauffman SA, Bates JH, Macklem PT, Suki B, Marshall JC, Batchinsky AI, Perez-Velazquez JL, Seiver A, McGregor C, Maksym G, Kamath MV, Similowski T, Buchman TG, Letellier C, Filoche M, Frasch MG, Straus C, Glass L, Godin PJ, Morris JA, Sow D, Nenadovic V, Arnold RC, Norris P, Moorman JR. Proceedings from the Montebello Round Table Discussion. Second annual conference on Complexity and Variability discusses research that brings innovation to the bedside. J Crit Care. 2011 Jun;26(3):325-7. No abstract available.

Muller C, Salehi F, Mazer B, Bouchard M, Adam-Poupart A, Chevalier G, Truchon G, Lambert J, Zayed J. Immunotoxicity of 3 chemical forms of beryllium following inhalation exposure. Int J Toxicol. 2011 Oct;30(5):538-45.

Kimoff RJ. To treat or not to treat: can a portable monitor reliably guide decision-making in sleep apnea? Am J Respir Crit Care Med. 2011 Oct 15;184(8):871-2. No abstract available.

Rowan SL, Purves-Smith FM, Solbak NM, Hepple RTAccumulation of severely atrophic myofibers marks the acceleration of sarcopenia in slow and fast twitch muscles. Exp Gerontol. 2011 Aug;46(8):660-9. Epub 2011 Apr 12.

September 2011

Murias JM, Kowalchuk JM, Ritchie D, Hepple RT, Doherty TJ, Paterson DH.
Adaptations in Capillarization and Citrate Synthase Activity in Response to Endurance Training in Older and Young Men. J Gerontol A Biol Sci Med Sci. 2011 Sep;66(9):957-64. Epub 2011 Jun 29.

Schauberger EM, Ewart SL, Arshad SH, Huebner M, Karmaus W, Holloway JW, Friderici KH, Ziegler JT, Zhang H, Rose-Zerilli MJ, Barton SJ, Holgate ST, Kilpatrick JR, Harley JB, Lajoie-Kadoch S, Harley IT, Hamid Q, Kurukulaaratchy RJ, Seibold MA, Avila PC, Rodriguez-Cintrón W, Rodriguez-Santana JR, Hu D, Gignoux C, Romieu I, London SJ, Burchard EG, Langefeld CD, Wills-Karp M. Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol. 2011 Oct;128(4):753-760.e11. Epub 2011 Jun 22.

Labbe K, Danialou G, Gvozdic D, Demoule A, Divangahi M, Boyd JH, Petrof BJInhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia. Crit Care. 2010;14(5):R187. Epub 2010 Oct 7.

Magder S. Further cautions for the use of ventilatory-induced changes in arterial pressures to predict volume responsiveness. Crit Care. 2010;14(5):197. Epub 2010 Sep 20. Review.

Jaber S, Petrof BJ, Jung B, Chanques G, Berthet JP, Rabuel C, Bouyabrine H, Courouble P, Koechlin C, Sebbane M, Similowski T, Scheuermann V, Mebazaa A, Capdevila X, Mornet D, Mercier J, Lacampagne A, Philips A, Matecki S. Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans. Am J Respir Crit Care Med. 2011 Feb 1;183(3):364-71. Epub 2010 Sep 2.

Magder S. Phenylephrine and tangible bias. Anesth Analg. 2011 Aug;113(2):211-3. No abstract available.

Ribeiro M, Fritscher LG, Al-Musaed AM, Balter MS, Hoffstein V, Mazer BD, Maier LA, Liss GM, Tarlo SM. Search for Chronic Beryllium Disease Among Sarcoidosis Patients in Ontario, Canada. Lung. 2011 Jun;189(3):233-41. Epub 2011 Mar 13.

Kumar PG, Kumar JA, Anumala N, Reddy KP, Avula H, Hussain SN. Volumetric analysis of intrabony defects in aggressive periodontitis patients following use of a novel composite alloplast: a pilot study. Quintessence Int. 2011 May;42(5):375-84.

Picard M, Ritchie D, Thomas MM, Wright KJ, Hepple RT. Alterations in Intrinsic Mitochondrial Function with Aging are Fiber Type-specific and do not Explain Differential Atrophy Between Muscles. Aging Cell. 2011 Sep 20. doi: 10.1111/j.1474-9726.2011.00745.x. [Epub ahead of print]

Grant GE, Gravel S, Guay J, Patel P, Mazer BD, Rokach J, Powell WS. 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes. Free Radic Biol Med. 2011 May 15;50(10):1297-304. Epub 2011 Feb 18.

Leclere M, Lavoie-Lamoureux A, Gélinas-Lymburner E, David F, Martin JG, Lavoie JP. Effect of antigenic exposure on airway smooth muscle remodeling in an equine model of chronic asthma. Am J Respir Cell Mol Biol. 2011 Jul;45(1):181-7. Epub 2010 Oct 8.

Takayama S, Tamaoka M, Takayama K, Okayasu K, Tsuchiya K, Miyazaki Y, Sumi Y, Martin JG, Inase N.Synthetic double-stranded RNA enhances airway inflammation and remodelling in a rat model of asthma. Immunology. 2011 Oct;134(2):140-50. doi: 10.1111/j.1365-2567.2011.03473.x.

Al Heialy S, McGovern TK, Martin JG. Insights into asthmatic airway remodelling through murine models. Respirology. 2011 May;16(4):589-97. doi: 10.1111/j.1440-1843.2011.01974.x. Review.

August 2011

Venkatesan N, Siddiqui S, Jo T, Martin JGLudwig MS. Allergen-induced airway remodeling in Brown Norway rats: structural and metabolic changes in glycosaminoglycans. Am J Respir Cell Mol Biol. 2011 Aug 18. [Epub ahead of print]

Behar SM, Martin CJ, Booty MG, Nishimura T, Zhao X, Gan HX, Divangahi M, Remold HG. Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol. 2011 May;4(3):279-87. Epub 2011 Feb 9. Review.

Chang Y, Nadigel J, Boulais N, Bourbeau J, Maltais F, Eidelman DHHamid Q. CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease. Respir Res. 2011 Apr 10;12:43.

Roussel L, Robins S, Schachter A, Bérubé J, Hamid Q, Rousseau SSteroids and extracellular signal-regulated kinase 1/2 activity suppress activating transcription factor 3 expression in patients with severe asthma. J Allergy Clin Immunol. 2011 Jun;127(6):1632-4. Epub 2011 Apr 22. No abstract available.

Risse PA, Jo T, Suarez F, Hirota N, Tolloczko B, Ferraro P, Grütter P, Martin JG. Interleukin-13 inhibits proliferation and enhances contractility of human airway smooth muscle cells without change in contractile phenotype. Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L958-66. Epub 2011 Apr 1.

Grant GE, Rubino S, Gravel S, Wang X, Patel P, Rokach J, Powell WS. Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid, and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid. Carcinogenesis. 2011 Jun;32(6):822-8. Epub 2011 Mar 10.

Marchica CL, Pinelli V, Borges MC, Zummer J, Narayanan V, Iozzo RV, Ludwig MSA Role for Decorin in a Murine Model of Allergen-Induced Asthma. Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L863-73. Epub 2011 Mar 4.

Bazett M, Paun A, Haston CK. MicroRNA profiling of cystic fibrosis intestinal disease in mice. Mol Genet Metab. 2011 May;103(1):38-43. Epub 2011 Jan 27.

Mofarrahi M, Hussain SNExpression and functional roles of angiopoietin-2 in skeletal muscles.PLoS One. 2011;6(7):e22882. Epub 2011 Jul 29.

July 2011

Torres JP, Marín JM, Casanova C, Cote C, Carrizo S, Cordoba-Lanus E, Baz-Dávila R, Zulueta JJ, Aguirre-Jaime A, Saetta M, Cosio MG, Celli BR. Lung Cancer in patients with COPD: Incidence and predicting factors. Am J Respir Crit Care Med. 2011 Jul 28. [Epub ahead of print]

Picard M, Taivassalo T, Gouspillou G, Hepple RTMitochondria: Isolation, Structure and Function. J Physiol. 2011 Jun 27. [Epub ahead of print]

Magder S. Phenylephrine and tangible bias. Anesth Analg. 2011 Aug;113(2):211-3. No abstract available.

Lehmann GM, Xi X, Kulkarni AA, Olsen KC, Pollock SJ, Baglole CJ, Gupta S, Casey AE, Huxlin KR, Sime PJ, Feldon SE, Phipps RP. The Aryl Hydrocarbon Receptor Ligand ITE Inhibits TGFβ1-Induced Human Myofibroblast Differentiation. Am J Pathol. 2011 Apr;178(4):1556-67. Epub 2011 Mar 3.

Kuna ST, Badr MS, Kimoff RJ, Kushida C, Lee-Chiong T, Levy P, McNicholas WT, Strollo PJ Jr; ATS/AASM/ACCP/ERS Committee on Ambulatory Management of Adults with OSA. An official ATS/AASM/ACCP/ERS workshop report: Research priorities in ambulatory management of adults with obstructive sleep apnea. Proc Am Thorac Soc. 2011 Mar;8(1):1-16.

Roussel L, Martel G, Bérubé J, Rousseau S. P. aeruginosa drives CXCL8 synthesis via redundant toll-like receptors and NADPH oxidase in CFTR∆F508 airway epithelial cells. J Cyst Fibros. 2011 Mar;10(2):107-13. Epub 2010 Dec 21.

Lands LC, Tanswell AK, Laberge S, McCusker C, Ratjen F. Pediatric Respiratory Assembly. Mini symposium on lung inflammation. Can Respir J. 2010 Mar-Apr;17(2):e35-41. No abstract available.

Patel P, Gore V, Powell WS, Rokach J. C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1987-90. Epub 2011 Feb 12.

Patel P, Anumolu JR, Powell WS, Rokach J. 5-Oxo-15-HETE: Total synthesis and bioactivity. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1857-60. Epub 2011 Jan 25.

Mitchell D, Paniker L, Sanchez G, Bella Z, Garaczi E, Szell M, Hamid Q, Kemeny L, Koreck A. Molecular response of nasal mucosa to therapeutic exposure to broad-band ultraviolet radiation. J Cell Mol Med. 2010 Jan;14(1-2):313-22. Epub 2008 Jul 30.

June 2011

Fox J, Gordon JR, Haston CKCombined CXCR1/CXCR2 Antagonism Decreases Radiation-Induced Alveolitis in the Mouse. Radiat Res. 2011 May;175(5):657-64. Epub 2011 Feb 22.

Macklem PT. Stephen Hales, an unrecognized giant of medicine. Osler Libr Newsl. 2010;(114):1-4. No abstract available.

Magder SA. Fluids after cardiac surgery: Do all cardiac surgical patients behave similarly?Crit Care Med. 2011 Jul;39(7):1856. No abstract available.

Halwani R, Al-Abri J, Beland M, Al-Jahdali H, Halayko AJ, Lee TH, Al-Muhsen S, Hamid Q. CC and CXC chemokines induce airway smooth muscle proliferation and survival. J Immunol. 2011 Apr 1;186(7):4156-63. Epub 2011 Mar 2.

McGovern TK, Powell WS, Day BJ, White CW, Govindaraju K, Karmouty-Quintana H, Lavoie N, Tan JJ, Martin JG. Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma. Respir Res. 2010 Oct 6;11:138.

Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid QEidelman DH. T(H)17 cytokines induce human airway smooth muscle cell migration. J J Allergy Clin Immunol. 2011 Apr;127(4):1046-53.e1-2. Epub 2011 Feb 22.

May 2011

Seely AJ, Kauffman SA, Bates JH, Macklem PT, Suki B, Marshall JC, Batchinsky AI, Perez-Velazquez JL, Seiver A, McGregor C, Maksym G, Kamath MV, Similowski T, Buchman TG, Letellier C, Filoche M, Frasch MG, Straus C, Glass L, Godin PJ, Morris JA, Sow D, Nenadovic V, Arnold RC, Norris P, Moorman JR. Proceedings from the Montebello Round Table Discussion. Second annual conference on Complexity and Variability discusses research that brings innovation to the bedside. J Crit Care. 2011 Jun;26(3):325-7. No abstract available.

McCusker C, Hamid Q. Managing asthma during pregnancy: what information do we need to optimize care? Am J Respir Crit Care Med. 2011 Mar 15;183(6):687-8. No abstract available.

Kaminska M, Kimoff RJ, Schwartzman K, Trojan DA. Sleep disorders and fatigue in multiple sclerosis: Evidence for association and interaction. J Neurol Sci. 2011 Mar 15;302(1-2):7-13. Epub 2011 Jan 16. Review.

Doonan RJ, Scheffler P, Lalli M, Kimoff RJ, Petridou ET, Daskalopoulos ME, Daskalopoulou SS. Increased arterial stiffness in obstructive sleep apnea: a systematic review. Hypertens Res. 2011 Jan;34(1):23-32. Epub 2010 Oct 21. Review.

Siddiqui S, Jo T, Tamaoka M, Shalaby KH, Ghezzo H, Bernabeu M, Martin JG. Sites of allergic airway smooth muscle remodeling and hyperresponsiveness are not associated in the rat. J Appl Physiol. 2010 Oct;109(4):1170-8. Epub 2010 Jul 22.

Magder S. Hemodynamic monitoring in the mechanically ventilated patient. Curr Opin Crit Care. 2011 Feb;17(1):36-42. Review.

Canale-Zambrano JC, Haston CKIGF binding protein-3 treatment alters intestinal cell proliferation but not body weight of adult cystic fibrosis transmembrane conductance regulator deficient mice. Pediatr Res. 2011 Feb;69(2):129-34.

McGovern T, Day BJ, White CW, Powell WSMartin JG. AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury. Free Radic Biol Med. 2011 Mar 1;50(5):602-8. Epub 2010 Dec 13.

April 2011

Jiang BH, Tardif JC, Sauvageau S, Ducharme A, Shi Y, Martin JG, Dupuis J. Beneficial effects of atorvastatin on lung structural remodeling and function in ischemic heart failure. J Card Fail. 2010 Aug;16(8):679-88. Epub 2010 Apr 8.

Kumar PG, Kumar JA, Anumala N, Reddy KP, Avula H, Hussain SN. Volumetric analysis of intrabony defects in aggressive periodontitis patients following use of a novel composite alloplast: a pilot study. Quintessence Int. 2011 May;42(5):375-84.

Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, Ferri LE. LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Cancer Res. 2011 Mar 1;71(5):1989-98.

Chang Y, Nadigel J, Boulais N, Bourbeau J, Maltais F, Eidelman DH, Hamid Q. CD8 positive T cells express IL-17 in patients with Chronic Obstructive Pulmonary Disease. Respir Res. 2011 Apr 10;12(1):43. [Epub ahead of print]

Risse PA, Jo T, Suarez F, Hirota N, Tolloczko B, Ferraro P, Grütter P, Martin JG. Interleukin-13 inhibits proliferation and enhances contractility of human airway smooth muscle cells without change in contractile phenotype. Am J Physiol Lung Cell Mol Physiol. 2011 Apr 1. [Epub ahead of print]

March 2011

Jaber S, Jung B, Matecki S,  Petrof BJ. Clinical review: Ventilator-induced diaphragmatic dysfunction – human studies confirm animal model findings! Crit Care. 2011 Mar 11;15(2):206. [Epub ahead of print]

Al Heialy S, McGovern TK, Martin JGInsights into Asthmatic Airway Remodeling through Murine Models. Respirology. 2011 Mar 25. doi: 10.1111/j.1440-1843.2011.01974.x. [Epub ahead of print]

Olivenstein R, Hamid Q. Asthma in the elderly … Their time is right now. Clin Exp Allergy. 2011 Apr;41(4):457-8. doi: 10.1111/j.1365-2222.2011.03702.x.

Venkatesan N, Ouzzine M, Kolb M, Netter P,  Ludwig MSIncreased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L191-203. Epub 2010 Nov 5.

Halwani R, Al-Muhsen S, Al-Jahdali H, Hamid QRole of TGFß in Airway Remodeling in Asthma.Am J Respir Cell Mol Biol. 2011 Feb;44(2):127-33. Epub 2010 Jun 4. Review.

Dyrda P, Tazzeo T, Doharris L, Nilius B, Roman HN, Lauzon AM, Aziz T, Lukic D, Janssen LJ. Acute Response of Airway Muscle to Extreme Temperature Includes Disruption of Actin-Myosin Interaction. Am J Respir Cell Mol Biol. 2011 Feb;44(2):213-21. Epub 2010 Apr 15.

Magder SFluid status and fluid responsiveness. Curr Opin Crit Care. 2010 Aug;16(4):289-96. Review

Kuna ST, Badr MS, Kimoff RJ, Kushida C, Lee-Chiong T, Levy P, McNicholas WT, Strollo PJ Jr; on behalf of the ATS/AASM/ACCP/ERS Committee on Ambulatory Management of Adults with OSA. An Official ATS/AASM/ACCP/ERS Workshop Report: Research Priorities in Ambulatory Management of Adults with Obstructive Sleep Apnea. Proc Am Thorac Soc. 2011 Mar;8(1):1-16.

Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, Ferri LE. LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases {beta}1 Integrin-Mediated Cell Adhesion and Liver Metastasis. Cancer Res. 2011 Mar 1;71(5):1989-98.

February 2011

Tulic MK, Hamid Q. Does airway remodelling occur in the upper airways of patients with allergic rhinitis? Clin Exp Allergy. 2010 Dec;40(12):1714-6. doi: 10.1111/j.1365-2222.2010.03631.x. No abstract available.

Aliverti A, Uva B, Laviola M, Bovio D, Lo Mauro A, Tarperi C, Colombo E, Loomas B, Pedotti A, Similowski T, Macklem PTConcomitant ventilatory and circulatory functions of the diaphragm and abdominal muscles.J Appl Physiol. 2010 Nov;109(5):1432-40. Epub 2010 Sep 2.

Hussain SN, Mofarrahi M, Sigala I, Kim HC, Vassilakopoulos T, Maltais F, Bellenis I, Chaturvedi R, Gottfried SB, Metrakos P, Danialou G, Matecki S, Jaber S, Petrof BJ, Goldberg P. Mechanical Ventilation-induced Diaphragm Disuse in Humans Triggers Autophagy. Am J Respir Crit Care Med. 2010 Dec 1;182(11):1377-86. Epub 2010 Jul 16.

Préfontaine D, Banville-Langelier AA, Fiset PO, Guay J, An J, Mazer M, Hamid QMazer BDChildren with atopic histories exhibit impaired lipopolysaccharide-induced Toll-like receptor-4 signalling in peripheral monocytes. Clin Exp Allergy. 2010 Nov;40(11):1648-57. doi: 10.1111/j.1365-2222.2010.03570.x.]

January 2011

Harfouche R, Echavarria R, Rabbani SA, Arakelian A, Hussein MA, Hussain SN. ESTRADIOL-DEPENDENT REGULATION OF ANGIOPOIETIN EXPRESSION IN BREAST CANCER CELLS. J Steroid Biochem Mol Biol. 2011 Jan;123(1-2):17-24. Epub 2010 Oct 16.

Bullimore SR, Siddiqui S, Donovan GM, Martin JG, Sneyd J, Bates JH, Lauzon AM. Could an increase in airway smooth muscle shortening velocity cause airway hyperresponsiveness? Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L121-31. Epub 2010 Oct 22

Ascah A, Khairhallah M, Daussin F, Bourcier-Lucas C, Godin R, Allen BG, Petrof BJ, Des Rosiers C, Burelle Y. STRESS-INDUCED OPENING OF THE PERMEABILITY TRANSITION PORE IN THE DYSTROPHIN-DEFICIENT HEART IS ATTENUATED BY ACUTE TREATMENT WITH SILDENAFIL.Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H144-53. Epub 2010 Oct 22.

Vazquez-Tello A, Semlali A, Chakir J, Martin JG, Leung DY, Eidelman DHHamid QInduction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines. Clin Exp Allergy. 2010 Sep;40(9):1312-22. Epub 2010 Jun 9.

McGovern T, Risse PA, Tsuchiya K, Hassan M, Frigola G, Martin JGLTD₄ induces HB-EGF-dependent CXCL8 release through EGFR activation in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L808-15. Epub 2010 Oct 1.

Carpe N, Mandeville I, Ribeiro L, Ponton A, Martin JG, Kho AT, Chu JH, Tantisira K, Weiss ST, Raby BA, Kaplan F.Genetic influences on asthma susceptibility in the developing lung. Am J Respir Cell Mol Biol. 2010 Dec;43(6):720-30. Epub 2010 Jan 29.

December 2010

Macklem PT. Susceptibility to Exacerbation in COPD. N Engl J Med. 2010 Dec 30;363(27):2670-1.

Politi AZ, Donovan GM, Tawhai MH, Sanderson MJ, Lauzon AM, Bates JH, Sneyd J. A multiscale, spatially-distributed model of asthmatic airway hyper-responsiveness. J Theor Biol. 2010 Oct 21;266(4):614-24. Epub 2010 Aug 4.

Magder S. Hemodynamic monitoring in the mechanically ventilated patient. Curr Opin Crit Care. 2010 Dec 13. [Epub ahead of print]

November 2010

Richer E, Prendergast C, Zhang DE, Qureshi ST, Vidal SM, Malo D. N-Ethyl-N-Nitrosourea-Induced Mutation in Ubiquitin-Specific Peptidase 18 Causes Hyperactivation of IFN-{alpha}{beta} Signaling and Suppresses STAT4-Induced IFN-{gamma} Production, Resulting in Increased Susceptibility to Salmonella Typhimurium. J Immunol. 2010 Sep 15;185(6):3593-601. Epub 2010 Aug 6.

Toumpanakis D, Kastis GA, Zacharatos P, Sigala I, Michailidou T, Kouvela M, Glynos C, Divangahi M, Roussos C, Theocharis SE, Vassilakopoulos T. Inspiratory Resistive Breathing Induces Acute Lung Injury. Am J Respir Crit Care Med. 2010 Nov 1;182(9):1129-36. Epub 2010 Jul 9.

Kristof AS, You Z, Han YS, Giaid A. Protein expression of urotensin II, urotensin-related peptide and their receptor in the lungs of patients with lymphangioleiomyomatosis. Peptides. 2010 Aug;31(8):1511-6. Epub 2010 Apr 28.

Lafferty EI, Qureshi ST, Schnare M. The role of toll-like receptors in acute and chronic lung inflammation. J Inflamm (Lond). 2010 Nov 25;7(1):57. [Epub ahead of print]

Donovan GM, Bullimore SR, Elvin AJ, Tawhai MH, Bates JH, Lauzon AM, Sneyd J. A Continuous-Binding Cross-Linker Model for Passive Airway Smooth Muscle. Biophys J. 2010 Nov 17;99(10):3164-3171.

Drolet JP, Lefebvre MA, Bernard C, Mitchell D, McCusker C, Mazer BMulticentric castleman disease in a child with primary immunodeficiency. Pediatr Blood Cancer. 2010 Dec 1;55(6):1198-200.

Canale-Zambrano JC, Haston CK. Insulin-like growth factor binding protein-3 treatment alters intestinal cell proliferation but not body weight of adult Cftr deficient mice. Pediatr Res. 2010 Nov 9. [Epub ahead of print]

Tulic MK, Hamid QDoes airway remodelling occur in the upper airways of patients with allergic rhinitis? Clin Exp Allergy. 2010 Dec;40(12):1714-6.

Muller C, Mazer B, Salehi F, Audusseau S, Chevalier G, Truchon G, Larivière P, Paquette V, Lambert J, Zayed J. Urinary levels, tissue concentrations and lung inflammation after nose-only exposure to three different chemical forms of beryllium. J Appl Toxicol. 2010 Jul;30(5):411-5.

Magder S, Potter BJ, Varennes BD, Doucette S, Fergusson DCanadian Critical Care Trials Group. Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids. Crit Care Med. 2010 Nov;38(11):2117-24.

October 2010

Halwani R, Al-Muhsen S, Al-Jahdali H, Hamid Q. Role of TGFß in Airway Remodeling in Asthma. Curr Opin Pharmacol. 2010 Jun;10(3):236-45. Epub 2010 Jun 28. Review.

Shalaby KH, Martin JG. Overview of asthma; the place of the T cell. Curr Opin Pharmacol.Jun;10(3):218-25. Epub 2010 Apr 19. Review.

Karmouty-Quintana H, Tamimi F, McGovern TK, Grover LM, Martin JG, Barralet JE. Sustained steroid release in pulmonary inflammation model. Biomaterials. 2010 Aug;31(23):6050-9

Lavoie-Lamoureux A, Moran K, Beauchamp G, Mauel S, Steinbach F, Lefebvre-Lavoie J, Martin JG, Lavoie JP. IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo. Am J Physiol Lung Cell Mol Physiol. 2010 Oct;299(4):L472-82. Epub 2010 Jul 16.

White CW, Martin JG. Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. JProc Am Thorac Soc. 2010 Jul;7(4):257-63. Review.

Drolet JP, Frangie H, Guay J, Hajoui O, Hamid Q, Mazer BD. B lymphocytes in inflammatory airway diseases. Clin Exp Allergy. 2010 Jun;40(6):841-9. Review.

McGovern TK, Powell WS, Day BJ, White CW, Govindaraju K, Karmouty-Quintana H, Lavoie N, Tan JJ, Martin JGDimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma. Respir Res. 2010 Oct 6;11(1):138. [Epub ahead of print]

September 2010

Champagne KA, Kimoff RJ, Barriga PC, Schwartzman K. Sleep disordered breathing in women of childbearing age & during pregnancy. Indian J Med Res. 2010 Feb;131:285-301. Review.

Shalaby KH, Gold LG, Schuessler TF, Martin JG, Robichaud A. Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness. Respir Res. 2010 Jun 21;11:82.

Drolet JP, Lefebvre MA, Bernard C, Mitchell D, McCusker C, Mazer B. Multicentric castleman disease in a child with primary immunodeficiency. Pediatr Blood Cancer. 2010 Sep 16. [Epub ahead of print]

Ramos-Barbón D, Fraga-Iriso R, Brienza NS, Montero-Martínez C, Verea-Hernando H, Olivenstein R, Lemiere C, Ernst P, Hamid QA, Martin JG. T Cells Localize with Proliferating Smooth Muscle alpha-Actin+ Cell Compartments in Asthma. Am J Respir Crit Care Med. 2010 Aug 1;182(3):317-24

Seely AJ, Macklem PT, Suki B, Goldberger A, Godin P, Batchinsky AI, Longtin A, Jones G, Seiver A, McGregor C, Norris P, Maksym G, Lake D, Costa MD, Marshall JC, Morris JA, Moorman JR, Arnold RC, Perez-Velazquez JL, Nenadovic V.The Wakefield roundtable discussion on complexity and variability at the bedsideJ Crit Care. 2010 Sep;25(3):536-537

August 2010

Bergeron C, Tulic M, Hamid Q. Airway remodelling in asthma: From benchside to clinical practice. Can Respir J. 2010 Jul-Aug;17(4):85-94.

Magder S, Potter BJ, Deverenne B, Doucette S, Fergusson D; for the Canadian Critical Care Trials Group. Fluids after cardiac surgery: A pilot study of the use of colloids versus crystalloids. Crit Care Med. 2010 Aug 26. [Epub ahead of print]

Canale-Zambrano JC, ML, Haston CKToll-like Receptor-4 Genotype Influences the Survival of Cystic Fibrosis Mice.  Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G381-90

Divangahi M, Desjardins D, Nunes-Alves C, Remold HG, Behar SM. Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis. Nat Immunol. 2010 Aug;11(8):751-8

Behar SM, Divangahi M, Remold HG. Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy? Nat Rev Microbiol. 2010 Sep;8(9):668-74

Boilard E, Lai Y, Larabee K, Balestrieri B, Ghomashchi F, Fujioka D, Gobezie R, Coblyn JS, Weinblatt ME, Massarotti EM, Thornhill TS, Divangahi M, Remold H, Lambeau G, Gelb MH, Arm JP, Lee DM. A novel anti-inflammatory role for secretory phospholipase A(2) in immune complex-mediated arthritis. EMBO Mol Med. 2010 May;2(5):172-87.

Bérubé J, Roussel L, Nattagh L, Rousseau S. Loss of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function enhances p38 and ERK MAPKs activation increasing IL-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. J Biol Chem 2010 Jul 16;285(29):22299-307

Halwani R, Al-Muhsen S, Hamid QAirway remodeling in asthma. Curr Opin Pharmacol. 2010; 10 (3) pp. 236-245.

July 2010

Jiang BH, Tardif JC, Sauvageau S, Ducharme A, Shi Y, Martin JG, Dupuis J. Beneficial Effects of Atorvastatin on Lung Structural Remodeling and Function in Ischemic Heart Failure. J Card Fail. 2010 Aug;16(8):679-688. Epub 2010 Apr 8.

Macklem PT
, Seely A. Towards a definition of life. Perspect Biol Med. 2010;53(3):330-40.

Lavoie-Lamoureux A, Moran K, Beauchamp G, Mauel S, Steinbach F, Lefebvre-Lavoie J, Martin JG, Lavoie JP. IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil-chemotactic mediator release ex vivo. Am J Physiol Lung Cell Mol Physiol. 2010 Jul 16. [Epub ahead of print]

Behr MA, Divangahi M, Lalande JD. What’s in a name? The (mis)labelling of Crohn’s as an autoimmune disease. Lancet. 2010 Jul 17;376(9736):202-3. No abstract available.

Préfontaine D, Banville-Langelier AA, Fiset PO, Guay J, An J, Mazer M, Hamid Q, Mazer BD. Children with atopic histories exhibit impaired lipopolysaccharide-induced Toll-like receptor-4 signalling in peripheral monocytes. Clin Exp Allergy. 2010 Jul 16. [Epub ahead of print]

Tsuchiya K, Jo T, Takeda N, Al Heialy S, Siddiqui S, Shalaby KH, Risse PA, Maghni K,  Martin JGEGF receptor activation during allergic sensitization affects IL-6-induced T-cell influx to airways in a rat model of asthma. Eur J Immunol. 2010 Jun;40(6):1590-602.

White CW, Martin JGChlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. Proc Am Thorac Soc. 2010 Jul;7(4):257-63.

Hauber, H.-P., Lavigne, F., Hung, H.-L., Levitt, R.C., Hamid, Q. Effect of Th2 type cytokines on hCLCA1 and mucus expression in cystic fibrosis airways. Journal of Cystic Fibrosis,  9 (4) pp. 277-279 (2010)

McCusker, CImmune modulation in the fetus and newborn: Strategies for asthma prevention. Canadian Respiratory Journal,  17 (2) pp. e39-e40 (2010)

June 2010

Paradis J, Wilke M, Haston CKOsteopenia in Cftr-deltaF508 mice. J Cyst Fibros. 9 (4) pp. 239-245 (2010)

Paun, A., Fox, J., Balloy, V., Chignard, M., Qureshi, S.T., Haston, C.K. Combined Tlr2 and Tlr4 Deficiency Increases Radiation-Induced Pulmonary Fibrosis in MiceInternational Journal of Radiation Oncology Biology Physics,  77 (4) pp. 1198-1205.

Shalaby KH, Gold LG, Schuessler TF, Martin JG, Robichaud A. Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness. Respiratory Research 2010, 11:82 (21 June 2010)

Lavoie KL, Bouthillier D, Bacon SL, Lemière C, Martin J, Hamid Q, Ludwig M, Olivenstein R, Ernst P. Psychologic distress and maladaptive coping styles in patients with severe vs moderate asthma. Chest 137 (6) pp. 1324-1331.

Guo N, Baglole CJ, O’Loughlin CW, Feldon SE, Phipps RP. Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease. J Biol Chem. 2010 May 21;285(21):15794-804.

May 2010

Kim HC, Mofarrahi M, Vassilakopoulos T, Maltais F, Sigala I, Debigare R, Bellenis I, Hussain SN.Expression and functional significance of nicotinamide N-methyl transferase in skeletal muscles of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Apr 15;181(8):797-805.

Manali ED, Lyberopoulos P, Triantafillidou C, Kolilekas LF, Sotiropoulou C, Milic-Emili J, Roussos C, Papiris SA. MRC chronic Dyspnea Scale: Relationships with cardiopulmonary exercise testing and 6-minute walk test in idiopathic pulmonary fibrosis patients: a prospective study. BMC Pulm Med. 2010 May 28;10(1):32. [Epub ahead of print]

Drolet, J.-P., Frangie, H., Guay, J., Hajoui, O., Hamid, Q., Mazer, B.DB lymphocytes in inflammatory airway diseases Clinical and Experimental Allergy,  40 (6) pp. 841-849 (2010).

Thomas DM, Fox J, Haston CKImatinib therapy reduces radiation-induced pulmonary mast cell influx and delays lung disease in the mouse. Int J Radiat Biol. 2010 Jun;86(6):436-44.

Brochard L, Abroug F, Brenner M, Broccard AF, Danner RL, Ferrer M, Laghi F, Magder S, Papazian L, Pelosi P, Polderman KH; ATS/ERS/ESICM/SCCM/SRLF Ad Hoc Committee on Acute Renal Failure. An Official ATS/ERS/ESICM/SCCM/SRLF Statement: Prevention and Management of Acute Renal Failure in the ICU Patient: an international consensus conference in intensive care medicine.Am J Respir Crit Care Med. 2010 May 15;181(10):1128-55.

Hassan M, Jo T, Risse PA, Tolloczko B, Lemière C, Olivenstein R, Hamid Q, Martin JG. Airway smooth muscle remodeling is a dynamic process in severe long-standing asthma. J Allergy Clin Immunol. 2010 May;125(5):1037-1045

Baraldo S, Saetta M, Cosio MGFor whom the “alarm” tolls: how we sense the danger of cigarette smoke and react to it. Am J Respir Crit Care Med. 2010 May 1;181(9):879-80.

April 2010

Al-Samri MT, Benedetti A, Préfontaine D, Olivenstein R, Lemière C, Nair P, Martin JG, Hamid Q. Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples. J Allergy Clin Immunol. 2010 Apr 12 . 125 (5): 1161-1163.

Paun A, Lemay AM, Haston CKGene expression profiling distinguishes radiation-induced fibrosing alveolitis from alveolitis in mice. Radiat Res. 2010 Apr;173(4):512-21.

Champagne KA, Kimoff RJ, Barriga PC, Schwartzman K. Sleep disordered breathing in women of childbearing age & during pregnancy. Indian J Med Res. 2010 Feb;131:285-301.

Kristof ASmTOR signaling in lymphangioleiomyomatosis. Lymphat Res Biol. 2010 Mar;8(1):33-42.

Roussel L, Houle F, Chan C, Yao Y, Bérubé J, Olivenstein R,  Martin JG, Huot J, Hamid Q, Ferri L, Rousseau SIL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. J Immunol. 2010 Apr 15;184(8):4531-7.

Côté MC, Lavoie JR, Houle F, Poirier A, Rousseau S, Huot J. Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1. J Biol Chem. 2010 Mar 12;285(11):8013-21

Camateros P, Marino R, Fortin A, Martin JG, Skamene E, Sladek R, Radzioch D. Identification of novel chromosomal regions associated with airway hyperresponsiveness in recombinant congenic strains of mice. Mamm Genome. 2010 Feb;21(1-2):28-38.

Préfontaine D, Nadigel J, Chouiali F, Audusseau S, Semlali A, Chakir J, Martin JG, Hamid Q. Increased IL-33 expression by epithelial cells in bronchial asthmaJ Allergy Clin Immunol. 2010 Mar;125(3):752-4

Burelle Y, Khairallah M, Ascah A, Allen BG, Deschepper CF, Petrof BJ, Des Rosiers C. Alterations in mitochondrial function as a harbinger of cardiomyopathy: lessons from the dystrophic heart. J Mol Cell Cardiol. 2010 Feb;48(2):310-21. Epub 2009 Sep 18. Review

March 2010

Barreiro E, Hussain SNProtein carbonylation in skeletal muscles: impact on function. Antioxid Redox Signal. 2010 Mar;12(3):417-29. Review.

Petrof BJ, Jaber S, Matecki S. Ventilator-induced diaphragmatic dysfunction. Curr Opin Crit Care2010 Feb;16(1):19-25.

February 2010

Contoli M, Bousquet J, Fabbri LM, Magnussen H, Rabe KF, Siafakas NM, Hamid Q, Kraft M. The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy. 2010 Feb;65(2):141-51

Muller C, Mazer B, Salehi F, Audusseau S, Chevalier G, Truchon G, Larivière P, Paquette V, Lambert J, Zayed J. Urinary levels, tissue concentrations and lung inflammation after nose-only exposure to three different chemical forms of beryllium. J Appl Toxicol. 2010 Feb 23. [Epub ahead of print]

Macklem PTTherapeutic implications of the pathophysiology of COPD. Eur Respir J. 2010 Mar;35(3):676-80

Ryan CM, Floras JS, Logan AG, Kimoff RJ, Series F, Morrison D, Ferguson KA, Belenkie I, Pfeifer M, Fleetham J, Hanly PJ, Smilovitch M, Arzt M, Bradley TD; for the CANPAP Investigators. Shift in sleep apnoea type in heart failure patients in the CANPAP trial. Eur Respir J. 2010 Mar;35(3):592-597

Schmidt M, Demoule A, Cracco C, Gharbi A, Fiamma MN, Straus C, Duguet A, Gottfried SB, Similowski T. Neurally Adjusted Ventilatory Assist Increases Respiratory Variability and Complexity in Acute Respiratory Failure. Anesthesiology. 2010 Mar;112(3):670-681

Barreiro, E., Hussain, S.N.A. Protein carbonylation in skeletal muscles: Impact on function Antioxidants and Redox Signaling,12 (3) pp. 417-429 (2010)

Tulic MK, Christodoulopoulos P, Fiset PO, Vaillancourt P, Lavigne F, Marshall JD, Van Nest G, Eiden JJ, Hamid Q. Local Induction of a Specific Th1 Immune Response by Allergen Linked Immunostimulatory DNA in the Nasal Explants of Ragweed-Allergic Subjects. Allergol Int. 2009 Sep 25;58(4): 565-572.

Macklem PTIn memoriam: Jere Mead (1920-2009). J Appl Physiol. 2009 Dec;107(6):1679. Epub 2009 Oct 8.

Carpe N, Mandeville I, Ribeiro L, Ponton A, Martin JG, Kho AT, Chu JH, Tantisira K, Weiss ST, Raby BA, Kaplan F. Genetic Influences on Asthma Susceptibility in Developing Lung. Am J Respir Cell Mol Biol. 2010 Jan 29.

January 2010

Hyde DM, Hamid Q, Irvin CG. Anatomy, pathology, and physiology of the tracheobronchial tree: emphasis on the distal airways. J Allergy Clin Immunol. 2009 Dec;124(6 Suppl):S72-7.

Muller C, Audusseau S, Salehi F, Truchon G, Chevalier G, Mazer B, Kennedy G, Zayed J. Beryllium contamination and exposure monitoring in an inhalation laboratory setting. Toxicol Ind Health. 2010 Jan 7. [Epub ahead of print]

Hyde DM, Hamid Q, Irvin CG. Anatomy, pathology, and physiology of the tracheobronchial tree: emphasis on the distal airways. J Allergy Clin Immunol. 2009 Dec;124(6 Suppl):S72-7.

Roussel L, Rousseau SIL-17 primes airway epithelial cells lacking functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) to increase NOD1 responses.Biochem Biophys Res Commun. 2010  391 (1) pp. 505-509.

 December 2009

Chang CT, Patel P, Gore V, Song WL, Lawson JA, Powell WS, Fitzgerald GA, Rokach J. A new approach to the synthesis of polyunsaturated deuterated isoprostanes: Total synthesis of d(4)-5-epi-8,12-iso-iPF(3alpha)-VI and d(4)-8,12-iso-iPF(3alpha)-VI. Bioorg Med Chem Lett2009 Dec 1;19(23):6755-8.

Shehata, N., Palda, V., Bowen, T., Haddad, E., Issekutz, T.B., Mazer, B., Schellenberg, R., Warrington, R., Easton, D., Anderson, D., Hume, H.  The Use of Immunoglobulin Therapy for Patients With Primary Immune Deficiency: An Evidence-Based Practice Guideline. Transfusion Medicine Reviews,  24(SUPPL. 1) pp. S28-S50 (2010)

Salito C, Aliverti A, Gierada DS, Deslée G, Pierce RA, Macklem PT, Woods JC. Quantification of trapped gas with CT and 3 He MR imaging in a porcine model of isolated ai rway obstructionRadiology. 2009 Nov;253(2):380-9.

Pinelli V, Marchica CL, Ludwig MSAllergen-induced asthma in C57Bl/6 mice: hyper-responsiveness, inflammation and remodelling. Respir Physiol Neurobiol. 2009 Oct 31;169(1):36-43.

Grant GE, Rokach J, Powell WS5-Oxo-ETE and the OXE receptor. Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):98-104.

November 2009

Ito I, Fixman ED, Asai K, Yoshida M, Gounni AS, Martin JGHamid QPlatelet-derived growth factor and transforming growth factor-beta modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells. Clin Exp Allergy. 2009 Sep;39(9):1370-80.

Takeda N, Maghni K, Daigle S, L’Archevêque J, Castellanos L, Al-Ramli W, Malo JL, Hamid QLong-term pathologic consequences of acute irritant-induced asthma. J Allergy Clin Immunol. 2009 Nov;124(5):975-81.e1.

Labonté I, Hassan M, Risse PA, Tsuchiya K, Laviolette M, Lauzon AM, Martin JGThe effects of repeated allergen challenge on airway smooth muscle structural and molecular remodeling in a rat model of allergic asthma. Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L698-705.

October 2009

Takeda N, Sumi Y, Préfontaine D, Al Abri J, Al Heialy N, Al-Ramli W, Michoud MC, Martin JG, Hamid QEpithelium-derived chemokines induce airway smooth muscle cell migration. Clin Exp Allergy. 2009 Jul;39(7):1018-26

d’Hennezel E, Ben-Shoshan M, Ochs HD, Torgerson TR, Russell LJ, Lejtenyi C, Noya FJ, Jabado N, Mazer B, Piccirillo CA. FOXP3 Forkhead Domain Mutation and Regulatory T Cells in the IPEX Syndrome. N Engl J Med. 2009 Oct 22;361(17):1710-3

Kramer MS, Matush L, Bogdanovich N, Aboud F, Mazer B, Fombonne E, Collet JP, Hodnett E, Mironova E, Igumnov S, Chalmers B, Dahhou M, Platt RW. Health and development outcomes in 6.5-y-old children breastfed exclusively for 3 or 6 mo. Am J Clin Nutr. 2009 Oct;90(4):1070-4.

Préfontaine D, Lajoie-Kadoch S, Foley S, Audusseau S, Olivenstein R, Halayko AJ, Lemière C, Martin JGHamid QIncreased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells. J Immunol. 2009 Oct 15;183(8):5094-103.

Fielhaber JA, Han YS, Tan J, Xing S, Biggs CM, Joung KB, Kristof ASInactivation of mammalian target of rapamycin increases STAT1 nuclear content and transcriptional activity in alpha4- and protein phosphatase 2A-dependent fashion. J Biol Chem. 2009 Sep 4;284(36):24341-53.

September 2009

Marin-Corral J, Minguella J, Ramírez-Sarmiento AL, Hussain SN, Gea J, Barreiro E. Oxidised proteins and superoxide anion production in the diaphragm of severe COPD patients. Eur Respir J. 2009 Jun;33(6):1309-19.

Julien JY, Martin JG, Ernst P, Olivenstein R, Hamid Q, Lemière C, Pepe C, Naor N, Olha A, Kimoff RJPrevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma. J Allergy Clin Immunol. 2009 Aug;124(2):371-6.

August 2009

Bates JH, Bullimore SR, Politi AZ, Sneyd J, Anafi RC, Lauzon AMTransient oscillatory force-length behavior of activated airway smooth muscleAm J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L362-72.

Aliverti A, Bovio D, Fullin I, Dellacà RL, Lo Mauro A, Pedotti A, Macklem PTThe abdominal circulatory pump. PLoS One. 2009;4(5):e5550. Epub 2009 May 14.

Divangahi M, Balghi H, Danialou G, Comtois AS, Demoule A, Ernest S, Haston C, Robert R, Hanrahan JW, Radzioch D, Petrof BJLack of CFTR in Skeletal Muscle Predisposes to Muscle Wasting and Diaphragm Muscle Pump Failure in Cystic Fibrosis Mice. PLoS Genet. 2009 Jul;5(7):e1000586. Epub 2009 Jul 31.

July 2009

Graham FD, Erlemann KR, Gravel S, Rokach J, Powell WSOxidative stress-induced changes in pyridine nucleotides and chemoattractant 5-lipoxygenase products in aging neutrophils. Free Radic Biol Med. 2009 Jul 1;47(1):62-71.

Kramer MS, Matush L, Bogdanovich N, Dahhou M, Platt RW, Mazer BThe low prevalence of allergic disease in Eastern Europe: are risk factors consistent with the hygiene hypothesis? Clin Exp Allergy. 2009 May;39(5):708-16.

Kaminska M, Foley S, Maghni K, Storness-Bliss C, Coxson H, Ghezzo H, Lemière C, Olivenstein R, Ernst P, Hamid Q, Martin JAirway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. J Allergy Clin Immunol. 2009 Jul;124(1):45-51.

Demoule A, Divangahi M, Yahiaoui L, Danialou G, Gvozdic D, Petrof BJChemokine receptor and ligand upregulation in the diaphragm during endotoxemia and Pseudomonas lung infectionMediators Inflamm. 2009;2009:860565. Epub 2009 Apr 29.

Hamid Q, Tulic M. Immunobiology of asthmaAnnu Rev Physiol. 2009;71:489-507.

Magder SReply to BrengelmannJ Appl Physiol. 2009 Jul;107(1):370.

June 2009

Bates JH, Bullimore SR, Politi AZ, Sneyd J, Anafi RC, Lauzon AM. Transient oscillatory force-length behavior of activated airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2009 Jun 12. [Epub ahead of print]

McCusker C, Hotte S, Le Deist F, Hirschfeld AF, Mitchell D, Nguyen VH, Gagnon R, Mazer B, Turvey SE, Jabado N. Relative CD4 lymphopenia and a skewed memory phenotype are the main immunologic abnormalities in a child with Omenn syndrome due to homozygous RAG1-C2633T hypomorphic mutation. Clin Immunol. 2009 Jun;131(3):447-55.

Cosio MG
, Saetta M, Agusti A. Immunologic Aspects of Chronic Obstructive Pulmonary Disease.N Engl J Med. 2009 Jun 4;360(23):2445-2454.

May 2009

Al-Ramli W, Préfontaine D, Chouiali F, Martin JG, Olivenstein R, Lemière C, Hamid Q. TH-17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol. 2009 May;123(5):1185-7.

Fraser VJ, Martin JGMarketing data: Has the rise of impact factor led to the fall of objective language in the scientific article? Respir Res. 2009 May 11;10(1):35.

Aliverti A, Bovio D, Fullin I, Dellacà RL, Lo Mauro A, Pedotti A, Macklem PTThe abdominal circulatory pump. PLoS ONE. 2009;4(5):e5550. Epub 2009 May 14.

Ben Efraim AH, Munitz A, Sherman Y, Mazer BD, Levi-Schaffer F, Eliashar R. Efficient purification of eosinophils from human tissues: a comparative studyJ Immunol Methods. 2009 Apr 15;343(2):91-6.

April 2009

Patel P, Cossette C, Anumolu JR, Erlemann KR, Grant GE, Rokach J, Powell WSSubstrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy-Delta6-long-chain fatty acids. J Pharmacol Exp Ther. 2009 Apr;329(1):335-41.

Chang CT, Patel P, Kang N, Lawson JA, Song WL, Powell WS, FitzGerald GA, Rokach J. Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5523-7.

Kaminsky DA, Lundblad LK, Dixon AE, Olivenstein R, Lang SE, Raymond DM, Bates JH, Hamid Q, Martin JG, Irvin CG. Airway Closure and its Relation to Neutrophilic and Eosinophilic Inflammation in Acute Asthma. Proc Am Thorac Soc. 2009 May;6(3):335.

Bergeron C, Al-Ramli W, Hamid QRemodeling in Asthma. Proc Am Thorac Soc. 2009 May;6(3):301-305.

Bérubé J, Bourdon C, Yao Y, Rousseau SDistinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells. Cell Signal. 2009 Mar;21(3):448-56.

Asai K, Foley SC, Sumi Y, Yamauchi Y, Takeda N, Desrosiers M, Lavigne F, Hamid QAmb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy increases CD4+CD25+ T cells in the nasal mucosa of subjects with allergic rhinitis. Allergol Int. 2008 Dec;57(4):377-81.

Mazer BSpecific oral tolerance induction increased tolerance to milk in children with severe cow’s milk allergy. Evid Based Med. 2009 Apr;14(2):50.

March 2009

Kim HC, Mofarrahi M, Hussain SNSkeletal muscle dysfunction in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2008;3(4):637-58. Review.

Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, Benjamin A, Kimoff RJObstructive sleep apnoea and its association with gestational hypertension. Eur Respir J. 2009 Mar;33(3):559-65.

Samara Z, Raux M, Fiamma MN, Gharbi A, Gottfried SB, Poon CS, Similowski T, Straus C. Effects of inspiratory loading on the chaotic dynamics of ventilatory flow in humans. Respir Physiol Neurobiol. 2009 Jan 1;165(1):82-9.

Salehi F, Zayed J, Audusseau S, Muller C, Truchon G, Plamondon P, L’espérance G, Chevalier G, Mazer B. Immunological responses in C3H/HeJ mice following nose-only inhalation exposure to different sizes of beryllium metal particles. J Appl Toxicol. 2009 Jan;29(1)61-8.

Yang HT, Peggie M, Cohen P, Rousseau SDAZAP1 interacts via its RNA-recognition motifs with the C-termini of other RNA-binding proteinsBiochem Biophys Res Commun. 2009 Mar 13;380(3):705-709

Léguillette R, Laviolette M, Bergeron C, Zitouni N, Kogut P, Solway J, Kachmar L, Hamid QLauzon AMMyosin, transgelin, and myosin light chain kinase: expression and function in asthmaAm J Respir Crit Care Med. 2009 Feb 1;179(3):194-204.

February 2009

Le Bellego F, Perera H, Plante S, Chakir J, Hamid QLudwig MSMechanical strain increases cytokine and chemokine production in bronchial fibroblasts from asthmatic patientsAllergy. 2009 Jan;64(1):32-9.

Tsuchiya K, Isogai S, Tamaoka M, Inase N, Akashi T, Martin JG, Yoshizawa Y. Depletion of CD8+ T cells enhances airway remodelling in a rodent model of asthma. Immunology. 2009 Jan;126(1):45-54.

Moynihan BJ, Tolloczko B, El Bassam S, Ferraro P, Michoud MC, Martin JG, Laberge S. IFN-gamma, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13. Respir Res. 2008 Dec 30;9:84.

Lu Y, Tian C, Danialou G, Gilbert R, Petrof BJ, Karpati G, Nalbantoglu J. Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function. J Biol Chem. 2008 Dec 12;283(50):34720-7.

Magder S, Veerassamy S, Bates JH. A further analysis of why pulmonary venous pressure rises after the onset of LV dysfunction. J Appl Physiol. 2009 Jan;106(1):81-90. 

Magder S
Bench-to-bedside review: Ventilatory abnormalities in sepsisCrit Care. 2009 Jan 15;13(1):202.

Michoud MC, Robert R, Hassan M, Moynihan B, Haston C, Govindaraju V, Ferraro P, Hanrahan JW, Martin JGRole of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle. Am J Respir Cell Mol Biol. 2009 Feb;40(2):217-22

January 2009

Rotstein C, Evans G, Born A, Grossman R, Light RB, Magder S, McTaggart B, Weiss K, Zhanel GG. Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults. Can J Infect Dis Med Microbiol. 2008 Jan;19(1):19-53.

Al-Saab F, Manoukian JJ, Al-Sabah B, Almot S, Nguyen LH, Tewfik TL, Daniel SJ, Schloss MD, Hamid QA. Linking laryngopharyngeal reflux to otitis media with effusion: pepsinogen study of adenoid tissue and middle ear fluid. J Otolaryngol Head Neck Surg. 2008 Aug;37(4):565-71.

December 2008

Abdel-Malak NA, Mofarrahi M, Mayaki D, Khachigian LM, Hussain SN. Early Growth Response-1 Regulates Angiopoietin-1-Induced Endothelial Cell Proliferation, Migration, and Differentiation. Arterioscler Thromb Vasc Biol. 2008 Dec 26; [Epub ahead of print]

Labonté I, Laviolette M, Olivenstein R, Chakir J, Boulet LP, Hamid Q. Quality of bronchial biopsies for morphology study and cell sampling: A comparison of asthmatic and healthy subjects. Can Respir J.2008 Nov-Dec;15(8):431-5.

Choong CK, Macklem PT, Pierce JA, Das N, Lutey BA, Martinez CO, Cooper JD. Airway bypass improves the mechanical properties of explanted emphysematous lungs. Am J Respir Crit Care Med. 2008 Nov 1;178(9):902-5. Epub 2008 Jul 31.

Florian M, Florianova L, Hussain S, Magder S. Interaction of Estrogen and Tumor Necrosis Factor alpha in Endothelial Cell Migration and Early Stage of Angiogenesis. Endothelium. 2008 Sep;15(5):265-275.

McIntyre LA, Fergusson D, Cook DJ, Rankin N, Dhingra V, Granton J, Magder S, Stiell I, Taljaard M, Hebert PC; for the Canadian Critical Care Trials Group. Fluid resuscitation in the management of early septic shock (FINESS): a randomized controlled feasibility trial. Can J Anaesth.2008 Dec;55(12):819-826.

Govindaraju V, Michoud MC, Ferraro P, Arkinson J, Safka K, Valderrama-Carvajal H, Martin JG.The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis. Respir Res. 2008 Dec 1;9(1):76 [Epub ahead of print]

November 2008

Yahiaoui L, Gvozdic D, Danialou G, Mack M, Petrof BJ. CC family chemokines directly regulate myoblast responses to skeletal muscle injury. J Physiol. 2008 Aug 15;586(16):3991-4004. Epub 2008 Jun 19.

Tamaoka M, Hassan M, McGovern T, Ramos-Barbón D, Jo T, Yoshizawa Y, Tolloczko B, Hamid Q, Martin JGThe epidermal growth factor receptor mediates allergic airway remodelling in the rat. Eur Respir J. 2008 Nov;32(5):1213-23.

Patel P, Lee GJ, Kim S, Grant GE, Powell WS, Rokach J. Enantio- and stereospecific syntheses of 15(R)-Me-PGD2, a potent and selective DP2-receptor agonist. J Org Chem. 2008 Sep 19;73(18):7213-8. Epub 2008 Aug 14.

October 2008

Siddiqui S, Martin JG. Structural aspects of airway remodeling in asthma. Curr Allergy Asthma Rep. 2008 Nov;8(6):540-7.

Aliverti A, Macklem PT. Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation. J Appl Physiol. 2008 Aug;105(2):763. No abstract available.

Aliverti A, Macklem PT. The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles.
J Appl Physiol. 2008 Aug;105(2):749-51; discussion 755-7. Epub 2008 Mar 20. No abstract available.

Léguillette R, Zitouni NB, Govindaraju K, Fong LM, Lauzon AM.
Affinity for MgADP and force of unbinding from actin of myosin purified from tonic and phasic smooth muscle. Am J Physiol Cell Physiol. 2008 Sep;295(3):C653-60. Epub 2008 Jul 9.

Jeyanathan M, Mu J, Kugathasan K, Zhang X, Damjanovic D, Small C, Divangahi M, Petrof BJ, Hogaboam CM, Xing Z. Airway delivery of soluble mycobacterial antigens restores protective mucosal immunity by single intramuscular plasmid DNA tuberculosis vaccination: role of proinflammatory signals in the lung. J Immunol.2008 Oct 15;181(8):5618-26.

September 2008

Macklem PT, Irvin CG. Dividing the FEV1 into its component parts. J Appl Physiol. 2008 Jul;105(1):392; author reply 393. No abstract available.

Radiation-induced lung response of AcB/BcA recombinant congenic mice. Lemay AM, Haston CK.Radiat Res. 2008 Sep;170(3):299-306.

Pearson T, Curtis F, Al-Eyadhy A, Al-Tamemi S, Mazer B, Dror Y, Abish S, Bale S, Compton J, Ray R, Scott P, Der Kaloustian VM. An intronic mutation in DKC1 in an infant with Høyeraal-Hreidarsson syndrome. Am J Med Genet A. 2008 Aug 15;146A(16):2159-61. No abstract available.

August 2008

Macklem PT. Emergent phenomena and the secrets of life. J Appl Physiol. 2008 Jun;104(6):1844-6. Epub 2008 Jan 17.

Tuck SA, Ramos-Barbon D, Campbell H, McGovern T, Karmouty-Quintana H, Martin JG.
Time course of airway remodelling after an acute chlorine gas exposure in mice
Respir Res. 2008 Aug 14;9(1):61 [Epub ahead of print]

Moynihan B, Tolloczko B, Michoud MC, Tamaoka M, Ferraro P, Martin JG.
MAP kinases mediate interleukin-13 effects on calcium signaling in human airway smooth muscle cellsAm J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L171-7. Epub 2008 Apr 25.

Mitchell D, Paniker L, Sanchez G, Bella Z, Garaczi E, Szell M, Hamid Q, Kemeny L, Koreck A.
Molecular response of nasal mucosa to therapeutic exposure to broad-band ultraviolet radiation. J Cell Mol Med. 2008 Jul 30; [Epub ahead of print]

July 2008

Guo J, Lin X, Williams MA, Hamid Q, Georas SN. Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses. J Allergy Clin Immunol. 2008 Jul;122(1):195-201, 201.e1-5. Epub 2008 Apr 18.

Rivera RM, Cosio MG, Ghezzo H, Salazar M, Pérez-Padilla R. Comparison of lung morphology in COPD secondary to cigarette and biomass smoke. Int J Tuberc Lung Dis. 2008 Aug;12(8):972-7.

Macklem PT, Irvin CG. Dividing the FEV1 into its component parts. J Appl Physiol. 2008 Jul;105(1):392. No abstract available.

Reynolds PR, Kasteler SD, Cosio MG, Sturrock A, Huecksteadt T, Hoidal JR.
RAGE: developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1094-101. Epub 2008 Apr 4.

Pearson T, Curtis F, Al-Eyadhy A, Al-Tamemi S, Mazer B, Dror Y, Abish S, Bale S, Compton J, Ray R, Scott P, Der Kaloustian VM. An intronic mutation in DKC1 in an infant with Høyeraal-Hreidarsson syndrome. Am J Med Genet A. 2008 Jul 14; [Epub ahead of print]

June 2008

Mofarrahi M, Nouh T, Qureshi S, Guillot L, Mayaki D, Hussain SN. Regulation of angiopoietin expression by bacterial lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L955-63. Epub 2008 Feb 29.

Cossette C, Patel P, Anumolu JR, Sivendran S, Lee GJ, Gravel S, Graham FD, Lesimple A, Mamer OA, Rokach J, Powell WS.
Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant.
J Biol Chem. 2008 Apr 25;283(17):11234-43. Epub 2008 Feb 20.

May 2008

Al Ghouleh I, Magder S. Nicotinamide adenine dinucleotide phosphate (reduced form) oxidase is important for LPS-induced endothelial cell activation. Shock. 2008 May;29(5):553-9.

Macklem PT. Last Word on Viewpoint: Emergent phenomena and the secrets of life. J Appl Physiol. 2008 Jun;104(6):1851.

Khairallah M, Khairallah RJ, Young ME, Allen BG, Gillis MA, Danialou G, Deschepper CF, Petrof BJ, Des Rosiers C Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency. Proc Natl Acad Sci U S A. 2008 May 13;105(19):7028-33. Epub 2008 May 12.

Kinyanjui MW, Fixman ED. Cell-penetrating peptides and proteins: new inhibitors of allergic airways disease. Can J Physiol Pharmacol. 2008 Jan-Feb;86(1-2):1-7. Review.

Rousseau S, Papoutsopoulou M, Symons A, Cook D, Lucocq JM, Prescott AR, O’Garra A, Ley SC, Cohen P. TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. J Cell Sci. 2008 Jan 15;121(Pt 2):149-54.

Patel P, Cossette C, Anumolu JR, Gravel S, Lesimple A, Mamer OA, Rokach J, Powell WS. Structural requirements for activation of the 5-oxo-6E,8Z, 11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. J Pharmacol Exp Ther. 2008 May;325(2):698-707. Epub 2008 Feb 21.

Abdel-Malak NA, Kristof AS, Magder SA, Hussain SN, Srikant CB, Di Battista JA. Angiopoietin-1 promotes endothelial cell proliferation and migration through AP-1-dependent autocrine production of interleukin-8. Blood. 2008 Apr 15;111(8):4145-54. Epub 2008 Feb 5.

Darveau ME, Jacques E, Rouabhia M, Hamid Q, Chakir J. Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa. J Allergy Clin Immunol. 2008 Mar;121(3):692-9. Epub 2008 Jan 14.

Sumi Y, Hamid Q. Airway remodeling in asthma. Allergol Int. 2007 Dec;56(4):341-8.

Cossette I, Monaco P, Aliverti A, Macklem PT. Chest wall dynamics and muscle recruitment during professional flute playing. Respir Physiol Neurobiol. 2008 Feb 1;160(2):187-95. Epub 2007 Sep 21.

Wright JL, Cosio MG, Churg A. Animal models of chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2008 May 2; [Epub ahead of print]

April 2008

Mofarrahi M, Brandes RP, Gorlach A, Hanze J, Terada LS, Quinn MT, Mayaki D, Petrof B, Hussain SN. Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase. Antioxid Redox Signal. 2008 Mar;10(3):559-74.

Florian M, Magder S. Estrogen decreases TNF-alpha and oxidized LDL induced apoptosis in endothelial cells. Steroids. 2008 Jan;73(1):47-58. Epub 2007 Sep 1

Debigaré RMaltais FCôté CHMichaud ACaron MAMofarrahi MLeblanc PHussain SN. Profiling of mRNA Expression in Quadriceps of Patients with COPD and Muscle Wasting. COPD. 2008 Apr;5(2):75-84.

Yang HT, Cohen P, Rousseau S. L-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells. Cell Signal. 2008 Feb;20(2):375-80. Epub 2007 Nov 7.

March 2008

Aliverti A Phd, Macklem PT, Debigare R, Maltais F, O’Donnell DE, Webb KA M Sc. Point: Counterpoint – The major limitations to exercise performance in COPD. J Appl Physiol. 2008 Mar 13; [Epub ahead of print]

February 2008

Kaditis AG, Motoyama EK, Zin W, Maekawa N, Nishio I, Imai T, Milic-Emili J. The effect of lung expansion and positive end-expiratory pressure on respiratory mechanics in anesthetized children. Anesth Analg. 2008 Mar;106(3):775-85.

Persistent osteopenia in adult cystic fibrosis transmembrane conductance regulator-deficient mice. Haston CK, Li W, Li A, Lafleur M, Henderson JE. Am J Respir Crit Care Med. 2008 Feb 1;177(3):309-15.

Govindaraju K, Shan J, Levesque K, Hussain SN, Powell WS, Eidelman DH. Nitration of respiratory epithelial cells by myeloperoxidase depends on extracellular nitrite. Nitric Oxide. 2008 May;18(3):184-94.

Macklem PT. At Last! A Realistic Animal Model of Severe Asthma. Am J Respir Crit Care Med. 2008 Feb 1;177(3):245-6.

D’Antoni ML, Torregiani C, Ferraro P, Michoud MC, Mazer B, Martin JG, Ludwig MS. Effects of decorin and biglycan on human airway smooth muscle cell proliferation and apoptosis. Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L764-71